4-Amino-5-chloro-1-(2-chloroethyl)pyrazole

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 芳基卤化物
• 英文名称: 4-Amino-5-chloro-1-(2-chloroethyl)pyrazole
• 英文别名: 5-Chloro-1-(2-chloroethyl)pyrazol-4-amine
• 化学式: C₅H₇Cl₂N₃
• 分子量: 180.037
• InChiKey: HEMPBUIAPFKDGH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  43.8
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-Amino-5-chloro-1-(2-chloroethyl)pyrazole 、 3-methoxy-4-(5-trifluoromethylpyridine-2-yloxy) phenylacetic acid 、 2-氯-1-甲基吡啶碘化物 在 三乙胺 作用下， 以 四氢呋喃 为溶剂， 以37%的产率得到5-chloro-4-(3-methoxy-4-(5-trifluoromethylpyridine-2-yloxy)phenylacetylamino)-1-(2-chloroethyl) pyrazole
  参考文献：
  名称：

  EP1319657

  摘要：

  公开号：

文献信息

• N-(4-PYRAZOLYL)AMIDE DERIVATIVES, CHEMICALS FOR AGRICULTURAL AND HORTICULTURAL USE, AND USAGE OF THE SAME
  申请人：Nihon Nohyaku Co., Ltd.

  公开号：EP1319657A1

  公开（公告）日：2003-06-18

  N-(4-Pyrazolyl)amide derivatives of the general formula (I), exhibiting excellent control activities as bacteriocides, fungicides, insecticides, or nematicides for agricultural and horticultural use; chemicals for agricultural and horticultural use; and usage of the same, wherein R1 is H, optionally halogenated (C1-C6)alkyl, optionally substituted phenylsulfonyl, optionally substituted phenyl, or the like; R2 and R3 are each H, halogeno, CN, NO2, OH, SH, NH2, optionally halogenated (C1-C6)alkyl, optionally substituted phenyl, or the like; R4 is H, optionally halogenated (C1-C6)alkyl, cyano(C1-C6)alkyl, optionally substituted phenyl(C1-C6)alkyl, or the like; R5 is a group of formula (a) or (b), optionally substituted naphthyl, or the like; and Y is (C1-C6)alkylene, optionally halogenated (C1-C6)alkyl(C1-C6)alkyl(C1-C6)alkylene, or the like.

  通式(I)的 N-(4-吡唑基)酰胺衍生物、 其中 R1 是 H、任选卤代（C1-C6）烷基、任选取代的苯磺酰基、任选取代的苯基或类似物；R2和R3各自是H、卤代、CN、NO2、OH、SH、NH2、任选卤代的(C1-C6)烷基、任选取代的苯基或类似物；R4是H、任选卤代的(C1-C6)烷基、氰基(C1-C6)烷基、任选取代的苯基(C1-C6)烷基或类似物；R5是式(a)或(b)的基团、任选取代的萘基或类似物；Y是(C1-C6)亚烷基、任选卤代的(C1-C6)烷基(C1-C6)烷基或类似物。
• N-(4-pyrazolyl) amide derivatives, chemicals for agricultural and horticultural use, and usage of the same
  申请人：——

  公开号：US20040043904A1

  公开（公告）日：2004-03-04

  N-(4-Pyrazolyl)amide derivatives of the general formula (I), 1 exhibiting excellent control activities as bacteriocides, fungicides, insecticides, or nematicides for agricultural and horticultural use; chemicals for agricultural and horticultural use; and usage of the same, wherein R 1 is H, optionally halogenated (C 1 -C 6 )alkyl, optionally substituted phenylsulfonyl, optionally substituted phenyl, or the like; R 2 and R 3 are each H, halogeno, CN, NO 2 , OH, SH, NH 2 , optionally halogenated (C 1 -C 6 )alkyl, optionally substituted phenyl, or the like; R 4 is H, optionally halogenated (C 1 -C 6 )alkyl, cyano(C 1 -C 6 )alkyl, optionally substituted phenyl(C 1 -C 6 )alkyl, or the like; R 5 is a group of formula (a) or (b), optionally substituted naphthyl, or the like; and Y is (C 1 -C 6 )alkylene, optionally halogenated (C 1 -C 6 )alkyl(C 1 -C 6 )alkyl(C 1 -C 6 )alkylene, or the like.