Cyclohexylmethylthioketon | 6007-67-6

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫代羰基化合物
• 英文名称: Cyclohexylmethylthioketon
• 英文别名: thioacetylcyclohexane；1-Cyclohexyl-methylthioketon；Cyclohexyl-methylthioketon；(2-Thio-ethyl)-cyclohexan；Thiomethylcyclohexylketon；1-Cyclohexylethanethione
• CAS: 6007-67-6
• 化学式: C₈H₁₄S
• 分子量: 142.265
• InChiKey: FIWWESNFPXEQMT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  9
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  32.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  Cyclohexylmethylthioketon 在 nitrosonium tetrafluoroborate 作用下， 以 二氯甲烷 为溶剂， 反应 0.5h， 以75%的产率得到乙酰基环己烷
  参考文献：
  名称：

  Thiocarbonyl to Carbonyl Group Transformation with Nitrosonium Tetrafluoroborate

  摘要：

  DOI：

  10.1055/s-1984-30974
• 作为产物：
  描述：

  乙酰基环己烷 在 硫化氢 、 正丁胺 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 生成 Cyclohexylmethylthioketon
  参考文献：
  名称：

  Mayer,R. et al., Angewandte Chemie, 1963, vol. 75, p. 1011 - 1014

  摘要：

  DOI：

文献信息

• [EN] N 4-MODIFIED CYTIDINE NUCLEOTIDES AND THEIR USE<br/>[FR] NUCLÉOTIDES DE CYTIDINE MODIFIÉS EN POSITION N 4 ET LEUR UTILISATION
  申请人：UNIV VILNIUS

  公开号：WO2019053609A1

  公开（公告）日：2019-03-21

  The present invention describes W-position modified cytidine nucleotides of formula (I). Provided herein are methods of chemical synthesis of ΛΡ-modified cytidine nucleoside triphosphates and their applications as well as uses of the cytidine analogues for the synthesis of modified nucleic acids. The nucleic acid molecule comprises DNA, RNA or a combination of DNA/RNA. One of many applications of modified cytidine nucleotides described herein is enzyme selection, when an enzyme of interest bears an activity of an esterase, amidase, oxidoreductase, lyase, ligase or other enzymatic activity, formula (I) wherein the substituants are as defined in the appended claims.

  本发明描述了式(I)的W-位置修饰的胞嘧啶核苷酸。本文提供了ΛΡ修饰的胞嘧啶核苷酸三磷酸酯的化学合成方法及其应用，以及胞嘧啶类似物用于合成修饰核酸的用途。核酸分子包括DNA、RNA或DNA/RNA的组合。本文描述的修饰胞嘧啶核苷酸的众多应用之一是酶选择，当感兴趣的酶具有酯酶、酰胺酶、氧化还原酶、裂解酶、连接酶或其他酶活性时，式(I)中的取代基如附图权利要求所定义。
• JANUS KINASE INHIBITORS AND USES THEREOF
  申请人：Purdue Research Foundation

  公开号：US20190127377A1

  公开（公告）日：2019-05-02

  The invention described herein pertains to selective Janus kinase (JAK) inhibitors and methods of use thereof. Also described are methods for treating diseases involved abnormal JAK/STAT signaling pathway in mammals using the described selective JAK inhibitors or a pharmaceutical formulation thereof.

  本发明涉及选择性Janus激酶（JAK）抑制剂及其使用方法。还描述了使用所述选择性JAK抑制剂或其药物配方治疗涉及哺乳动物异常JAK/STAT信号通路的疾病的方法。
• [EN] PROCESS FOR MANUFACTURE OF BLOCKED MERCAPTOSILANE COUPLING AGENTS<br/>[FR] PROCEDE DE FABRICATION D'AGENTS DE LIAISON DE MERCAPTOSILANES BLOQUES
  申请人：GEN ELECTRIC

  公开号：WO2005007660A1

  公开（公告）日：2005-01-27

  Blocked mercaptosilanes can be manufactured by reacting mercaptosilanes with organic or inorganic halides or anhydrides in the presence of an acid acceptor and washing the resulting reaction product with water/brine to yield two immiscible phases: an organic phase containing blocked mercaptosilane product and an aqueous phase containing the salt of the acid acceptor. Recycle of the acid acceptor is achieved by adding base to the aqueous phase. The process is suitable to be run in either batch or continuous mode. The blocked mercaptosilane compounds are used as coupling agents in rubber mixtures.

  阻化巯基硅烷可以通过在酸受体存在下，将巯基硅烷与有机或无机卤化物或酐反应，并用水/盐水洗涤所得的反应产物，得到两个不相溶的相：一个含有阻化巯基硅烷产物的有机相和一个含有酸受体盐的水相。通过向水相中加入碱来回收酸受体。该过程适用于批处理或连续模式运行。阻化巯基硅烷化合物用作橡胶混合物中的偶联剂。
• IMIDATE COMPOUND AND USE THEREOF FOR PEST CONTROL
  申请人：Kamiyama Hideo

  公开号：US20100210683A1

  公开（公告）日：2010-08-19

  There is provided a compound having an excellent controlling effect on arthropod pests represented by the formula (I-1): wherein Z represents an optionally substituted carbocyclic group or an optionally substituted heterocyclic group; G represents a -A 1 -R 1 group, etc.; X 0 represents a -A 2 -R 4 group, etc.; X represents a -A 2 -R 4 group, etc.; X 0 represents a -A 3 -R 6 group, etc.; or X and X 0 are optionally taken together to form a -A 2 -T 0 -A 3 - group; M 1 represents a —R 8 group, etc.; A 1 , A 2 and A 3 independently represent an oxygen atom, etc.; R 1 and R 8 independently represents an optionally substituted C1-C20 chain hydrocarbon group, etc.; R 4 and R 6 independently represent an optionally substituted C1-C6 chain hydrocarbon group, etc.; and T 0 represents an optionally substituted C2-C6 alkanediyl group.

  提供一种化合物，它对于以式(I-1)所代表的节肢动物害虫具有优异的控制效果：其中Z代表可选取代的碳环基团或可选取代的杂环基团；G代表-A1-R1基团等；X0代表-A2-R4基团等；X代表-A2-R4基团等；X0代表-A3-R6基团等；或X和X0可选地结合形成-A2-T0-A3-基团；M1代表-R8基团等；A1、A2和A3独立地代表氧原子等；R1和R8独立地代表可选取代的C1-C20链烃基团等；R4和R6独立地代表可选取代的C1-C6链烃基团等；而T0代表可选取代的C2-C6脂肪二基基团。
• OLAH, G. A.;ARVANAGHI, MASSOUD;OHANNESIAN, L.;SURYA, PRAKASHI, G. K., SYNTHESIS, BRD, 1984, N 9, 785-786
  作者：OLAH, G. A.、ARVANAGHI, MASSOUD、OHANNESIAN, L.、SURYA, PRAKASHI, G. K.

  DOI：——

  日期：——