3-Methyl-2-phenyl-pentanol-3 | 33484-95-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-Methyl-2-phenyl-pentanol-3
• 英文别名: 3-Methyl-2-phenylpentan-3-ol
• CAS: 33484-95-6
• 化学式: C₁₂H₁₈O
• 分子量: 178.274
• InChiKey: QYQFZJTUEHHHQO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  3-Methyl-2-phenyl-pentanol-3 在 氯化亚砜 作用下， 生成 3-Chlor-3-methyl-2-phenyl-pentan
  参考文献：
  名称：

  Gelin,R.; Chantegrel,B., Bulletin de la Societe Chimique de France, 1971, p. 2527 - 2544

  摘要：

  DOI：
• 作为产物：
  描述：

  ethyl magnesium iodide 、 3-苯基-2-丁酮 以 乙醚 为溶剂， 生成 3-Methyl-2-phenyl-pentanol-3
  参考文献：
  名称：

  Gelin,R.; Chantegrel,B., Bulletin de la Societe Chimique de France, 1971, p. 2527 - 2544

  摘要：

  DOI：

文献信息

• Reactivity of the secondary benzylic Grignard reagent from 1-phenylethyl chloride with aldehydes and ketones. More evidence for the rearrangement mechanism in benzyl Grignard reactions
  作者：Claude Bernardon

  DOI：10.1016/0022-328x(89)87200-6

  日期：1989.5

  the reaction of the Grignard reagent from benzyl chloride with aldehydes has been obtained from a study of the interaction of the Grignard reagent from 1-phenylethyl chloride with carbonyl compounds. This Grignard reagent reacts with ketones (except non-enolisable ketones) to give normal alcohols in low yields, and with aldehydes to give diols. However, in contrast to that formed in the reaction of

  通过对1-苯乙基氯与羰基化合物的格氏试剂的相互作用的研究，获得了先前提出的用于解释格利雅试剂从苄基氯与醛反应中二醇形成的机理的其他证据。这种格氏试剂与酮（不可烯醇化的酮除外）反应以低产率得到正构醇，并与醛反应得到二醇。但是，与氯化苄基镁反应中形成的相反，在某些情况下可以分离出由相应醇盐的重排形成的不稳定的三烯醇，并将其作为主要产物，从而提供了确证的证据，表明该反应中存在最初的可逆重排。的格氏试剂与羰基化合物的反应
• Compositions comprising encapsulated material
  申请人：Ness Nicholas Jeremy

  公开号：US20060039934A1

  公开（公告）日：2006-02-23

  A composition such as a water-based consumer product comprises material (e.g. perfume) encapsulated within shell capsules, each capsule comprising an encapsulating wall having an inner surface and an outer surface, with a coating on the inner surface and/or outer surface of the shell wall, the composition further comprising surfactant and/or solvent. The coating can improve the barrier properties of the shell and can enhance retention of the encapsulated materials within the shell.

  一种水基消费品的组合物，包括封装在壳体胶囊内的材料（例如香水），每个胶囊包括具有内表面和外表面的封装壁，壳体壁的内表面和/或外表面上有涂层，组合物进一步包括表面活性剂和/或溶剂。涂层可以改善壳体的屏障性能，并可以增强封装材料在壳体内的保留能力。
• EXTERNAL DERMAL COMPOSITION FOR ANTI-AGEING AND METHOD FOR PRODUCING THE SAME
  申请人：HAYASHIBARA CO., LTD.

  公开号：US20150342854A1

  公开（公告）日：2015-12-03

  The present invention has an object to provide an external dermal composition for anti-ageing, which prevents or improves apparent skin problems such as wrinkles, fine wrinkles, blemishes, and saggings caused by increasing age or ageing; and maintains or improves the barrier function and the hyaluronic acid production in the skin. The object is solved by providing an external dermal composition for anti-ageing, which contains an aqueous medium as a base material and one or more ingredients selected from L-ascorbic acid, derivatives thereof, and their salts as an effective ingredient(s).

  本发明的目的是提供一种用于抗衰老的外用皮肤组成物，该组成物可以预防或改善因年龄增长或衰老引起的皮肤问题，如皱纹、细纹、斑点和下垂，并维持或改善皮肤的屏障功能和透明质酸的产生。本发明通过提供一种外用皮肤组成物来实现该目的，该组成物包含水性介质作为基材料，并含有一种或多种从L-抗坏血酸、其衍生物和它们的盐中选择的成分作为有效成分。
• Fragranced compositions comprising encapsulated material
  申请人：QUEST INTERNATIONAL B.V.

  公开号：EP1393706A1

  公开（公告）日：2004-03-03

  A fragranced composition such as a water-based consumer product comprises material (e.g. perfume) encapsulated within shell capsules, each capsule comprising an encapsulating wall having an inner surface and an outer surface, with a coating on the inner surface and/or outer surface of the shell wall, the composition further comprising surfactant and/or solvent. The coating can improve the barrier properties of the shell and can enhance retention of the encapsulated materials within the shell.

  一种香味组合物，如水基消费品，包括封装在外壳胶囊中的材料（如香水），每个胶囊包括一个具有内表面和外表面的封装壁，外壳壁的内表面和/或外表面有一层涂层，组合物还包括表面活性剂和/或溶剂。涂层可以提高外壳的阻隔性能，并能增强封装材料在外壳内的保留。
• External dermal composition for anti-ageing and method for producing the same
  申请人：Hayashibara Co., Ltd.

  公开号：US10111822B2

  公开（公告）日：2018-10-30

  The present invention has an object to provide an external dermal composition for anti-ageing, which prevents or improves apparent skin problems such as wrinkles, fine wrinkles, blemishes, and saggings caused by increasing age or ageing; and maintains or improves the barrier function and the hyaluronic acid production in the skin. The object is solved by providing an external dermal composition for anti-ageing, which contains an aqueous medium as a base material and one or more ingredients selected from L-ascorbic acid, derivatives thereof, and their salts as an effective ingredient(s).

  本发明的目的是提供一种用于抗衰老的外用真皮组合物，该组合物可预防或改善因年龄增长或老化引起的皱纹、细小皱纹、斑点和疤痕等明显的皮肤问题，并保持或改善皮肤的屏障功能和透明质酸的生成。本发明的目的是提供一种用于抗衰老的外用皮肤组合物，该组合物含有作为基质材料的水介质和作为有效成分的一种或多种选自 L-抗坏血酸、其衍生物及其盐类的成分。