5-氨基-2-氯-4-氟苯硫醇 | 99719-10-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯硫酚类
• 中文名称: 5-氨基-2-氯-4-氟苯硫醇
• 英文名称: 2-chloro-4-fluoro-5-aminophenylthiol
• 英文别名: 4-chloro-2-fluoro-5-mercaptoaniline；5-amino-2-chloro-4-fluoro-thiophenol；5-amino-2-chloro-4-fluorothiophenol；Benzenethiol, 5-amino-2-chloro-4-fluoro-；5-amino-2-chloro-4-fluorobenzenethiol
• CAS: 99719-10-5
• 化学式: C₆H₅ClFNS
• 分子量: 177.63
• InChiKey: RZBYHILVAYXNPG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  27
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  5-氨基-2-氯-4-氟苯硫醇 生成 2-N-[4-chloro-5-[[ethoxy(ethyl)phosphoryl]methylsulfanyl]-2-fluorophenyl]-1-N-hexylcyclohexene-1,2-dicarboxamide
  参考文献：
  名称：

  摘要：

  DOI：
• 作为产物：
  描述：

  2-Chloro-4-fluoro-5-nitrobenzenesulfonyl chloride 生成 5-氨基-2-氯-4-氟苯硫醇
  参考文献：
  名称：

  KODZIMO, SIGEHRU;XATANO, MASAMI;TANINAKA, CATOPY

  摘要：

  DOI：

文献信息

• Condensed heterocyclic derivatives and herbicides
  申请人：Nissan Chemical Industries, Ltd.

  公开号：US05039331A1

  公开（公告）日：1991-08-13

  A condensed heterocyclic derivative having the formula: ##STR1## wherein X is an oxygen atom or a sulfur atom; and Z is ##STR2##

  一种具有以下化学式的缩合杂环衍生物：其中X是氧原子或硫原子；Z是
• 2-substituted phenyl-3-chlorotetrahydro-2H-indazoles composition
  申请人：Sumitomo Chemical Co., Ltd.

  公开号：US04752325A1

  公开（公告）日：1988-06-21

  A compound of the formula: ##STR1## wherein R is a C.sub.2 -C.sub.3 alkyl group, a C.sub.3 -C.sub.4 alkenyl group or a C.sub.3 -C.sub.4 alkynyl group and X is a chlorine atom or a bromine atom, which is useful as a herbicide.

  一种化合物的分子式为：##STR1## 其中R是一个C.sub.2-C.sub.3烷基、一个C.sub.3-C.sub.4烯基或一个C.sub.3-C.sub.4炔基，X是一个氯原子或溴原子，可用作除草剂。
• Herbicidally active thiadiazabicyclononanes and nonenes
  申请人：Ciba-Geigy Corporation

  公开号：US05180418A1

  公开（公告）日：1993-01-19

  Cycloalkanecarboxylic acid derivatives of formula I ##STR1## wherein W is ##STR2## and A is CO--R.sub.3 or CN; R.sub.1 is hydrogen or fluorine; R.sub.2 is halogen or cyano; R.sub.3 is chlorine, X--R.sub.5, amino, C.sub.1 -C.sub.4 alkylamino, d-C.sub.1 -C.sub.4 alkylamino, C.sub.2 -C.sub.4 haloalkylamino, di-C.sub.2 -C.sub.4 haloalkylamino, C.sub.1 -C.sub.4 hydroxyalkylamino, di-C.sub.1 -C.sub.4 hydroxyalkylamino, C.sub.3 -C.sub.4 alkenylamino, diallylamino, --N-pyrrolidino, --N-piperidino, --N-morpholino, --N-thiomorpholino, --N-piperidazino, the group --O--N.dbd.C--(R.sub.9)R.sub.10 or the group --N--R.sub.6 (OR.sub.6); each of R.sub.4 and R.sub.14, independently of the other, is hydrogen, fluorine, chlorine, bromine, C.sub.1 -C.sub.4 alkyl or trifluoromethyl; R.sub.5 is hydrogen, C.sub.1 -C.sub.10 alkyl, C.sub.1 -C.sub.4 alkoxy-C.sub.1 -C.sub.4 alkyl, halo-C.sub.1 -C.sub.8 alkyl, C.sub.1 -C.sub.10 alkylthio-C.sub.1 -C.sub.4 alkyl, di-C.sub.1 -C.sub.4 alkylamino-C.sub.1 -C.sub.4 alkyl, cyano-C.sub.1 -C.sub.8 alkyl, C.sub.3 -C.sub.8 alkenyl, halo-C.sub.3 -C.sub. 8 alkenyl, C.sub.3 -C.sub.8 alkynyl, C.sub.3 -C.sub.7 cycloalkyl, C.sub.3 -C.sub.7 cycloalkyl-C.sub.1 -C.sub.4 alkyl or halo-C.sub.3 -C.sub.7 cycloalkyl, or benzyl which is unsubstituted or substituted at the phenyl ring by up to three identical or different substituents selected from halogen, C.sub.1 -C.sub.4 alkyl, halo-C.sub.1 -C.sub.4 alkyl, halo-C.sub.1 -C.sub.4 alkoxy or C.sub.1 -C.sub.4 alkoxy, or is an alkali metal ion, an alkaline earth metal ion or an ammonium ion, the group --[CHR.sub.6 --(CH.sub.2).sub.m ]--COOR.sub.7, or the group [CHR.sub.6 --(CH.sub.2).sub.t --Si(R.sub.8).sub.3 ]; R.sub.6 is hydrogen or C.sub.1 -C.sub.4 alkyl; R.sub.7 is hydrogen, C.sub.1 -C.sub.6 alkyl, C.sub.3 -C.sub.8 alkenyl, C.sub.3 -C.sub.8 alkynyl, C.sub.1 -C.sub.8 alkoxy-C.sub.2 -C.sub.8 alkyl, C.sub.1 -C.sub.8 alkylthio-C.sub.2 -C.sub.8 alkyl or C.sub.3 -C.sub.7 cycloalkyl; R.sub.8 is C.sub.1 - C.sub.4 alkyl; R.sub.9 is C.sub.1 -C.sub.4 alkyl; R.sub.10 is C.sub.1 -C.sub.4 alkyl or phenyl; or R.sub.9 and R.sub.10, together with the carbon atom to which they are bonded, form a cyclohexane ring; R.sub.11 is C.sub.1 -C.sub.8 alkyl; R.sub.12 is hydrogen or C.sub.1 -C.sub.8 alkyl; R.sub.13 is hydrogen, C.sub.1 -C.sub.6 alkyl, C.sub.3 -C.sub.7 cycloalkyl, C.sub.1 -C.sub.4 alkoxy-C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkylthio-C.sub.1 -C.sub.4 alkyl, halo-C.sub.1 -C.sub.7 alkyl, C.sub.3 -C.sub.7 alkenyl or C.sub.3 -C.sub.7 alkynyl; X, Y, Y.sub.1, Y.sub.2, Y.sub.3, Y.sub.4, Z.sub.1 and Z.sub.2 are each independently oxygen or sulfur; n is 0, 1, 2, 3 or 4; m is 0, 1, 2, 3 or 4; q is 1 or 2; and t is 0, 1, 2, 3 or 4, have good pre- and post-emergence selective herbicidal and growth regulating properties.

  公式I的环烷基羧酸衍生物 其中W为##STR2##，A为CO--R.sub.3或CN；R.sub.1为氢或氟；R.sub.2为卤素或氰基；R.sub.3为氯、X--R.sub.5、氨基、C.sub.1-C.sub.4烷基氨基、d-C.sub.1-C.sub.4烷基氨基、C.sub.2-C.sub.4卤代烷基氨基、di-C.sub.2-C.sub.4卤代烷基氨基、C.sub.1-C.sub.4羟基烷基氨基、di-C.sub.1-C.sub.4羟基烷基氨基、C.sub.3-C.sub.4烯基氨基、二烯丙基氨基、--N-吡咯啉基、--N-哌啶基、--N-吗啉基、--N-硫代吗啉基、--N-哌嗪基、基团--O--N.dbd.C--(R.sub.9)R.sub.10或基团--N--R.sub.6(OR.sub.6)；R.sub.4和R.sub.14分别独立地为氢、氟、氯、溴、C.sub.1-C.sub.4烷基或三氟甲基；R.sub.5为氢、C.sub.1-C.sub.10烷基、C.sub.1-C.sub.4烷氧基-C.sub.1-C.sub.4烷基、卤代-C.sub.1-C.sub.8烷基、C.sub.1-C.sub.10烷硫基-C.sub.1-C.sub.4烷基、二-C.sub.1-C.sub.4烷基氨基-C.sub.1-C.sub.4烷基、氰基-C.sub.1-C.sub.8烷基、C.sub.3-C.sub.8烯基、卤代-C.sub.3-C.sub.8烯基、C.sub.3-C.sub.8炔基、C.sub.3-C.sub.7环烷基、C.sub.3-C.sub.7环烷基-C.sub.1-C.sub.4烷基或卤代-C.sub.3-C.sub.7环烷基、或苄基，该苄基在苯环上未被取代或被选自卤素、C.sub.1-C.sub.4烷基、卤代-C.sub.1-C.sub.4烷基、卤代-C.sub.1-C.sub.4烷氧基或C.sub.1-C.sub.4烷氧基的最多三个相同或不同的取代基取代，或是碱金属离子、碱土金属离子或铵离子，该基团--[CHR.sub.6 --(CH.sub.2).sub.m ]--COOR.sub.7或基团[CHR.sub.6 --(CH.sub.2).sub.t --Si(R.sub.8).sub.3]；R.sub.6为氢或C.sub.1-C.sub.4烷基；R.sub.7为氢、C.sub.1-C.sub.6烷基、C.sub.3-C.sub.8烯基、C.sub.3-C.sub.8炔基、C.sub.1-C.sub.8烷氧基-C.sub.2-C.sub.8烷基、C.sub.1-C.sub.8烷硫基-C.sub.2-C.sub.8烷基或C.sub.3-C.sub.7环烷基；R.sub.8为C.sub.1-C.sub.4烷基；R.sub.9为C.sub.1-C.sub.4烷基；R.sub.10为C.sub.1-C.sub.4烷基或苯基；或R.sub.9和R.sub.10与它们连接的碳原子一起形成一个环己烷环；R.sub.11为C.sub.1-C.sub.8烷基；R.sub.12为氢或C.sub.1-C.sub.8烷基；R.sub.13为氢、C.sub.1-C.sub.6烷基、C.sub.3-C.sub.7环烷基、C.sub.1-C.sub.4烷氧基-C.sub.1-C.sub.4烷基、C.sub.1-C.sub.4烷硫基-C.sub.1-C.sub.4烷基、卤代-C.sub.1-C.sub.7烷基、C.sub.3-C.sub.7烯基或C.sub.3-C.sub.7炔基；X、Y、Y.sub.1、Y.sub.2、Y.sub.3、Y.sub.4、Z.sub.1和Z.sub.2各自独立地为氧或硫；n为0、1、2、3或4；m为0、1、2、3或4；q为1或2；t为0、1、2、3或4。该衍生物具有良好的前后除草和生长调节性能。
• Disulfide compound
  申请人：Ihara Chemical Industry Co., Ltd.

  公开号：US05248822A1

  公开（公告）日：1993-09-28

  A novel disulfide compound is presented which can be readily led to 5-amino-2-chloro-4-fluoro-thiophenol in good yield. A bis-(5-acetamino-2-chloro-4-fluorobenzene)disulfide compound represented by the formula (1): ##STR1##

  介绍了一种新的二硫化合物，可以轻松地得到良好的产量5-氨基-2-氯-4-氟-噻唑酚。该化合物由式（1）表示，其中包括双（5-乙酰氨基-2-氯-4-氟苯）二硫化合物：##STR1##
• Uracil derivatives, and their production and use
  申请人：Sumitomo Chemical Company, Limited

  公开号：US05169431A1

  公开（公告）日：1992-12-08

  A compound of the formula: ##STR1## wherein R is a lower alkyl group, A is a hydrogen atom, a fluorine atom or a chlorine atom, X is an oxygen atom or a sulfur atom, Y is a hydrogen atom, a fluorine atom, a chlorine atom or a bromine atom and Z is a methyl group or an amino group, which is useful as a herbicide.

  一种化合物的公式：##STR1## 其中R是低碳基团，A是氢原子，氟原子或氯原子，X是氧原子或硫原子，Y是氢原子，氟原子，氯原子或溴原子，Z是甲基基团或氨基基团，该化合物可用作除草剂。