2-(diphenylhydroxymethyl)pyrrole | 121683-12-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(diphenylhydroxymethyl)pyrrole
• 英文别名: diphenyl-pyrrol-2-yl-methanol；Pyrryl-(2)-diphenyl-carbinol；diphenyl(1H-pyrrol-2-yl)methanol
• CAS: 121683-12-3
• 化学式: C₁₇H₁₅NO
• 分子量: 249.312
• InChiKey: VDJHMOPQXSTIPY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  36
• 氢给体数：
  2
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2-(diphenylhydroxymethyl)pyrrole 在 三氟化硼乙醚 作用下， 以 二氯甲烷 为溶剂， 反应 2.0h， 以20%的产率得到4,4,9,9-tetraphenyl-1H,4H,9H-pyrrolo[2,3-f]indolizine
  参考文献：
  名称：

  4,4,9,9-Tetraphenyl pyrroloindolizine: a structural analogue of calix[2]pyrrole

  摘要：

  本文描述了一种与 calix[2]pyrrole 结构相似的吡咯吲嗪衍生物的合成、光谱和结构特征。在这种衍生物中，两个吡咯环与两个具有 N,α-连接和 α,β-连接的中碳原子相连，从而产生了卡利克吡咯家族中最小的类似物。详细的核磁共振光谱研究和单晶 X 射线分析证实了该分子的指定结构。

  DOI：

  10.1039/c2ob25228g
• 作为产物：
  描述：

  2-吡咯甲酸甲酯 、 苯基溴化镁 以 四氢呋喃 、 甲苯 为溶剂， 反应 2.0h， 以100%的产率得到2-(diphenylhydroxymethyl)pyrrole
  参考文献：
  名称：

  5,5-Diaryldipyrromethanes: syntheses and anion binding properties

  摘要：

  A two-step synthesis of 5,5-diaryldipyrromethanes in good yields is described. The adopted synthetic strategy can be used to tune the substituent at the meso-carbon very easily by choosing the Grignard reagent of interest. Further, the influence of the incorporation of various diaryl units at the mesa-carbon atom in the inherent anion binding affinities of the dipyrromethanes through hydrogen bonding was discussed. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.08.163

文献信息

• Electrophilic heterocycles: Functionalization with enol silyl ethers
  作者：Grant P. Holmin、Jacob C. Hood、Hongfang Xue、Douglas A. Klumpp

  DOI：10.1016/j.tet.2023.133511

  日期：2023.8

  A series of heterocyclic triaryl methanols were prepared and reacted with enol silyl ethers in the presence of ZnCl2. This reaction gave a variety of functionalized heterocyclic products. A mechanism is proposed involving formation triaryl carbocation electrophiles with delocalization of positive charge to positions in the heterocyclic rings. Nucleophilic attack then occurs at a ring position of the

  制备了一系列杂环三芳基甲醇，并在ZnCl 2存在下与烯醇甲硅烷基醚反应。该反应得到多种官能化杂环产物。提出了一种机制，涉及形成三芳基碳阳离子亲电子试剂，并将正电荷离域到杂环中的位置。然后在杂环的环位置发生亲核攻击。
• Process for production of vinyl chloride polymer
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：EP0172427A2

  公开（公告）日：1986-02-26

  This process is a process for production of a vinyl chloride polymer by suspension polymerization or emulsion polymerization of vinyl chloride monomer or a mixture of vinyl chloride monomer with a vinyl monomer copolymerizable with said vinyl chloride monomer in an aqueous medium, characterized in that the polymerization is carried out in a polymerizer, the inner wall surface and portions of the auxiliary equipment thereof which may come into contact with the monomer during polymerization being previously coated with a scaling preventive comprising at least one selected from dyes, pigments and aromatic or heterocyclic compounds having at least 5 conjugated π bonds, while controlling the chloride ion concentration in the reaction mixture to not higher than 100 ppm. According to said process, scaling onto the inner wall surface of a polymerizer, etc. during polymerization can be prevented effectively and surely.

  该工艺是通过氯乙烯单体或氯乙烯单体与可与所述氯乙烯单体共聚的乙烯基单体混合物在水介质中进行悬浮聚合或乳液聚合来生产氯乙烯聚合物的工艺，其特征在于聚合是在聚合器中进行的、内壁表面及其辅助设备中可能在聚合过程中与单体接触的部分事先涂上一层防垢剂，该防垢剂至少包括一种选自染料、颜料和至少有 5 个共轭 π 键的芳香族或杂环化合物的防垢剂，同时控制反应混合物中的氯离子浓度不高于 100 ppm。根据上述工艺，可有效、可靠地防止聚合过程中聚合器等内壁表面结垢。
• Tschelinzew; Tronow; Terentjew, Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1915, vol. 47, p. 1214,1217
  作者：Tschelinzew、Tronow、Terentjew

  DOI：——

  日期：——
• KATRITZKY, ALAN R.;AKUTAGAWAWA, KUNIHIKO, ORG. PREP. AND PROCED. INT., 20,(1988) N, C. 585-590
  作者：KATRITZKY, ALAN R.、AKUTAGAWAWA, KUNIHIKO

  DOI：——

  日期：——
• US4757124A
  申请人：——

  公开号：US4757124A

  公开（公告）日：1988-07-12