2-methoxy-3,3-dimethyl-2-phenyl-oxirane | 13694-96-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-methoxy-3,3-dimethyl-2-phenyl-oxirane
• 英文别名: 1-Methoxy-1-phenyl-2-methyl-1,2-epoxypropan；2-methoxy-2-phenyl-3,3-dimethyloxirane；2-Methoxy-3,3-dimethyl-2-phenyloxiran；Oxirane, 2-methoxy-3,3-dimethyl-2-phenyl-；2-methoxy-3,3-dimethyl-2-phenyloxirane
• CAS: 13694-96-7
• 化学式: C₁₁H₁₄O₂
• 分子量: 178.231
• InChiKey: VRWKKNHCINTJMN-UHFFFAOYSA-N

物化性质

• 沸点：
  85-85.5 °C(Press: 9.5 Torr)
• 密度：
  1.012 g/cm3(Temp: 17 °C)

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  21.8
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-methoxy-3,3-dimethyl-2-phenyl-oxirane 在 copper(l) iodide 、 叔丁醇 作用下， 以 甲苯 为溶剂， 反应 16.0h， 以85%的产率得到2-羟基-2-甲基-1-苯基-1-丙酮
  参考文献：
  名称：

  铜催化的N-甲苯磺酰hydr生成α-烷氧基环烯酮

  摘要：

  20 mol％的碘化亚铜和叔丁醇锂的组合会触发从很容易获得的N-甲苯磺酰azo生成大量取代的，官能化的α-烷氧基2 H-萘烯酮。数据表明，这种转变是通过类铜环铜与酯的环加成反应发生的，然后是路易斯酸催化的原位生成的烷氧基环氧中间体的[1,2]烷基转移。

  DOI：

  10.1002/anie.201505993
• 作为产物：
  描述：

  2,2-dimethyl-5-methoxy-5-phenyl-1,3,4-Δ³-oxadiazoline 以 苯 为溶剂， 反应 5.0h， 以90%的产率得到2-methoxy-3,3-dimethyl-2-phenyl-oxirane
  参考文献：
  名称：

  Electrooxidative cyclization of N-acylhydrazones of aldehydes and ketones to .DELTA.3-1,3,4-oxadiazolines and 1,3,4-oxadiazoles

  摘要：

  The electrolytic oxidation of ketone N-acylhydrazones (1) in methanolic sodium acetate induced their intramolecular cyclization to the corresponding 2-methoxy-DELTA(3)-1,3,4-oxadiazolines 3. The thermal stability of a given oxadiazoline and what products were formed by its thermal decomposition was found to depend on the natures of the substituents at C-2. Thus, 2-methoxy-2-phenyloxadiazolines preferentially yielded oxiranes 5, whereas 2-alkyl-2-methoxyoxadiazolines preferentially gave enol ethers 6. 2,2-Dimethoxyoxadiazolines decomposed to the parent ketones and many unidentified products. The electrolytic oxidation of aldehyde N-acylhydrazones 2 gave 2,5-disubstituted 1,3,4-oxadiazoles 4. The oxidative cyclization of the N-benzoylhydrazones of aliphatic aldehydes gave especially high yields of the corresponding heterocycles.

  DOI：

  10.1021/jo00031a014

文献信息

• [EN] METAL FREE BLEACHING COMPOSITION<br/>[FR] COMPOSITION DE BLANCHIMENT DÉPOURVUE DE MÉTAL
  申请人：BASF SE

  公开号：WO2012000846A1

  公开（公告）日：2012-01-05

  The present invention relates to the use of a composition comprising specific a-amino- ketones, H2O2, a H2O2 precursor or a peracid and optionally an activator as a bleaching mixture for textile materials or dishes either manually or in an automatic washing machine or dish washer. Further aspects of the invention are the composition comprising specific a- aminoketones and H2O2, a H2O2 precursor or a peracid and a process for bleaching of stains or of soiling on textile materials or dishes in the context of a washing process either manually or in an automatic washing machine or dish washer. Also aspects of the invention are detergent formulations comprising such a composition and novel compounds.

  本发明涉及使用包含特定α-氨基酮、H2O2、H2O2前体或过氧酸以及可选的活化剂作为漂白混合物，用于手工或自动洗衣机或洗碗机中的纺织材料或餐具的漂白。该发明的其他方面包括包含特定α-氨基酮和H2O2、H2O2前体或过氧酸的组合物，以及用于手工或自动洗衣机或洗碗机中的洗涤过程中漂白纺织材料或餐具上的污渍或污垢的方法。此外，该发明的方面还包括包含这种组合物和新化合物的洗涤剂配方。
• Formation of Bis(2-oxazolidinone) Derivatives by Reactions of 2-Methoxy-3,3-dimethyl-2-phenyloxirane or α-Bromoisobutyrophenone with Carbon Dioxide and Aliphatic α,ω-Diamines
  作者：Norio Saito、Kiyotaka Hatakeda、Shota Ito、Takashi Asano、Takashi Toda

  DOI：10.1246/bcsj.59.1629

  日期：1986.5

  afforded corresponding 3-(ω-aminoalkyl)-4-hydroxy-5,5-dimethyl-4-phenyl-2-oxazolidinones and 3,3′-polymethylenebis[4-hydroxy-5,5-dimethyl-4-phenyl-2-oxazolidinones] derivatives, while ethylenediamine gave only mono(2-oxazolidinone) derivative.

  研究了 2-甲氧基-3,3-二甲基-2-苯基环氧乙烷或 α-溴代异丁酰苯与二氧化碳在脂肪族 α,ω-二胺存在下的反应。1,4-丁二胺、1,6-己二胺、1,8-辛二胺和1,4-双(氨基甲基)苯得到相应的3-(ω-氨基烷基)-4-羟基-5,5-二甲基-4-苯基-2-恶唑烷酮和 3,3'-聚亚甲基双[4-羟基-5,5-二甲基-4-苯基-2-恶唑烷酮]衍生物，而乙二胺仅产生单（2-恶唑烷酮）衍生物。
• METAL FREE BLEACHING COMPOSITION
  申请人：Frey Markus

  公开号：US20130117941A1

  公开（公告）日：2013-05-16

  The present invention relates to the use of a composition comprising specific a-amino-ketones, H 2 O 2 , a H 2 O 2 precursor or a peracid and optionally an activator as a bleaching mixture for textile materials or dishes either manually or in an automatic washing machine or dish washer. Further aspects of the invention are the composition comprising specific a-aminoketones and H 2 O 2 , a H 2 O 2 precursor or a peracid and a process for bleaching of stains or of soiling on textile materials or dishes in the context of a washing process either manually or in an automatic washing machine or dish washer. Also aspects of the invention are detergent formulations comprising such a composition and novel compounds.

  本发明涉及使用一种包含特定α-氨基酮、H2O2、H2O2前体或过氧酸和可选激活剂的组合物作为漂白混合物，用于手动或自动洗衣机或洗碗机中的纺织材料或餐具。本发明的进一步方面是包含特定α-氨基酮和H2O2、H2O2前体或过氧酸的组合物的漂白过程，用于手动或自动洗衣机或洗碗机中的纺织材料或餐具上的污渍或污垢。此外，本发明的方面还包括包含这种组合物的洗涤剂配方和新化合物。
• Welle, Frank; Verevkin, Sergej P.; Keller, Manfred, Chemische Berichte, 1994, vol. 127, # 4, p. 697 - 710
  作者：Welle, Frank、Verevkin, Sergej P.、Keller, Manfred、Beckhaus, Hans-Dieter、Ruechardt, Christoph

  DOI：——

  日期：——
• Samochwalow et al., Zhurnal Obshchei Khimii, 1957, vol. 27, p. 2501,2505; engl. Ausg. S. 2560, 2563
  作者：Samochwalow et al.

  DOI：——

  日期：——