cis-1-Phenylhydrazono-propan | 5311-88-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: cis-1-Phenylhydrazono-propan
• 英文别名: syn-Propionaldehyd-phenylhydrazon；propionaldehyde phenylhydrazone；Einecs 226-168-7；N-[(E)-propylideneamino]aniline
• CAS: 5311-88-6
• 化学式: C₉H₁₂N₂
• 分子量: 148.208
• InChiKey: DRURZGNJHCCKHQ-CSKARUKUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  24.4
• 氢给体数：
  1
• 氢受体数：
  2

安全信息

• 海关编码：
  2928000090

反应信息

• 作为反应物：
  描述：

  cis-1-Phenylhydrazono-propan 生成 苯胺
  参考文献：
  名称：

  KUZNETSOV, M. A.;SUVOROV, A. A., ZH. ORGAN. XIMII, 1982, 18, N 9, 1923-1931

  摘要：

  DOI：
• 作为产物：
  描述：

  (phenylazo)-n-propane 生成 cis-1-Phenylhydrazono-propan
  参考文献：
  名称：

  KUZNETSOV, M. A.;SUVOROV, A. A., ZH. ORGAN. XIMII, 1982, 18, N 9, 1923-1931

  摘要：

  DOI：

文献信息

• Alkanoyl chloride phenylhydrazones
  申请人：The Upjohn Company

  公开号：US04094906A1

  公开（公告）日：1978-06-13

  Certain alkanoyl chloride phenylhydrazones have been found to be active against insects and mites, and also active as herbicides. The phenylhydrazone ring can be substituted. Suitable substituent groups are halogen atoms, the nitro group, the trifluoromethyl group, and alkyl groups of from 1 to 6 carbon atoms, inclusive. The compounds are prepared by reacting an alkanoic acid phenylhy-drazide with phosphorus pentachloride to obtain an alkanoyl chloride (dichlorophosphinyl)phenylhydrazone intermediate that is reacted with phenol to produce the desired alkanoyl chloride phenylhydrazone. Certain compounds can be prepared by direct chlorination of an alkanaldehyde phenylhydrazone. Some of the compounds are novel. Methods of use and compositions are described.

  某些酰氯苯基肼已被发现对昆虫和螨类具有活性，并且作为除草剂也具有活性。苯基肼环可被取代。适当的取代基包括卤素原子、硝基、三氟甲基和含有1至6个碳原子的烷基。这些化合物是通过将烷酸苯基肼与五氯化磷反应制备而成的，以获得一种烷酰氯（二氯磷酰）苯基肼中间体，然后将其与酚反应以产生所需的烷酰氯苯基肼。某些化合物可以通过直接氯化烷醛苯基肼来制备。其中一些化合物是新颖的。描述了使用方法和组合物。
• METHODS FOR THE PREPARATION OF PYRAZOLE-CONTAINING COMPOUNDS
  申请人：Deng Xiaohu

  公开号：US20070260057A1

  公开（公告）日：2007-11-08

  The present invention is directed to novel processes for the preparation of fused pyrazole compounds, useful for the treatment of disorders and conditions mediated by serotonin receptor activity.

  本发明涉及一种用于制备融合吡唑化合物的新型方法，该化合物对通过5-羟色胺受体活性介导的疾病和症状的治疗具有用处。
• Michael additions of hydrazones for carbon–carbon bond formation
  作者：Jack E. Baldwin、Robert M. Adlington、Jeffrey C. Bottaro、Ashok U. Jain、Jayant N. Kolhe、Matthew W. D. Perry、Ian M. Newington

  DOI：10.1039/c39840001095

  日期：——

  The lithium salts of t-butyl-and trityl-hydrazones react with methyl crotonate to form C-trapped azo-esters and similar products were observed from a thermal ene-reaction of aldehyde t-butylhydrazones with methyl acrylate or acrylonitrile, and aldehyde phenylhydrazones with methyl acrylate; these products can be diverted into synthetically useful γ-keto-esters, γ-keto-nitriles, saturated esters, γ

  叔丁基hydr和三苯甲基-的锂盐与巴豆酸甲酯反应形成C捕获的偶氮酯，并且通过醛叔丁基hydr与丙烯酸甲酯或丙烯腈的热烯反应，以及醛苯hydr与丙烯的热烯反应观察到类似的产物。丙烯酸甲酯 这些产品可以分为合成有用的γ-酮酯，γ-酮腈，饱和酯，γ-烷基-2-吡咯烷酮和γ-氨基酯。
• Facile synthesis of hydrazonyl halides by reaction of hydrazones with N-halosuccinimide-dimethyl sulfide complex
  作者：Himatkumar V. Patel、Kavita A. Vyas、Sudhanshu P. Pandey、Peter S. Fernandes

  DOI：10.1016/0040-4020(95)00916-7

  日期：1996.1

  new and convenient method is described for the synthesis of hydrazonyl halides. Hydrazones on treatment with N-chlorosuccinimide-dimethyl sulfide complex result in the formation of the corresponding hydrazonyl chlorides in good yields. Similarly, treatment of hydrazones with N-bromosuccinimide-dimethyl sulfide complex gives the corresponding hydrazonyl bromide under extremely mild conditions.

  描述了一种新的方便的合成肼基卤化物的方法。用N-氯代琥珀酰亚胺-二甲基硫醚络合物处理的导致以良好的产率形成相应的酰肼酰氯。类似地，用N-溴代琥珀酰亚胺-二甲基硫醚络合物处理hydr，可在极其温和的条件下得到相应的酰溴。
• Optodynamers: expression of color and fluorescence at the interface between two films of different dynamic polymers
  作者：Takashi Ono、Shunsuke Fujii、Tadahito Nobori、Jean-Marie Lehn

  DOI：10.1039/b712454f

  日期：——

  Color and fluorescence changes were expressed at the interface between two different polyhydrazone polymer films, induced by hydrazone bond exchange and component recombination through the interface, resulting in an extension of conjugation.

  两种不同的聚腙聚合物薄膜之间的界面处表现出颜色和荧光的变化，这是由腙键交换和通过界面的组分重组引起的，导致共轭的延伸。