4-Undec-10-enoxy-4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione | 870482-09-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: 4-Undec-10-enoxy-4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione
• 英文别名: 4-undec-10-enoxy-4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione
• CAS: 870482-09-0
• 化学式: C₂₀H₂₉NO₃
• 分子量: 331.455
• InChiKey: LWJHGFVECMVYDI-UHFFFAOYSA-N

物化性质

• 沸点：
  426.8±55.0 °C(Predicted)
• 密度：
  1.10±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  24
• 可旋转键数：
  11
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  46.6
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  4-Undec-10-enoxy-4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione 在 肼 作用下， 以 乙醇 为溶剂， 以96%的产率得到O-Undec-10-enyl-hydroxylamine
  参考文献：
  名称：

  Hydroxylamine-functionalised silica surfaces for biochip applications

  摘要：

  The syntheses of triethoxy and trimethoxy silanes possessing an unprotected hydroxylamine group are described. The grafting of these coupling agents at the surface of oxidised silicon wafers was studied. Accessibility of the hydroxylamine group at the surface was demonstrated with chemical reagents, and the surface proved efficient for covalent immobilisation of peptides possessing the COCHO function. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2005.09.084
• 作为产物：
  描述：

  11-溴-1-十一烯 、 N-羟基-5-降冰片烯-2,3-二甲酰亚胺 在 potassium carbonate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 以90%的产率得到4-Undec-10-enoxy-4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione
  参考文献：
  名称：

  Hydroxylamine-functionalised silica surfaces for biochip applications

  摘要：

  The syntheses of triethoxy and trimethoxy silanes possessing an unprotected hydroxylamine group are described. The grafting of these coupling agents at the surface of oxidised silicon wafers was studied. Accessibility of the hydroxylamine group at the surface was demonstrated with chemical reagents, and the surface proved efficient for covalent immobilisation of peptides possessing the COCHO function. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2005.09.084