4-(diphenylmethyl)aniline | 603-38-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• 英文名称: 4-(diphenylmethyl)aniline
• 英文别名: 4-benzhydrylaniline
• CAS: 603-38-3
• 化学式: C₁₉H₁₇N
• 分子量: 259.351
• InChiKey: IVKMZPOWNVXFFH-UHFFFAOYSA-N

物化性质

• 熔点：
  84.5°C
• 沸点：
  392.6°C (rough estimate)
• 密度：
  0.9242 (rough estimate)

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  1

安全信息

• 危险性防范说明：
  P261,P264,P271,P280,P302+P352,P304+P340,P305+P351+P338,P312,P362,P403+P233,P501
• 危险性描述：
  H315,H319,H335

反应信息

• 作为反应物：
  描述：

  4-(diphenylmethyl)aniline 在 硝酸 、 溶剂黄146 、 sodium nitrite 作用下， 以 1,4-二氧六环 、 乙醇 、 水 为溶剂， 反应 7.0h， 生成 4-(4-Methylphenylazo)triphenylmethanol
  参考文献：
  名称：

  Hellwinkel, Dieter; Fritsch, Helmut, Chemische Berichte, 1990, vol. 123, # 11, p. 2207 - 2226

  摘要：

  DOI：
• 作为产物：
  描述：

  1-(diphenylmethyl)-4-nitrobenzene 在 palladium on activated charcoal 、 氢气 作用下， 以 乙醇 为溶剂， 以91.2%的产率得到4-(diphenylmethyl)aniline
  参考文献：
  名称：

  用光开关 Eg5 抑制剂对有丝分裂进行光学控制

  摘要：

  有丝分裂驱动蛋白 Eg5 的光学控制是通过 EMD-534085 的偶氮苯类似物实现的。在紫外线条件下，HeLa 细胞发生有丝分裂停滞，单极纺锤体的形成证明了这一点。

  DOI：

  10.1002/anie.202115846

文献信息

• [EN] TRANSITION METAL COMPOUNDS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION<br/>[FR] COMPOSES METALLIQUES DE TRANSITION POUR LA POLYMERISATION D'OLEFINES ET L'OLIGOMERISATION
  申请人：EXXONMOBIL CHEM PATENTS INC

  公开号：WO2005118605A1

  公开（公告）日：2005-12-15

  This invention relates to new transition metal catalyst compounds represented by the formula (I): where: M and M' are, independently, a group 8, 9, 10 or 11 transition metal, preferably Ni, Co, Pd, Cu or Fe; each R group is, independently, is, hydrogen, or a hydrocarbyl, substituted hydrocarbyl, halocarbyl, substituted halocarbyl, silylcarbyl, substituted silylcarbyl, germylcarbyl, or substituted germylcarbyl substituents, and optionally, adjacent R groups may join together to form a substituted or unsubstituted, saturated, partially unsaturated, or aromatic cyclic or polycyclic substituent; R' is hydrogen, or a hydrocarbyl, substituted hydrocarbyl, halocarbyl, substituted halocarbyl, silylcarbyl, substituted silylcarbyl, germylcarbyl, or substituted germylcarbyl substituents, and optionally, adjacent R groups may join together with R' to form a substituted or unsubstituted, saturated, partially unsaturated, or aromatic cyclic or polycyclic substituent; each X group is, independently, is, hydrogen, a halogen, or a hydrocarbyl, substituted hydrocarbyl, halocarbyl, substituted halocarbyl, silylcarbyl, substituted sililcarbyl, germylcarbyl, or substituted germylcarbyl substituents, and optionally, adjacent X groups may join together to form a substituted or unsubstituted, saturated, partially unsaturated, or aromatic cyclic or polycyclic substituent; m and m’ are, independently, 0, 1, 2, or 3; z and z’ are, independently, 0, 1, 2, or 3; N is nitrogen; Q is hydrogen, or a hydrocarbyl, substituted hydrocarbyl, halocarbyl, substituted halocarbyl, silylcarbyl, substituted silylcarbyl, germylcarbyl, or substituted germylcarbyl substituents; Q’ is hydrogen, or a hydrocarbyl, substituted hydrocarbyl, halocarbyl, substituted halocarbyl, silylcarbyl, substituted silylcarbyl, germylcarbyl or substituted germylcarbyl substituents; and L is a hydrocarbyl, substituted hydrocarbyl, halocarbyl, substituted halocarbyl, silylcarbyl, substituted silylcarbyl, germylcarbyl, or substituted germylcarbyl substituent.

  这项发明涉及由式(I)表示的新过渡金属催化剂化合物，其中：M和M'分别是8、9、10或11族过渡金属，优选为Ni、Co、Pd、Cu或Fe；每个R基分别是氢，或烃基，取代烃基，卤代烃基，取代卤代烃基，硅烃基，取代硅烃基，锗烃基，或取代锗烃基取代基，且可选地，相邻的R基可以结合在一起形成取代或未取代的饱和、部分不饱和或芳香环或多环取代基；R'是氢，或烃基，取代烃基，卤代烃基，取代卤代烃基，硅烃基，取代硅烃基，锗烃基，或取代锗烃基取代基，且可选地，相邻的R基可以与R'结合在一起形成取代或未取代的饱和、部分不饱和或芳香环或多环取代基；每个X基分别是氢，卤素，或烃基，取代烃基，卤代烃基，取代卤代烃基，硅烃基，取代硅烃基，锗烃基，或取代锗烃基取代基，且可选地，相邻的X基可以结合在一起形成取代或未取代的饱和、部分不饱和或芳香环或多环取代基；m和m'分别为0、1、2或3；z和z'分别为0、1、2或3；N为氮；Q为氢，或烃基，取代烃基，卤代烃基，取代卤代烃基，硅烃基，取代硅烃基，锗烃基，或取代锗烃基取代基；Q'为氢，或烃基，取代烃基，卤代烃基，取代卤代烃基，硅烃基，取代硅烃基，锗烃基，或取代锗烃基取代基；L为烃基，取代烃基，卤代烃基，取代卤代烃基，硅烃基，取代硅烃基，锗烃基，或取代锗烃基取代基。
• Nucleophilic Substitution Reactions of Alcohols with Use of Montmorillonite Catalysts as Solid Brønsted Acids
  作者：Ken Motokura、Nobuaki Nakagiri、Tomoo Mizugaki、Kohki Ebitani、Kiyotomi Kaneda

  DOI：10.1021/jo070416w

  日期：2007.8.1

  a variety of alcohols with anilines, because the unique acidity of the H-mont catalyst effectively prevents the neutralization by the basic anilines. In addition, amides, indoles, 1,3-dicarbonyl compounds, and allylsilane act as nucleophiles for the H-mont-catalyzed substitutions of alcohols, which allowed efficient formation of various C−N and C−C bonds. The solid H-mont was reusable without any appreciable

  我们已经开发出一种对醇类进行亲核取代反应的环境友好型合成方法，该方法可最大程度减少或消除副产物的形成，从而实现高度原子效率的化学过程。质子和金属交换的蒙脱石（H和M n+ -mont）由处理的Na容易地制备+用的分别氯化氢或金属盐，水溶液-mont。H-mont具有出色的催化活性，可用于多种醇与苯胺的亲核取代反应，因为H-mont催化剂的独特酸度可有效防止碱性苯胺的中和。另外，酰胺，吲哚，1,3-二羰基化合物和烯丙基硅烷充当H-mont催化的醇取代的亲核试剂，从而可以有效地形成各种CN和CC键。固体H-mont可重复使用，其催化活性和选择性没有任何明显的损失。特别是Al 3+-mont由于在其层间空间中质子酸位点和路易斯酸性Al 3+物种之间的协同催化作用，对伯醇对1,3-二羰基化合物的α-苄基化反应具有较高的催化活性。
• Improving the “darkness to light” ratio in user‐related information retrieval research
  作者：Nigel Ford

  DOI：10.1108/eum0000000007134

  日期：2000.12.1

  Research into information retrieval (IR) cannot yet answer the basic question of how we can design IR systems to help people search for information with optimal levels of effectiveness. In relation to human‐system interaction, we have failed to develop any valid and at the same time robust user models capable of driving practical system development. If we strip away assumptions and over‐optimism relating to the generalisability of what are essentially sporadic and fragmented research efforts, the great “darkness to light” ratio characterising our knowledge of human aspects of IR becomes apparent. From a more critical and pessimistic (but by no means less realistic) perspective, we are getting nowhere fast. A range of strategies is proposed to improve the situation by supporting relatively “horizontal” as well as “vertical” knowledge integration. These consist of: greater use of pluralistic research approaches; enhanced access to research data; more multidisciplinary and multi‐perspective integrative reviews and conceptual mappings; and establishing a greater critical mass of published research findings sufficient to support the generation of a less sparse and fragmented evidence‐based knowledge map. The potential of electronic publishing and data access for helping achieve these goals is discussed.

  对信息检索（IR）的研究还无法回答这样一个基本问题：我们如何才能设计出IR系统，帮助人们以最佳效率搜索信息。在人与系统的交互方面，我们未能开发出任何有效的、同时也是强大的用户模型，来推动实际系统的开发。如果我们撇开对本质上零星分散的研究工作的普遍性的假设和过度乐观，我们对红外人机交互知识的巨大 "从黑暗到光明 "的比率就显而易见了。从更加批判和悲观（但绝不是不那么现实）的角度来看，我们正在迅速取得进展。我们提出了一系列战略，通过支持相对 "横向 "和 "纵向 "的知识整合来改善这种状况。这些战略包括：更多地使用多元化研究方法；加强对研究数据的获取；更多的多学科和多角度综合审查和概念映射；以及建立一个更大的已发表研究成果临界量，足以支持生成一个不那么稀疏和零散的循证知识图谱。本文讨论了电子出版和数据访问在帮助实现这些目标方面的潜力。
• Photoinduced Arene C−H Amination with Ammonia: A Practical and Regioselective Strategy for Primary Amines
  作者：Xiaobin Tan、Wenfang Xiong、Baiyao Zhu、Hongjian Liu、Wanqing Wu、Huanfeng Jiang

  DOI：10.1002/adsc.202300384

  日期：2023.7.4

  chemistry, particularly for the pharmaceuticals and agrochemicals chemistry. Herein, we describe a photoinduced direct C−H amination of arenes with ammonia via the site-selective C−H thianthrenation that forms a new C−N bond with excellent regioselectivity. The reaction is carried out under mild conditions, and with a wide range of functional group tolerance, such as sensitive −Cl, −Br, and −OH groups

  将伯氨基引入芳环是有机化学特别是药物和农药化学中最重要的研究问题之一。在此，我们描述了芳烃与氨的光诱导直接 C−H 胺化，通过位点选择性的 C−H 噻蒽化作用，形成具有优异区域选择性的新的 C−N 键。该反应在温和的条件下进行，具有广泛的官能团耐受性，例如敏感的-Cl、-Br和-OH基团，这些基团在传统方法中耐受性较差。此外，我们的胺化方案的合成效用已通过复杂类药物分子的后期修饰和克级合成得到证实。
• Surface treatment of polyimide film and polyimide film having a thin metal layer
  申请人：UBE INDUSTRIES, LTD.

  公开号：US20020177000A1

  公开（公告）日：2002-11-28

  A method of surface treating a polyimide film to impart improved adhesion to metal which comprises treating the surface of a polyimide film having a biphenyltetracarboxylic acid component by contact to a solution containing potassium permanganate and/or sodium permanganate and potassium hydroxide and/or sodium hydroxide and treating said surface with an acid.

  一种对聚酰亚胺薄膜进行表面处理以提高其对金属的附着力的方法，包括通过接触含有高锰酸钾和/或高锰酸钠以及氢氧化钾和/或氢氧化钠的溶液，并用酸处理具有联苯四羧酸成分的聚酰亚胺薄膜的表面。