N-Methyl-N',N''-diphenylguanidin | 35210-65-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-Methyl-N',N''-diphenylguanidin
• 英文别名: 1-Methyl-2,3-diphenylguanidin；N-methyl-N',N''-diphenyl-guanidine；N-Methyl-N',N''-diphenyl-guanidin；N,N'-Diphenyl-N''-methyl-guanidin；2-Methyl-1,3-diphenylguanidine
• CAS: 35210-65-2
• 化学式: C₁₄H₁₅N₃
• 分子量: 225.293
• InChiKey: JBTSVGBEJFWROG-UHFFFAOYSA-N

物化性质

• 熔点：
  109 °C
• 沸点：
  348.5±25.0 °C(Predicted)
• 密度：
  1.05±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  36.4
• 氢给体数：
  2
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  N-Methyl-N',N''-diphenylguanidin 、 氯羰基亚磺酰氯 在 三乙胺 作用下， 以 四氢呋喃 为溶剂， 反应 1.0h， 以47%的产率得到2-methyl-4-phenyl-3-phenylimino-1,2,4-thiadiazolidin-5-one
  参考文献：
  名称：

  Cycloadditions-Eliminierungsreaktionen von Phenylisocyanat mit Oxo-und Thionoderivaten aliphatisch substituierter 5-Imino-1,2,4-dithiazolidine und 3-Thiono-1,2,4-thiadiazolidine (Senf�loxide und Senf�lsulfide)

  摘要：

  5-Imino-1,2,4-dithiazolidin-3-ones 1 and -3-thiones 3 react with phenylisocyanate to afford 5-imino-1,2,4-thiadiazolidin-3-ones 6. In comparison isomeric 3-thiono-1,2,4-thiadiazolidin-5-ones 2, 5, and -5-thiones 4 yield 3-imino-1,2,4-thiadiazolidin-5-ones 8, 10, and -5-thiones 7. Thermolyses of thiadiazolidines 5 and 10 afford further 1,2,4-thiadiazolidines 9, 11. Compounds 8 - 11 are available also by reaction of substituted guanidines with chlorocarbonyl sulfenylchloride.

  DOI：

  10.1002/prac.19923340808
• 作为产物：
  描述：

  1-甲基-4-苯基四唑-5-硫酮 以 六甲基磷酰三胺 、 二氯甲烷 为溶剂， 反应 73.0h， 生成 N-Methyl-N',N''-diphenylguanidin
  参考文献：
  名称：

  Quast, Helmut; Fuss, Andreas; Nahr, Uwe, Chemische Berichte, 1985, vol. 118, # 6, p. 2164 - 2185

  摘要：

  DOI：

文献信息

• CATALYSTS AND METHODS FOR POLYMER SYNTHESIS
  申请人：NOVOMER, INC.

  公开号：US20130144032A1

  公开（公告）日：2013-06-06

  The present invention provides unimolecular metal complexes having increased activity in the copolymerization of carbon dioxide and epoxides. Also provided are methods of using such metal complexes in the synthesis of polymers. According to one aspect, the present invention provides metal complexes comprising an activating species with co-catalytic activity tethered to a multidentate ligand that is coordinated to the active metal center of the complex.

  本发明提供了在二氧化碳和环氧化物的共聚合中具有增强活性的单分子金属配合物。还提供了使用这种金属配合物在合成聚合物中的方法。根据一个方面，本发明提供了包括与具有共催化活性的活化物种相耦合的多齿配体的金属配合物，该多齿配体与复合物的活性金属中心配位。
• N-phosphonomethylglycine derivatives
  申请人：Geshuri Laboratories Ltd.

  公开号：EP0088180A1

  公开（公告）日：1983-09-14

  The invention provides N-Phosphonomethylglycine derivatives of the general formula I wherein R,, R2 and R3 are independently selected from-OH and -OR4 wherein R4 is a salt forming cation iminourea derivative of the general formula II wherein R5, R5, R6, R6, and R7 are independently H, NH2, or an aryl, cycloalkyl or straight or branched chain alkyl or alkenyl group optionally substituted by hydroxy or halogen, or an alkylaryl group, provided that at least one but no more than two of R,, R2 or R3 are OR4; no more than two R5, R5, R6, R6, are aryl or substituted aryl; and no more than one of R5, R5., R6, R6, and R, is CH2OH. The invention also provides a process for preparing the above N-Phosphonomethylglycine imino urea salts as well as providing phytotoxic compositions containing the same.

  本发明提供通式 I 的 N-膦酰甲基甘氨酸衍生物 其中 R、R2 和 R3 独立地选自-OH 和-OR4，其中 R4 是通式 II 的成盐阳离子亚氨基脲衍生物 其中R5、R5、R6、R6和R7独立地为H、NH2、 本发明还提供了制备上述N-膦酰甲基甘氨酸亚氨基脲盐以及提供含有上述N-膦酰甲基甘氨酸亚氨基脲盐的植物毒性组合物的工艺。
• o-Iodoxybenzoic acid mediated oxidative condensation: synthesis of guanidines using 1,-3-disubstituted thiourea precursors
  作者：Prasad S. Dangate、Krishnacharya G. Akamanchi

  DOI：10.1016/j.tetlet.2012.09.130

  日期：2012.12

  An efficient and mild oxidative condensation procedure using o-iodoxybenzoic acid and triethylamine or ammonia as base has been developed for the synthesis of guanidines starting from easily synthesizable 1,3-disubstituted thioureas and amines or ammonia. (C) 2012 Elsevier Ltd. All rights reserved.
• An expedient synthesis of substituted guanidines
  作者：Krishnamurthy Ramadas、Natarajan Srinivasan

  DOI：10.1016/0040-4039(95)00360-o

  日期：1995.4

  This work discusses a rapid synthesis of substituted guanidines from 1,3-disubstituted thloureas using copper sulphate-silica gel in the presence of an amine. The method surpasses the previous known methods for the synthesis.
• Process of preparing substituted guanidines
  申请人：IG FARBENINDUSTRIE AG

  公开号：US01953494A1

  公开（公告）日：1934-04-03