5-isopentyl-2-methoxybenzaldehyde

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 5-isopentyl-2-methoxybenzaldehyde
• 英文别名: 2-Methoxy-5-(3-methylbutyl)benzaldehyde
• 化学式: C₁₃H₁₈O₂
• 分子量: 206.285
• InChiKey: FXLGCNLTKNOTRY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  15
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  5-isopentyl-2-methoxybenzaldehyde 在 三溴化硼 作用下， 以 二氯甲烷 为溶剂， 生成 2-hydroxy-5-isopentyl-benzaldehyde
  参考文献：
  名称：

  Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same

  摘要：

  公开号：

  EP0512570B1
• 作为产物：
  描述：

  二氯(二氯甲氧基)甲烷 、 1-isopentyl-4-methoxybenzene 、 四氯化锡 以 二氯甲烷 为溶剂， 生成 5-isopentyl-2-methoxybenzaldehyde
  参考文献：
  名称：

  Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same

  摘要：

  公开号：

  EP0512570B1

文献信息

• Glucose-6-Phosphate Dehydrogenase (G6PD)-Modulating Agents And Methods Of Treating G6PD Deficiency
  申请人：The Board of Trustees of the Leland Stanford Junior University

  公开号：US20200223826A1

  公开（公告）日：2020-07-16

  Aspects of the present disclosure include G6PD-modulating agents and methods for modulating a glucose-6-phosphate dehydrogenase (G6PD) in a sample using such agents. A G6PD-modulating agent can be dimeric and include two terminal carbocyclic or heterocyclic groups connected via a linker. In some instances, the agent includes a diamino-containing linker. In certain cases, the agent includes two amino substituents. Also provided are methods for treating a subject for a G6PD deficiency-associated condition, that include administering to a subject an effective amount of a G6PD-modulating agent to selectively activate a mutant G6PD and treat the subject. Kits and compositions for practicing the subject methods are also provided.
• Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same
  申请人：FUJISAWA PHARMACEUTICAL CO., LTD.

  公开号：EP0512570B1

  公开（公告）日：1995-10-11