2,2'-偶氮二(2-脒基丙烷) | 13217-66-8

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 2,2'-偶氮二(2-脒基丙烷)
• 英文名称: AAPH (2,2′-azobis-(amidinopropane)dihydrochloride)
• 英文别名: 2,2’-Azobis-(2-amidinopropane)-dihydrochloride；2,2’-azobis (2-amidinopropane) dihydrochloride；2,2′-azobios(2-amidinopropane)dihydrocloride；2,2-Azobis(2-methylpropionamidine) dihydrochloride；2,2'-azobis(2-amidinopropane)dihydrochloride；2,2′-Azobis(2-methylpropionamidine)；2,2'-Azobis(2-amidinopropane)；2-[(1-amino-1-imino-2-methylpropan-2-yl)diazenyl]-2-methylpropanimidamide
• CAS: 13217-66-8
• 化学式: C₈H₁₈N₆
• mdl: MFCD20542840
• 分子量: 198.271
• InChiKey: CCTFAOUOYLVUFG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.2
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  125
• 氢给体数：
  4
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  dimethylaminopropylacrylamide 、 氯甲烷 、 丙烯酰胺 、 2,2'-偶氮二(2-脒基丙烷) 、 、 水 在 氮气 、 水 作用下， 反应 0.5h， 生成 4-(二甲氨基)苯乙酸
  参考文献：
  名称：

  Water soluble powdered cationic polyelectrolyte comprising a copolymer

  摘要：

  一种水溶性的粉末阳离子聚电解质，包括丙烯酰胺和二甲基氨丙基丙烯酰胺的共聚物，其中a) 二甲基氨丙基丙烯酰胺被矿物酸中和；b) 共聚物的内禀粘度与丙烯酰胺与二甲基氨丙基丙烯酰胺的摩尔比之商大于200；c) 聚合物中阳离子单体的比例在4至80摩尔％之间，该共聚物是通过基本无双官能团化合物的丙烯酰胺和二甲基氨丙基丙烯酰胺的共聚得到的。

  公开号：

  US05512646A1
• 作为产物：
  描述：

  偶氮二异丁腈 在 盐酸 、 甲醇 作用下， 生成 2,2'-偶氮二(2-脒基丙烷)
  参考文献：
  名称：

  Haines; Waters, Journal of the Chemical Society, 1958, p. 3221

  摘要：

  DOI：
• 作为试剂：
  描述：

  (Z,Z)-9,12-十八烷二烯酸二聚物 在 phosphate buffer 、 2,2'-偶氮二(2-脒基丙烷) 、 sodium dodecyl-sulfate 、 天然维生素E 作用下， 以 乙醇 、 水 为溶剂， 生成 alkaline earth salt of/the/ methylsulfuric acid
  参考文献：
  名称：

  A rapid screening test to determine the antioxidant potencies of natural and synthetic antioxidants

  摘要：

  This paper presents a simple and convenient method for measuring antioxidant efficiencies in a model system consisting of micelles of sodium dodecyl sulfate (SDS) with added linoleic acid. The analytical method involves following the development of absorption at 234 nm due to the conjugated diene hydroperoxide of linoleic acid; 2,2'-azobis(2-amidinopropane) dihydrochloride (ABAP) is used as the initiator. The antioxidant efficiency of an antioxidant is defined as AE = k(inh)/k(p), where k(inh) is the rate constant for reaction of the peroxyl radical from linoleic acid with the antioxidant (eq 7 in the text) and k(p) is the propagation rate constant for autoxidation of linoleic acid (eq 5). The relative antioxidant efficiency (RAE) is defined as the AE of the test compound divided by that for alpha-tocopherol; thus, RAE values are equal to k(inh)/k(inh,alpha-tocopherol). Since the absolute value of the rate constant for reaction of alpha-tocopherol with peroxyl radicals is known in micellar systems, the absolute value of k(inh) for a given antioxidant can be calculated if required. To establish the reliability of the method we report the AE of 17 synthetic and naturally occurring antioxidants and compare values obtained by this method to others in the literature. For neutral antioxidants, the same AE values are obtained in both negatively-charged micelles of SDS and positively-charged micelles of hexadecyl trimethylammonium bromide (HDTBr). The relative antioxidant efficiencies are reported for more than 40 synthetic compounds that are potential antioxidants or anti-inflammatory compounds; most of these compounds are tocopherol, ascorbate, or 2-hydroxytetronic acid analogues. Although the charge type of the micelle has no effect on the RAE of neutral antioxidants, micelles of different charge types do have an effect on the RAE value of charged antioxidants such as ascorbic acid, other 2-hydroxytetronic acids, and Trolox C. In 0.10 M SDS micelles, ascorbic acid and alpha-tocopherol are shown to have an additive effect, not a synergistic effect, as antioxidants.

  DOI：

  10.1021/jo00065a013

文献信息

• Water soluble, powdered, cationic polyelectrolyte comprising a copolymer of acrylamide and dimethylaminopropylacrylamide essentially free of bifunctional compounds
  申请人：Chemische Fabrik Stockhausen GmbH

  公开号：US06228964B1

  公开（公告）日：2001-05-08

  A water-soluble, powdered, cationic polyelectrolyte comprising a copolymer of acrylamide and dimethylaminopropylacrylamide which is essentially free of bifunctional compounds and in which a) the dimethylaminopropylacrylamide is quaternized; b) the quotient of the intrinsic viscosity of the copolymers divided by the molar ratio of acrylamide to dimethylaminopropylacrylamide is greater than 200; and c) the proportion of the cationic monomers in the polymer is between 4 and 80 mol-%, the copolymer having been obtained by copolymerization of acrylamide and quaternized dimethylaminopropylacrylamide said quaternized dimethylaminopropylacrylamide having been obtained by the reaction of dimethylaminopropylacrylamide with a quaternizing agent in the absence of acrylamide.

  一种水溶性的粉末阳离子聚电解质，包括丙烯酰胺和二甲基氨丙基丙烯酰胺共聚物，基本上不含双官能团化合物，其中a）二甲基氨丙基丙烯酰胺是季铵化的；b）共聚物的内禀粘度与丙烯酰胺与二甲基氨丙基丙烯酰胺的摩尔比之商大于200；c）聚合物中阳离子单体的比例在4至80摩尔％之间，该共聚物是由丙烯酰胺和季铵化的二甲基氨丙基丙烯酰胺共聚而成，所述季铵化的二甲基氨丙基丙烯酰胺是在丙烯酰胺不存在的情况下与季铵化剂反应得到的。
• Aliphatic azo compounds having guanyl radicals on tertiary carbon attached to azo nitrogen
  申请人：DU PONT

  公开号：US02599299A1

  公开（公告）日：1952-06-03
• Haines; Waters, Journal of the Chemical Society, 1958, p. 3221
  作者：Haines、Waters

  DOI：——

  日期：——
• Water soluble powdered cationic polyelectrolyte comprising a copolymer
  申请人：Chemische Fabrik Stockhausen GmbH

  公开号：US05512646A1

  公开（公告）日：1996-04-30

  A water-soluble, powdered, cationic polyelectrolyte comprising a copolymer of acrylamide and dimethylaminopropylacrylamide in which a) the dimethylaminopropylacrylamide is neutralized with mineral acids; b) the quotient of the intrinsic viscosity of the copolymers divided by the molar ratio of acrylamide to dimethylaminopropylacrylamide is greater than 200; and c) the proportion of the cationic monomers in the polymer is between 4 and 80 mol-%, the copolymer having been obtained by copolymerization of acrylamide and dimethylaminopropylacrylamide that is essentially free of bifunctional compounds.

  一种水溶性的粉末阳离子聚电解质，包括丙烯酰胺和二甲基氨丙基丙烯酰胺的共聚物，其中a) 二甲基氨丙基丙烯酰胺被矿物酸中和；b) 共聚物的内禀粘度与丙烯酰胺与二甲基氨丙基丙烯酰胺的摩尔比之商大于200；c) 聚合物中阳离子单体的比例在4至80摩尔％之间，该共聚物是通过基本无双官能团化合物的丙烯酰胺和二甲基氨丙基丙烯酰胺的共聚得到的。