1-methyl-2-(propan-1'-ylsulfanyl)benzene | 15560-97-1

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 1-methyl-2-(propan-1'-ylsulfanyl)benzene
• 英文别名: propyl-o-tolyl sulfide；Propyl-o-tolyl-sulfid；Benzene, methyl(propylthio)-；1-methyl-2-propylsulfanylbenzene
• CAS: 15560-97-1
• 化学式: C₁₀H₁₄S
• 分子量: 166.287
• InChiKey: OAKIXGDEEBCTQM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  25.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1-methyl-2-(propan-1'-ylsulfanyl)benzene 在 盐酸 、 sodium hydroxide 、 potassium hydrosulfide 、 zinc(II) chloride 作用下， 生成 (3-Methyl-4-propylmercapto-benzyl)-propyl-thioether
  参考文献：
  名称：

  Profft,E.; Steinbach,H.-J., Chemische Berichte, 1961, vol. 94, p. 151 - 157

  摘要：

  DOI：
• 作为产物：
  描述：

  邻甲苯磺酰氯 在 盐酸 、 sodium hydroxide 、 铁粉 作用下， 生成 1-methyl-2-(propan-1'-ylsulfanyl)benzene
  参考文献：
  名称：

  Profft, Chemische Technik, 1953, vol. 5, p. 239,241

  摘要：

  DOI：

文献信息

• Studies in the Cycloproparene Series: Reactions With Radicals
  作者：CLL Chai、D Christen、B Halton、R Neidlein、MAE Starr

  DOI：10.1071/ch9950577

  日期：——

  The behaviour of 1H-cyclopropabenzene (1) and 1H-cyclopropa[b]naphthalene (23) towards a variety of radicals results in opening of the three- membered ring to give ortho -substituted benzyl and 2-methylnaphthalene derivatives, e.g. (13) and (28), respectively. Ring expansion into the cycloheptatriene manifold by way of addition to the bridge bond and norcaradiene formation have not been observed. Analogous reactions with the methylidenecyclopropa [b] naphthalenes (33) and (34) lead to much decomposition, and provide little evidence for the C1cycloproparenyl radicals (35) and (36).

  1H- 环丙基苯 (1) 和 1H- 环丙[b]萘 (23) 对各种自由基的作用结果是打开三位环，分别生成正交取代的苄基和 2-甲基萘衍生物，如 (13) 和 (28)。还没有观察到通过桥键加成的方式将环扩展到环庚三烯歧管和形成芴的情况。与亚甲基环丙[b]萘（33）和（34）的类似反应会导致大量分解，而 C1 环丙烯基（35）和（36）则没有提供多少证据。
• Enantioselective Nitrene Transfer to Sulfides Catalyzed by a Chiral Iron Complex
  作者：Jun Wang、Marcus Frings、Carsten Bolm

  DOI：10.1002/anie.201304451

  日期：2013.8.12

  Iron works: Enantioselective nitrene transfer to sulfide was accomplished by a chiral iron(III)/PyBOX catalyst (see scheme). Various sulfimides were thus obtained in high enantioselectivities and yields. Applications of this protocol to the syntheses of enantioenriched sulfoximines and an epoxide were also demonstrated.

  铁厂：通过手性铁（III）/ PyBOX催化剂（参见方案）可实现对映选择性的腈转化为硫化物。因此以高对映选择性和产率获得了各种磺酰亚胺。还证明了该方案在对映体富集的亚砜亚胺和环氧化物的合成中的应用。
• [EN] SULFONE DERIVATIVES<br/>[FR] DÉRIVÉS DE SULFONE
  申请人：HOFFMANN LA ROCHE

  公开号：WO2021259831A1

  公开（公告）日：2021-12-30

  The present invention provides compounds of formula (I) wherein X1, X2, X3, X4, R1, R1a, R1b, R2', R2", R3', R3", R6 and R7 are as described herein, as well as pharmaceutically acceptable salts thereof. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments.

  本发明提供了化合物的结构式(I)，其中X1、X2、X3、X4、R1、R1a、R1b、R2'、R2"、R3'、R3"、R6和R7如本文所述，以及其药学上可接受的盐。此外，本发明涉及制备结构式(I)化合物、包含它们的药物组合物以及它们作为药物的用途。
• AZOLYLMETHYLIDENEHYDRAZINE DERIVATIVE AND USE THEREOF
  申请人：Ogura Hironobu

  公开号：US20100190754A1

  公开（公告）日：2010-07-29

  An azolylmethylidenehydrazine derivative represented by the formula (I) wherein Ar is an aryl group optionally having substituent(s) or a heteroaryl group optionally having substituent(s), R 1 and R 2 are the same or different and each is an alkyl group, a cycloalkyl group, an aralkyl group optionally having substituent(s), an aryl group optionally having substituent(s), a heteroarylalkyl group optionally having substituent(s), or R 1 and R 2 are bonded to each other to form a nitrogen-containing heterocyclic group optionally having substituent(s), and X is CH or a nitrogen atom, or a pharmacologically acceptable salt thereof is useful as a medicament, particularly as an antifungal agent, or an anti-inflammatory agent or an antiallergic agent.

  一种以式(I)表示的氮杂环甲基亚唑啉衍生物，其中Ar是一个芳基基团，可选择地具有取代基，或者是一个杂芳基基团，可选择地具有取代基；R1和R2相同或不同，每个都是一个烷基基团、环烷基基团、可选择地具有取代基的芳基烷基基团、可选择地具有取代基的芳基基团、可选择地具有取代基的杂芳基烷基基团，或者R1和R2彼此连接形成一个可选择地具有取代基的含氮杂环基团；X是CH或氮原子；或其药学上可接受的盐，可用作药物，特别是作为抗真菌药物、抗炎药物或抗过敏药物。
• Photosensitive resin composition, light-shielding color filter and production process therefor, and image sensor
  申请人：FUJIFILM Corporation

  公开号：EP2105792A1

  公开（公告）日：2009-09-30

  A photosensitive resin composition is provided that includes at least (A) titanium black, (B) two or more types of polymerizable compounds, (C) a resin, (D) a photopolymerization initiator, and (E) an organic solvent. There are also provided a light-shielding color filter formed by using the photosensitive resin composition, and a process for producing a light-shielding color filter, the process including a step of coating a substrate with the photosensitive resin composition, a step of imagewise exposing, and a step of developing to form a pattern. Furthermore, there is provided an image sensor that includes the light-shielding color filter.

  提供了一种光敏树脂组合物，它至少包括 (A) 钛黑、(B) 两种或两种以上的可聚合化合物、(C) 树脂、(D) 光聚合引发剂和 (E) 有机溶剂。此外，还提供了一种通过使用感光树脂组合物形成的遮光彩色滤光片，以及一种生产遮光彩色滤光片的工艺，该工艺包括用感光树脂组合物涂覆基底的步骤、图像曝光步骤，以及显影以形成图案的步骤。此外，还提供了一种包括遮光彩色滤光片的图像传感器。