甲酮,(反-4-氨基-4-甲基环己基)-4-吗啉基- | 94166-75-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• 中文名称: 甲酮,(反-4-氨基-4-甲基环己基)-4-吗啉基-
• 中文别名: 4-(双(4-(乙基氨基)-3-甲基苯基)甲基)苯-1,3-二磺酸
• 英文名称: 4-(Bis(4-(ethylamino)-3-methylphenyl)methyl)benzene-1,3-disulphonic acid
• 英文别名: 4-[bis[4-(ethylamino)-3-methylphenyl]methyl]benzene-1,3-disulfonic acid
• CAS: 94166-75-3
• 化学式: C₂₅H₃₀N₂O₆S₂
• 分子量: 518.6
• InChiKey: RTUBHMZPHXKJST-UHFFFAOYSA-N

物化性质

• 熔点：
  >300 °C(lit.)
• 密度：
  1.355±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  35
• 可旋转键数：
  9
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.28
• 拓扑面积：
  150
• 氢给体数：
  4
• 氢受体数：
  8

安全信息

• 危险品标志：
  Xi
• 安全说明：
  S26,S36
• 危险类别码：
  R36/37/38

文献信息

• Method for detecting Candida on skin
  申请人：Martin Stephanie

  公开号：US20080057532A1

  公开（公告）日：2008-03-06

  A method and system for rapidly detecting Candida on the skin of a host, such as an infant with diaper rash, is provided. The method includes contacting a dermal sample with a colorant that exhibits a certain spectral response (e.g., color change) in the presence of Candida . For example, the colorant may change from a first color to a second color, from colorless to a color, or from a color to colorless. The colorant is typically capable of differentiating between Candida (e.g., Candida albicans ) and other microorganisms commonly associated with diaper rash, such as S. aureus and E. coli . Thus, when a dermal sample is placed into contact with the colorant, the color change may simply be observed to determine whether the infection is caused by Candida . If the color change occurs to a certain extent (e.g., from yellow to bright red), it may be determined that the test sample contains Candida . Likewise, if a color change occurs to a lesser extent (e.g., from yellow to faint orange) or not at all, it may be determined that the dermal sample contains other microorganisms (e.g., S. aureus or E. coli ), no infection is present, or that the infection is simply due to other causes. Regardless, it will become readily apparent whether or not treatment for Candida is needed.
• Array for rapid detection of a microorganism
  申请人：Martin Stephanie M.

  公开号：US20080057533A1

  公开（公告）日：2008-03-06

  A method for detecting a microorganism or class of microorganisms is provided. More specifically, the method employs an array that contains a plurality of discrete regions (referred to as “addresses”) spaced apart on a solid support in a predetermined pattern. The addresses are selected so that the array provides a distinct spectral response (e.g., pattern of colors) or “fingerprint” for a particular microorganism or class of microorganisms. For example, the array may provide a certain spectral response in the presence of one microorganism or class of microorganisms (e.g., gram-negative bacteria), but provide a completely different spectral response in the presence of another microorganism or class of microorganisms (e.g., gram-positive bacteria). Detection of the spectral response provided by the array may thus allow for differentiation between microorganisms.
• Colorant compositions
  申请人：Stephens B. Eric

  公开号：US20080108817A1

  公开（公告）日：2008-05-08

  Colorant compositions are useful for a wide variety of product applications. For example, colorants are used in tinting of polymers, providing colors to aqueous solution(s), and affording color to solid or semi-solid products such as detergents. Disclosed herein are colorant compositions having a triphenylmethane (“TPM”) structure having improved stability to alkaline conditions. Thus, the colorant compositions resist decolorization, even at relatively high pH levels.
• Skin coating with microbial indicator
  申请人：MacDonald John Gavin

  公开号：US20080145316A1

  公开（公告）日：2008-06-19

  Skin sealants are usually applied over skin preps to seal the skin and hold any remaining bacteria in place prior to surgical incisions. This sealant is generally left on the skin after surgery. A skin coating is provided that has an indicator that gives a visible color change upon contact with microbes or microbial by-products and so provides an early warning of infection. The coating is a curable coating composition that may also be used without skin preps and may be used to protect other disruptions in the skin like wounds, bruises, abrasions, burns, acne, blisters, bites, stings, punctures and cuts. It may also be used to close wounds or provide an additional barrier to other parts of the skin, such as the nails and mucosa.
• RAPID ASSESSMENT OF UPPER RESPIRATORY CONDITIONS
  申请人：Martin Stephanie M.

  公开号：US20090111088A1

  公开（公告）日：2009-04-30

  A method for rapidly assessing upper respiratory conditions is provided. More specifically, the method involves contacting a sample obtained from the upper respiratory tract of a host with a test strip. The test strip contains an indicator that provides a broad spectrum response in the presence of bacteria, mold, yeast, or other microorganisms that is different than its response in the presence of viruses. This allows for a rapid and simple assessment as to whether the test sample is infected with a virus or some other microorganism. To help a clinician identify the proper course of treatment, it may also be desirable to obtain further information about the particular type of microorganism present. In this regard, the test strip contains any array of one or more differentiating indicators that provides a certain spectral response in the presence of different types of microorganisms. For example, the array may provide a certain spectral response in the presence of gram-negative bacteria, but a completely different spectral response in the presence of gram-positive bacteria. Likewise, the array may provide a certain spectral response in the presence of Rhinoviruses (associated with the common cold), but a different response in the presence of Influenza viruses. Detection of the spectral response provided by the indicators may thus allow for rapid differentiation between different types of microorganisms.