potassium trifluoro(3-isopropylphenyl)borate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: potassium trifluoro(3-isopropylphenyl)borate
• 英文别名: potassium;trifluoro-(3-propan-2-ylphenyl)boranuide
• 化学式: C₉H₁₁BF₃*K
• 分子量: 226.091
• InChiKey: FUBAIFGLJYIPHO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.13
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  potassium trifluoro(3-isopropylphenyl)borate 在 lithium hydroxide monohydrate 、 silver trifluoromethanesulfonate 、 Selectfluor 作用下， 以 乙酸乙酯 为溶剂， 以68%的产率得到m-Fluorcumol
  参考文献：
  名称：

  Silver-mediated fluorination of potassium aryltrifluoroborates with Selectfluor®

  摘要：

  A simple and practical procedure for the silver-mediated fluorination of aryl- and heteroaryltrifluoroborates with electrophilic fluorine from Selectfluor (R) and LiOH center dot H2O is presented. The reaction procedure is simple and easy to set up, the process produces fluorinated arenes and heteroarenes in good to excellent yields and a wide range of electronically and structurally diverse substrates are tolerated. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2014.10.055

文献信息

• Synthesis of Aryl Fluorides from Potassium Aryltrifluoroborates and Selectfluor® Mediated by Iron(III) Chloride
  作者：Srinivas Dubbaka、Satyanarayana Gadde、Venkateswara Narreddula

  DOI：10.1055/s-0034-1379942

  日期：——

  synthesis of fluorinated arenes by the iron-mediated fluo­rination of potassium aryltrifluoroborates with Selectfluor® and potassium fluoride is described. The fluorination reaction uses commercially available reagents and without requiring the addition of exogenous ligands. Fluorinated compounds were obtained in moderate to good yields under mild reaction conditions. The synthesis of fluorinated arenes

  献给保罗Knochel教授在他的59之际个生日 抽象 由钾aryltrifluoroborates用的Selectfluor的铁介导的氟化氟化芳烃的合成®和氟化钾进行说明。氟化反应使用可商购的试剂，而无需添加外源配体。在温和的反应条件下，以中等至良好的产率获得了氟化化合物。 由钾aryltrifluoroborates用的Selectfluor的铁介导的氟化氟化芳烃的合成®和氟化钾进行说明。氟化反应使用可商购的试剂，而无需添加外源配体。在温和的反应条件下，以中等至良好的产率获得了氟化化合物。
• Copper-Mediated Oxidative Trifluoromethylthiolation of Potassium Aryltrifluoroborates with Elemental Sulfur and Ruppert–Prakash Reagent
  作者：Srinivas Dubbaka、Azmi Atthunuri、Koraboina Prakash、Prabhu Rangabashyam、Satyanarayana Gadde、Rajesh Kothandaraman

  DOI：10.1055/s-0035-1561565

  日期：——

  procedure for the copper-mediated oxidative trifluoromethylthiolation of potassium aryl- and heteroaryltrifluoroborates with Ruppert–Prakash reagent and elemental sulfur is presented. Aryl trifluoromethyl thioethers can be prepared in good to moderate yield under mild reaction conditions. A facile procedure for the copper-mediated oxidative trifluoromethylthiolation of potassium aryl- and heteroaryltrifluoroborates

  §这些作者同等贡献这项工作。 抽象的 提出了使用Ruppert-Prakash试剂和元素硫对铜介导的芳基和杂芳基三氟硼酸钾的氧化三氟甲基硫醇化的简便方法。芳基三氟甲基硫醚可以在温和的反应条件下以良好至中等的产率制备。 提出了使用Ruppert-Prakash试剂和元素硫对铜介导的芳基和杂芳基三氟硼酸钾的氧化三氟甲基硫醇化的简便方法。芳基三氟甲基硫醚可以在温和的反应条件下以良好至中等的产率制备。
• Silver-mediated fluorination of potassium aryltrifluoroborates with Selectfluor®
  作者：Srinivas Reddy Dubbaka、Venkateswara Reddy Narreddula、Satyanarayana Gadde、Thresen Mathew

  DOI：10.1016/j.tet.2014.10.055

  日期：2014.12

  A simple and practical procedure for the silver-mediated fluorination of aryl- and heteroaryltrifluoroborates with electrophilic fluorine from Selectfluor (R) and LiOH center dot H2O is presented. The reaction procedure is simple and easy to set up, the process produces fluorinated arenes and heteroarenes in good to excellent yields and a wide range of electronically and structurally diverse substrates are tolerated. (C) 2014 Elsevier Ltd. All rights reserved.