3-amino-2-fluoro-N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethoxy)phenyl)benzamide | 1207315-94-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-amino-2-fluoro-N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethoxy)phenyl)benzamide
• 英文别名: 3-amino-N-[2-bromo-4-[1,1,1,2,3,3,3-heptafluoroprop-2-yl]-6-(trifluoromethoxy)phenyl]-2-fluorobenzamide；N-(2-bromo-4-heptafluoroisopropyl-6-trifluoromethoxyphenyl)-2-fluoro-3-aminobenzamide；3-amino-N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethoxy)phenyl)-2-fluorobenzamide；3-amino-N-[2-bromo-4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-6-(trifluoromethoxy)phenyl]-2-fluorobenzamide
• CAS: 1207315-94-3
• 化学式: C₁₇H₈BrF₁₁N₂O₂
• 分子量: 561.149
• InChiKey: UTFYJIRLQQXZRH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.3
• 重原子数：
  33
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  64.4
• 氢给体数：
  2
• 氢受体数：
  14

反应信息

• 作为反应物：
  描述：

  3-amino-2-fluoro-N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethoxy)phenyl)benzamide 在 聚合甲醛 作用下， 以89%的产率得到N-(2-bromo-4-heptafluoroisopropyl-6-trifluoromethoxyphenyl)-2-fluoro-3-methylaminobenzamide
  参考文献：
  名称：

  PIPERIC ACID DERIVATIVE AND APPLICATION THEREOF

  摘要：

  本发明属于杀虫剂和杀螨剂领域，特别涉及一种对硼酸衍生物及其应用。该化合物的结构如一般式I所示，公式中每个取代基的定义在说明中描述。一般式I的化合物具有优异的杀虫和杀螨活性，可用于控制各种害虫和螨类。

  公开号：

  US20220202011A1
• 作为产物：
  描述：

  2-氟-3-硝基苯甲酸 在 sodium hydroxide 、 氯化亚砜 、 stannous chloride 作用下， 生成 3-amino-2-fluoro-N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethoxy)phenyl)benzamide
  参考文献：
  名称：

  PIPERIC ACID DERIVATIVE AND APPLICATION THEREOF

  摘要：

  本发明属于杀虫剂和杀螨剂领域，特别涉及一种对硼酸衍生物及其应用。该化合物的结构如一般式I所示，公式中每个取代基的定义在说明中描述。一般式I的化合物具有优异的杀虫和杀螨活性，可用于控制各种害虫和螨类。

  公开号：

  US20220202011A1

文献信息

• [EN] PROLONGED ECTOPARASITE-CONTROLLING AGENT FOR ANIMAL<br/>[FR] AGENT DE LUTTE PROLONGÉE CONTRE LES ECTOPARASITES POUR UN ANIMAL
  申请人：MITSUI CHEMICALS AGRO INC

  公开号：WO2019059412A1

  公开（公告）日：2019-03-28

  A compound represented by Formula (1) can be used as a prolonged ectoparasite-controlling agent for an animal. A preparation for systemic application for use in prolonged control of an ectoparasite in an animal include the compound. A method for prolonged control of an ectoparasite on an animal includes systemically applying the compound. The compound may be used for preparing a medicament for prolonged control of an ectoparasite on an animal. A horticultural or agricultural insecticide containing the compound, and a method of protecting a crop from a harmful organism is also provided.

  由式（1）表示的化合物可用作动物长期控制外寄生虫的药剂。用于动物长期控制外寄生虫的系统应用制剂包括该化合物。一种动物长期控制外寄生虫的方法包括系统地应用该化合物。该化合物可用于制备用于动物长期控制外寄生虫的药物。还提供了含有该化合物的园艺或农业杀虫剂，以及一种保护作物免受有害生物侵害的方法。
• Method for preparing an N-cyclopropylmethyl aniline compound
  申请人：Chang Sha Jia Qiao Biotech CO., LTD.

  公开号：US10844005B1

  公开（公告）日：2020-11-24

  Provided is a method for preparing an N-cyclopropylmethyl aniline compound, which comprises reacting a compound represented by Formula IV with cyclopropyl formaldehyde in the presence of metal zinc and an acid to generate an N-cyclopropylmethyl aniline compound represented by Formula I. The method of the present disclosure has mild reaction conditions, short reaction time, a high yield, simple processes, simple operations and low costs, and is more applicable to industrial production.

  本发明提供了一种制备N-环丙基甲基苯胺化合物的方法，其中包括在金属锌和酸的存在下，将公式IV表示的化合物与环丙基甲醛反应，生成公式I表示的N-环丙基甲基苯胺化合物。本发明的方法反应条件温和，反应时间短，产率高，工艺简单，操作简便，成本低，更适用于工业生产。
• AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE
  申请人：Kobayashi Yumi

  公开号：US20110201687A1

  公开（公告）日：2011-08-18

  An amide derivative represented by the following Formula (1) is provided as an amide derivative showing a significantly excellent effect for a pest control action. In the following Formula (1), A represents a carbon atom, a nitrogen atom, or the like, and K represents a non-metal atomic group necessary for forming a cyclic linking group derived from benzene or a heterocyclie. X represents a halogen atom or the like; n represents an integer of from 0 to 4 . R 1 and R 2 represent hydrogen atoms, alkyl groups, or the like. T represents —C(=G 1 )-Q 1 or —C(=G 1 )-G 2 Q 2 , and G 1 to G 3 each represent oxygen atoms or the like. Q 1 and Q 2 each represent a hydrogen atom, an alkyl group, an aryl group, or the like. Y 1 and Y 5 each represent a halogen atom or the like, Y 2 and Y 4 each represent a hydrogen atom or the like, and Y 3 represents a C2-C5 haloalkyl group.

  提供以下式子（1）表示的酰胺衍生物，作为一种表现出显著杀虫作用的酰胺衍生物。在下面的式子（1）中，A代表碳原子、氮原子或类似物，K代表必要的非金属原子团，用于形成从苯或杂环中得到的环链连接基。X代表卤素原子或类似物；n代表0至4的整数。R1和R2代表氢原子、烷基或类似物。T代表- C（= G1）- Q1或- C（= G1）- G2Q2，G1到G3每个代表氧原子或类似物。Q1和Q2每个代表氢原子、烷基、芳基或类似物。Y1和Y5每个代表卤素原子或类似物，Y2和Y4每个代表氢原子或类似物，Y3代表C2-C5卤代烷基。
• Amide derivative, pest control agent containing the amide derivative, and use of the amide derivative
  申请人：Kobayashi Yumi

  公开号：US08686044B2

  公开（公告）日：2014-04-01

  An amide derivative represented by the following Formula (1) is provided as an amide derivative showing a significantly excellent effect for a pest control action. In the following Formula (1), A represents a carbon atom, a nitrogen atom, or the like, and K represents a non-metal atomic group necessary for forming a cyclic linking group derived from benzene or a heterocyclie. X represents a halogen atom or the like; n represents an integer of from 0 to 4. R1 and R2 represent hydrogen atoms, alkyl groups, or the like. T represents —C(=G1)-Q1 or —C(=G1)-G2Q2, and G1 to G3 each represent oxygen atoms or the like. Q1 and Q2 each represent a hydrogen atom, an alkyl group, an aryl group, or the like. Y1 and Y5 each represent a halogen atom or the like, Y2 and Y4 each represent a hydrogen atom or the like, and Y3 represents a C2-C5 haloalkyl group.

  提供了一种由以下公式（1）表示的酰胺衍生物，作为显示显著卓越的杀虫作用的酰胺衍生物。在下述公式（1）中，A代表碳原子、氮原子或类似物，K代表必要的非金属原子团，以形成从苯或杂环中导出的环状连接基。X代表卤素原子或类似物；n代表0到4的整数。R1和R2代表氢原子、烷基或类似物。T代表-C（=G1）-Q1或-C（=G1）-G2Q2，G1至G3各自代表氧原子或类似物。Q1和Q2各自代表氢原子、烷基、芳基或类似物。Y1和Y5各自代表卤素原子或类似物，Y2和Y4各自代表氢原子或类似物，Y3代表C2-C5卤代烷基。
• AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE AND USE OF THE PEST CONTROL AGENT
  申请人：Mitsui Chemicals Agro, Inc.

  公开号：EP2319830A1

  公开（公告）日：2011-05-11

  An amide derivative represented by the following Formula (1) is provided as an amide derivative showing a significantly excellent effect for a pest control action. In the following Formula (1), A represents a carbon atom, a nitrogen atom, or the like, and K represents a non-metal atomic group necessary for forming a cyclic linking group derived from benzene or a heterocyclie. X represents a halogen atom or the like; n represents an integer of from 0 to 4. R1 and R2 represent hydrogen atoms, alkyl groups, or the like. T represents -C(=G1)-Q1 or -C(=G1)-G2Q2, and G1 to G3 each represent oxygen atoms or the like. Q1 and Q2 each represent a hydrogen atom, an alkyl group, an aryl group, or the like. Y1 and Y5 each represent a halogen atom or the like, Y2 and Y4 each represent a hydrogen atom or the like, and Y3 represents a C2-C5 haloalkyl group.

  下式(1)代表的酰胺衍生物作为一种酰胺衍生物，在害虫防治方面具有显著的优异效果。 在下式（1）中，A 代表碳原子、氮原子或类似物，K 代表形成源自苯或杂环的环状连接基团所必需的非金属原子团。X 代表卤素原子或类似物；n 代表 0 至 4 的整数。R1 和 R2 代表氢原子、烷基或类似物。T 代表 -C(=G1)-Q1 或 -C(=G1)-G2Q2，G1 至 G3 各自代表氧原子或类似物。Q1 和 Q2 各自代表氢原子、烷基、芳基或类似物。Y1 和 Y5 分别代表卤原子或类似物，Y2 和 Y4 分别代表氢原子或类似物，Y3 代表 C2-C5 卤代烷基。