S-tert-butyl 2,2-dimethyl-thiopropanoate | 28058-96-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 硫代羧酸及其衍生物
• 英文名称: S-tert-butyl 2,2-dimethyl-thiopropanoate
• 英文别名: S-tert-butyl 2,2-dimethylthiopropanoate；2,2-Dimethyl-thiopropionsaeure-S-tert-butylester；Trimethylthioessigsaeure-S-t-butylester；tert-Butyl-thiol-pivalat；S-tert-butyl 2,2-dimethylpropanethioate
• CAS: 28058-96-0
• 化学式: C₉H₁₈OS
• 分子量: 174.307
• InChiKey: XIVRWHDGSKWXQZ-UHFFFAOYSA-N

物化性质

• 沸点：
  101-103 °C(Press: 21 Torr)
• 密度：
  0.925±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  42.4
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  S-tert-butyl 2,2-dimethyl-thiopropanoate 、 叔丁醇 在 mercury(II) methanesulfonate 作用下， 生成 特戊酸叔丁酯
  参考文献：
  名称：

  硫醇酯的活化。细胞松弛素A和B的部分合成。

  摘要：

  DOI：

  10.1021/ja00462a049
• 作为产物：
  描述：

  tert.-Butyl-thiolcarbons.anhydr. 在 三乙胺 作用下， 生成 S-tert-butyl 2,2-dimethyl-thiopropanoate
  参考文献：
  名称：

  Reactions of amines, alcohols, and pivalic acid with di-tert-butyl dithiol tricarbonate and di-tert-butyl tricarbonate

  摘要：

  DOI：

  10.1021/jo00808a003

文献信息

• MONOMER, POLYMER, RESIST COMPOSITION, AND PATTERNING PROCESS
  申请人：SHIN-ETSU CHEMICAL CO., LTD.

  公开号：US20150322027A1

  公开（公告）日：2015-11-12

  A monomer (1) is prepared by reacting a compound (9) with a base or metal to form a metal enolate reagent, and reacting the metal enolate reagent with an acyloxyketone compound (8). A polymer derived from the monomer is used as base resin to formulate a resist composition, which is shelf stable and displays a high dissolution contrast, controlled acid diffusion and low roughness in forming positive pattern via alkaline development and in forming negative pattern via organic solvent development.

  一种单体（1）是通过将一种化合物（9）与碱或金属反应形成金属烯醇盐试剂，然后将金属烯醇盐试剂与一种酰氧基酮化合物（8）反应而制备的。由该单体派生出的聚合物用作基础树脂，以配制一种光刻胶组合物，该组合物在常温下稳定，显示出高溶解对比度、控制的酸性扩散和在碱性显影形成正图案以及有机溶剂显影形成负图案时低粗糙度。
• Activation of mixed carboxylic α-bromotoluoyl anhydrides by silver tetraflouroborate. Synthesis of ester and thiol esters
  作者：Satoshi Fukuoka、Seiji Takimoto、Tsutomu Katsuki、Masaru Yamaguchi

  DOI：10.1016/s0040-4039(00)96605-x

  日期：1987.1

  Mixed carboxylic α-bromotoluoyl anhydrides were activated by silver tetrafluoroborate through intramolecular cyclization and reacted with alcohols or thiols giving the corresponding esters or thiol esters in good yileds with the elimination of phthalide.

  四氟硼酸银通过分子内环化作用活化了混合的羧酸α-溴代甲酰酐酸酐，并与醇或硫醇反应生成了相应的酯或硫醇酯，从而获得了良好的产率，并且消除了邻苯二甲酰胺。
• A convenient one-pot procedure for synthesis of thiol esters using magnesium ion as a catalyst
  作者：Shunsaku Ohta、Masao Okamoto

  DOI：10.1016/s0040-4039(01)81874-8

  日期：1981.1

  Various thiol esters (R1 COSR2) were prepared in high yields by treatment of 1-acylimidazole with thiols in the presence of a catalytic amount of Mg(OEt)2. Malonic half-thiol esters [R1OCOCH(R3)COSR2] were also prepared in good yields by treating magnesium monoalkyl malonate [R1 OCOCH(R3)COOMg12] with carbonyl-1,1′-diimidazole followed by addition of thiols.

  在催化量的Mg（OEt）2存在下，通过用硫醇处理1-酰基咪唑，可以高收率制备各种硫醇酯（R 1 COSR 2）。还可以通过用羰基-1,1'-二咪唑处理丙二酸单烷基丙二酸镁[R 1 OCOCH（R 3）COOMg12]，然后以高收率制备丙二酸半硫醇酯[R 1 OCOCH（R 3）COSR 2 ] 。硫醇。
• Synthesis of Thiol Esters by Carboxylic Trichlorobenzoic Anhydrides
  作者：Yasuhiro Kawanami、Yuichiro Dainobu、Junji Inanaga、Tsutomu Katsuki、Masaru Yamaguchi

  DOI：10.1246/bcsj.54.943

  日期：1981.3

  Thiocarboxylic S-esters were obtained rapidly and in high yields by treating the mixed anhydrides prepared from 2,4,6-trichlorobenzoyl chloride and carboxylic acid, with various types of thiols in the presence of 4-dimethylaminopyridine.

  通过将2,4,6-三氯苯甲酰氯和羧酸制备的混合酸酐与各种类型的硫醇在4-二甲氨基吡啶存在下进行处理，快速且高收率地获得了硫代羧酸S-酯。
• Preparation of 4-[alkyl-(or aryl)-thio-substituted]-1,4-dihydropyridines and their use as thiolate-transferring agents
  作者：Oscar Piepers、Richard M. Kellogg

  DOI：10.1039/c39800001147

  日期：——

  Alkane-(or arene)-thiols or thiolates add smoothly to esters or amides of 1-methylpyridinium-3,5-dicarboxylic acid salts; on treatment of these adducts with activated acid-derivatives, thioesters are formed in excellent yields.

  烷烃-（或芳烃）-硫醇或硫醇盐可平滑地添加到1-甲基吡啶-3,5-二羧酸盐的酯或酰胺中；用活化的酸衍生物处理这些加合物时，硫代酸酯的形成得率极高。