4-硝基苯基三氟化硫 | 1526-28-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 4-硝基苯基三氟化硫
• 英文名称: 4-Nitro-phenyl-schwefeltrifluorid
• 英文别名: 4-nitrophenylsulphur trifluoride；4-nitrophenylsulfur trifluoride；Trifluoro-(4-nitrophenyl)-lambda4-sulfane；trifluoro-(4-nitrophenyl)-λ4-sulfane
• CAS: 1526-28-9
• 化学式: C₆H₄F₃NO₂S
• 分子量: 211.164
• InChiKey: QEYZGWCLGPZISU-UHFFFAOYSA-N

物化性质

• 熔点：
  56-58 °C
• 密度：
  1.50±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  46.8
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  4-硝基苯基三氟化硫 在 fluorine 作用下， 以44%的产率得到五氟化(4-硝基苯基)硫
  参考文献：
  名称：

  Microreactors for elemental fluorine

  摘要：

  一种微反应器已被设计用于与元素氟结合使用，既用于选择性氟化，也用于有机化合物的全氟化。

  DOI：

  10.1039/a901473j
• 作为产物：
  描述：

  4,4'-二硝基二苯二硫醚 在 potassium fluoride 、 氯 作用下， 以 乙腈 为溶剂， 反应 4.5h， 以98%的产率得到4-硝基苯基三氟化硫
  参考文献：
  名称：

  一种合成有机三氟化硫的新方法

  摘要：

  摘要 阐述了不同类型有机三氟化硫的简单、方便、通用的合成方法，通式为RSF3，其中R=二烷基氨基，芳基或杂环基。该方法包括在过量氟化钾存在下硫代亚硫酸二酰胺、二芳基二硫化物或二杂二硫化物与氯的反应。

  DOI：

  10.1081/scc-120021841

文献信息

• [EN] METHODS FOR PREPARING FLUOROALKYL ARYLSULFINYL COMPOUNDS AND FLUORINATED COMPOUNDS THERETO<br/>[FR] PROCÉDÉS DE PRÉPARATION DE COMPOSÉS FLUOROALKYLE ARYLSULFINYLÉS ET COMPOSÉS FLUORÉS APPARENTÉS
  申请人：IM & T RES INC

  公开号：WO2010022001A1

  公开（公告）日：2010-02-25

  Novel preparative methods for fluoroalkyl arylsulfinyl compounds are disclosed. Fluorinated compounds as useful fluorinated compounds, intermediates, or builing blocks are disclosed. Useful applications of the fluoroalkyl arylsulfinyl compounds are shown.

  揭示了用于制备氟烷基芳基磺酰基化合物的新型制备方法。公开了氟化合物作为有用的氟化合物、中间体或构建块。展示了氟烷基芳基磺酰基化合物的有用应用。
• Process for the synthesis of aryl sulfurpentafluorides
  申请人：AIR PRODUCTS AND CHEMICALS, INC.

  公开号：EP1484318A1

  公开（公告）日：2004-12-08

  A process is described for the synthesis of an aryl sulfur pentafluoride compound. In one embodiment of the present invention, there is provided a process for preparing an aryl sulfurpentafluoride compound comprising: combining an at least one aryl sulfur compound with a fluorinating agent to at least partially react and form an intermediate aryl sulfurtrifluoride product; and exposing the intermediate aryl sulfurtrifluoride product to the fluorinating agent and optionally a fluoride source to at least partially react and form the aryl sulfurpentafluoride compound.

  描述了一种合成芳基硫五氟化合物的过程。在本发明的一个实施例中，提供了一种制备芳基硫五氟化合物的过程，包括：将至少一种芳基硫化合物与氟化剂结合，至少部分反应并形成中间体芳基硫三氟化合物产物；将中间体芳基硫三氟化合物产物暴露于氟化剂和可选的氟化物源，至少部分反应并形成芳基硫五氟化合物。
• Method of performing a chemical reaction
  申请人：British Nuclear Fuels plc

  公开号：US06747178B1

  公开（公告）日：2004-06-08

  According to the present invention there is provided a method of carrying out a chemical reaction between at least two fluids, the method comprising providing respective flow paths for the at least two fluids, said flow paths communicating with each other in a region in which the at least two fluids may contact each other, and flowing the at least two fluids along said flow paths such that in said region the at least two fluids contact each other and a chemical reaction occurs between them, said region having a width perpendicular to the direction of flow in the range 10-10,000 micrometers. It has been found that using a so-called “microreactor”, that is a reactor having dimensions perpendicular to the flow direction of less than 10,000 micrometers, according to the present method, improved control over a fluid chemical reaction can be achieved, which can result in significant improvements in reaction product yield and/or purity, as well as other benefits. The present method has been found to be particularly beneficial for fluorination reactions.

  根据本发明，提供了一种在至少两种流体之间进行化学反应的方法，该方法包括为至少两种流体提供各自的流动路径，这些流动路径在一个区域内相互通信，该区域中至少两种流体可以相互接触，并沿着这些流动路径流动至少两种流体，使得在该区域内至少两种流体相互接触并发生化学反应，该区域的宽度与流动方向垂直在10-10,000微米范围内。已经发现，使用所谓的“微反应器”，即在流动方向上尺寸小于10,000微米的反应器，根据本方法，可以实现对流体化学反应的改进控制，这可以导致反应产物产量和/或纯度显着提高，以及其他好处。已发现，本方法特别有益于氟化反应。
• SUBSTITUTED PHENYLSULFUR TRIFLUORIDE AND OTHER LIKE FLUORINATING AGENTS
  申请人：UMEMOTO TERUO

  公开号：US20080039660A1

  公开（公告）日：2008-02-14

  Novel substituted phenylsulfur trifluorides that act as fluorinating agents are disclosed. Also disclosed are methods for their preparation and methods for their use in introducing one or more fluorine atoms into target substrate compounds. Finally, various intermediate compounds for use in preparing substituted phenylsulfur trifluorides are provided.

  本发明揭示了一种替代苯基硫三氟化物，可作为氟化试剂。还揭示了其制备方法和在引入一个或多个氟原子到目标底物化合物中使用的方法。最后，提供了用于制备替代苯基硫三氟化物的各种中间化合物。
• Methods For Preparing Fluoroalkyl Arylsulfinyl Compounds And Fluorinated Compounds Thereto
  申请人：Umemoto Teruo

  公开号：US20110190511A1

  公开（公告）日：2011-08-04

  Novel preparative methods for fluoroalkyl arylsulfinyl compounds are disclosed. Fluorinated compounds as useful fluorinated compounds, intermediates, or builing blocks are disclosed. Useful applications of the fluoroalkyl arylsulfinyl compounds are shown.

  本发明揭示了一种用于制备氟烷基芳基亚磺酰化合物的新型制备方法。本发明还揭示了氟化合物作为有用的氟化合物、中间体或构建块。同时，本发明还展示了氟烷基芳基亚磺酰化合物的有用应用。