N,N-di-p-tolyl urea

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N,N-di-p-tolyl urea
• 英文别名: bis-(4-methylphenyl)-urea；N,N-Di-p-tolyl-harnstoff；N'-Di-p-tolyl-harnstoff；1,1-bis(4-methylphenyl)urea
• 化学式: C₁₅H₁₆N₂O
• 分子量: 240.305
• InChiKey: ISGAHYGIDDEIGR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  46.3
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  N,N-di-p-tolyl urea 生成 N,N',N''-tris(4-methylphenyl)guanidine
  参考文献：
  名称：

  Barr, Chemische Berichte, 1886, vol. 19, p. 1765

  摘要：

  DOI：
• 作为产物：
  描述：

  di-p-tolylcarbamic chloride 在 甲醇 、 氨 作用下， 生成 N,N-di-p-tolyl urea
  参考文献：
  名称：

  Stolle, Journal fur praktische Chemie (Leipzig 1954), 1927, vol. <2> 117, p. 206

  摘要：

  DOI：

文献信息

• Putin's Russia: slowing the pendulum without stopping the clock
  作者：Martin Nicholson

  DOI：10.1111/1468-2346.00223

  日期：2001.10

  Vladimir Putin has been president of Russia for eighteen months, sufficienttime for some judgement about his style of leadership and achievements to have been made. He set out to restore order to a Russia that was fragmenting in Yeltsin's latter years and to revive Russians' pride in their country. Nonetheless, he remains committed to a liberal market economy integrated with the world economy. He encouraged force to bring order to Chechnya, but has not really tackled the problem of reconstruction. He has brought the regions under greater control by the centre, but has been prepared to compromise to avoid confrontation. His most tangible achievement to date has been in championing legislation, most of it long overdue, to establish the legal basis of a market economy. He has been able to exploit a working majority in the parliament, which Yeltsin never enjoyed. The success of this enterprise will depend to some degree on its political context. Persistent efforts by Putin and his team to exert control over the political process and the media will be counterproductive if they concentrate power with the president but leave him without broadly based, independent political support. Putin is likely to remain in power until 2008, however, so he has time on his side.

  弗拉基米尔-普京担任俄罗斯总统已有 18 个月，这段时间足以让人们对他的领导风格和成就做出一些判断。在叶利钦晚年，俄罗斯四分五裂，普京致力于恢复秩序，重振俄罗斯人对国家的自豪感。尽管如此，他仍然致力于与世界经济接轨的自由市场经济。他鼓励用武力为车臣带来秩序，但并未真正解决重建问题。他加强了中央对各地区的控制，但为了避免对抗，他准备做出妥协。迄今为止，他最显著的成就是倡导立法，为市场经济奠定法律基础，其中大部分立法早该出台。他利用了叶利钦从未享有过的议会工作多数。这项事业的成功在一定程度上取决于其政治背景。如果普京及其团队坚持不懈地控制政治进程和媒体，将权力集中在总统手中，却让他失去基础广泛的独立政治支持，那么结果将适得其反。不过，普京很可能会执政到 2008 年，因此他还有时间。
• SYNTHESIS AND INFRARED SPECTRA OF GUANYLUREAS
  作者：Paul A. Boivin、W. Bridgeo、Jean L. Boivin

  DOI：10.1139/v54-032

  日期：1954.3.1

  When 1-amidino-3-nitrourea is reacted in aqueous solutions of amines, nitrous oxide and carbon dioxide are eliminated and guanylureas are formed, together with disubstituted ureas as by-products. The infrared absorption spectra of some disubstituted ureas and nitrates of guanylureas are discussed with tentative assignment of bands to some groups.

  当1-氨基甲酰基-3-硝基脲在胺的水溶液中反应时，会消除一氧化二氮和二氧化碳，并形成鸟氨酰脲，同时产生双取代脲作为副产物。讨论了一些双取代脲和鸟氨酰脲硝酸盐的红外吸收光谱，并对一些基团的带进行了初步分配。
• N-Substituted Carbamic Acid Ester Production Method, Isocyanate Production Method Using Such N-Substituted Carbamic Acid Ester, And Composition For Transfer And Storage Of N-Substituted Carbamic Acid Ester Comprising N-Substituted Carbamic Acid Ester and Aromatic Hydroxy Compound
  申请人：Shinohata Masaaki

  公开号：US20110133121A1

  公开（公告）日：2011-06-09

  The present invention is a method for producing an N-substituted carbamic acid ester derived from an organic amine from an organic amine, a carbonic acid derivative and a hydroxy composition containing one or more types of hydroxy compounds, wherein the organic amine, the carbonic acid derivative and the hydroxy composition are reacted using a urethane production reaction vessel provided with a condenser, a gas containing the hydroxy composition, the compound having the carbonyl group derived from the carbonic acid derivative, and an ammonia formed as a by-product in the reaction, is introduced into the condenser provided in the urethane production reaction vessel, and the hydroxy composition and the compound having the carbonyl group derived from the carbonic acid derivative are condensed, and wherein a stoichiometric ratio of a hydroxy compound contained in the condensed hydroxy composition to the condensed compound having the carbonyl group derived from the carbonic acid derivative is 1 or more, and a ratio of number of carbonyl groups (—C(═O)—) contained in the compound having the carbonyl group derived from the carbonic acid derivative and number of ammonia molecules contained in the ammonia recovered as a gas from the condenser is 1 or less.

  本发明涉及一种从有机胺、碳酸衍生物和含有一种或多种羟基化合物中制得的N-取代氨基甲酸酯的制备方法，其中使用一种含有冷凝器的脲类生产反应容器反应有机胺、碳酸衍生物和羟基化合物，将含有羟基化合物的气体、来自碳酸衍生物衍生的含有羰基基团的化合物、以及在反应中形成的氨气体引入到脲类生产反应容器中的冷凝器中，使羟基化合物和含有羰基基团的化合物冷凝，其中在冷凝的羟基化合物中所含有的羟基化合物与冷凝的含有羰基基团的化合物中所含有的羰基基团的化合物的比例为1或更多，而且在从冷凝器中回收的氨气体中所含有的羰基基团（—C(═O)—）数与氨分子数的比例为1或更少。
• N-Substituted Carbamic Acid Ester Production Method, Isocyanate Production Method Using Such N-Substituted Carbamic Acid Ester, and Composition for Transfer and Storage of N-Substituted Carbamic Acid Ester Comprising N-Substituted Carbamic Acid Ester and Aromatic Hydroxy Compound
  申请人：Asahi Kasei Chemicals Corporation

  公开号：US20140194650A1

  公开（公告）日：2014-07-10

  The present invention is a method for producing an N-substituted carbamic acid ester derived from an organic amine from an organic amine, a carbonic acid derivative and a hydroxy composition containing one or more types of hydroxy compounds, wherein the organic amine, the carbonic acid derivative and the hydroxy composition are reacted using a urethane production reaction vessel provided with a condenser, a gas containing the hydroxy composition, the compound having the carbonyl group derived from the carbonic acid derivative, and an ammonia formed as a by-product in the reaction, is introduced into the condenser provided in the urethane production reaction vessel, and the hydroxy composition and the compound having the carbonyl group derived from the carbonic acid derivative are condensed, and wherein a stoichiometric ratio of a hydroxy compound contained in the condensed hydroxy composition to the condensed compound having the carbonyl group derived from the carbonic acid derivative is 1 or more, and a ratio of number of carbonyl groups (—C(═O)—) contained in the compound having the carbonyl group derived from the carbonic acid derivative and number of ammonia molecules contained in the ammonia recovered as a gas from the condenser is 1 or less.

  本发明是一种从有机胺、碳酸酯衍生物和含有一种或多种羟基化合物中制备N-取代的氨基甲酸酯的方法，其中利用一种尿素生产反应容器反应有机胺、碳酸酯衍生物和羟基化合物，该反应容器配有冷凝器，将含有羟基化合物的气体、由碳酸酯衍生物产生的含有羰基基团的化合物以及在反应中生成的氨引入到尿素生产反应容器中的冷凝器中，将羟基化合物和含有羰基基团的碳酸酯衍生物冷凝，其中在冷凝的羟基化合物中所含的羟基化合物的化学计量比与所冷凝的含有羰基基团的化合物的化学计量比为1或更多，而且所含有羰基基团的化合物中所含的羰基基团（-C(═O)-）的数量与从冷凝器中回收的氨分子数量的比率为1或更小。
• PROCESS FOR PRODUCING ALPHA, ALPHA- DIFLUOROAMINE
  申请人：National University Corporation Hokkaido University

  公开号：EP1813596A1

  公开（公告）日：2007-08-01

  A process for producing an α,α-difluoroamine which comprises using hydrogen fluoride and a Lewis base in specific amounts in the halogen-fluorine exchange reaction using an α,α-dihaloamine as the substrate. The process can be industrially applied, enables to obtain the object compound in a short time at a great yield and can be conducted easily with excellent productivity.

  一种生产α,α-二氟化胺的工艺，包括在以α,α-二卤胺为底物的卤-氟交换反应中使用一定量的氟化氢和路易斯碱。该工艺可应用于工业，能在短时间内以高产率获得目标化合物，而且操作简便，生产效率极高。