[Ru(bpy)(dppz)Cl₂] | 1603162-58-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 菲咯啉
• 英文名称: [Ru(bpy)(dppz)Cl₂]
• 英文别名: cis-[Ru(bpy)(dppz)Cl₂]；dichlororuthenium;2-pyridin-2-ylpyridine;quinoxalino[2,3-f][1,10]phenanthroline
• CAS: 1603162-58-8
• 化学式: C₂₈H₁₈Cl₂N₆Ru
• 分子量: 610.467
• InChiKey: SKFYZUDDOBTTET-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  7.4
• 重原子数：
  37
• 可旋转键数：
  0
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  77.3
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  [Ru(bpy)(dppz)Cl₂] 、 sodium sulfite 在 sodium nitrite 作用下， 以 乙醇 、 水 为溶剂， 以70 %的产率得到cis-Na[Ru(bpy)(dppz)(SO3)(NO2)]
  参考文献：
  名称：

  10.1039/d4dt01033g

  摘要：

  DOI：

  10.1039/d4dt01033g
• 作为产物：
  描述：

  1,10-phenanthroline-5,6-quinone 以 乙醇 、 丙酮 为溶剂， 反应 15.08h， 生成 [Ru(bpy)(dppz)Cl₂]
  参考文献：
  名称：

  Structural and optical properties of new cyclometalated Ru(II) derived compounds

  摘要：

  The electronic spectra of 4 cyclometalated ruthenium compounds built up from cycloruthenated 2-phenylpyridine with monodentate and bidentate ligands, namely (1) under bar1 [Ru(MeCN)(2)(phen)(PhPy)](1+) (RDC11), (2) under bar [Ru(phen)(2)(PhPy)](1+) (RDC34), (3) under bar [Ru(MeCN)(2)(PhPy)(dppz)](1+) (RDC11Z), (4) under bar [Ru(bpy) (PhPy)(dppz)](1+) (RDCbpZ), the last two being newly synthesized, have been recorded and calculated together with that of (5) under bar [Ru(bpy)(2)(dppz)](2+) (RDNbpZ). Recently synthesized variants of RDC34 where the phenylpyridine ligand is substituted with an electro-attractor or an electro-donor group, (6) under bar [Ru(phen)(2)(NO2PhPy)](1+) RDC40 and (7) under bar [Ru(phen)(2)(NH2PhPy)](1+) RDC41 respectively, and the dicationic reference complex [Ru (phen)(2)(bpy)](2+) (RDN34) have been investigated as well for comparison. The global structures of RDC34 and RDN34 are very similar despite of the substitution of one N atom by one C atom. As expected a shortening of the Ru-C bond as compared to the Ru-N bond is observed. The calculated structures of the investigated complexes point to a rather rigid structure whatever their environment. The introduction of a strong Ru-C bond has a minor effect on the coordination sphere around the metal atom keeping the other Ru-N bonds and bond angles similar, the only noticeable alteration being an increase of the Ru-N bond trans to the Ru-C bond. The experimental spectra are characterized by an intense band in the UV domain centered at 270 nm and corresponding to a strong intra-ligand (IL) absorption. Low-lying MLCT states contribute to a weak shoulder around 370 nm and to a large band between 550 nm and 400 nm. The tail of this band, towards 650 nm, is a characteristic of the cyclometalated complexes. This series of molecules, as other polypyridyl complexes, are characterized by a high density of excited states in the vis/UV energy domain, a large mixing between MLCT/IL and LLCT states in the upper part of the spectrum, and a significant sensitivity to the environment of the IL state localized on the dppz ligands. (C) 2013 Published by Elsevier B.V.

  DOI：

  10.1016/j.jorganchem.2013.08.032

文献信息

• Aryl-Substituted Ruthenium(II) Complexes: A Strategy for Enhanced Photocleavage and Efficient DNA Binding
  作者：Felipe Diógenes Abreu、Tercio de F. Paulo、Marcelo H. Gehlen、Rômulo A. Ando、Luiz G. F. Lopes、Ana Cláudia S. Gondim、Mayron A. Vasconcelos、Edson H. Teixeira、Eduardo Henrique Silva Sousa、Idalina Maria Moreira de Carvalho

  DOI：10.1021/acs.inorgchem.7b01108

  日期：2017.8.7

  synthesized two new ruthenium complexes that combine an efficient DNA binding moiety (dppz ligand) together with naphthyl-modified (1) and anthracenyl-modified (2) bipyridine as a strong ROS generator bound to a ruthenium complex. The compounds were fully characterized and their photophysical and photochemical properties investigated. Compound 2 showed one of the highest quantum yields for singlet oxygen

  钌多吡啶复合物已显示出有望用作光动力疗法（PDT）的试剂和分子生物学工具（生色团辅助的光灭活）。为了完成这些任务，重要的是至少要具有目标选择性和巨大的活性氧（ROS）光生能：在同一分子中不容易发现的两个特性。为了制备这种新试剂，我们合成了两种新的钌配合物，它们结合了有效的DNA结合部分（dppz配体）与萘基修饰的（1）和蒽基修饰的（2）联吡啶作为结合到钌配合物上的强ROS产生剂。对该化合物进行了充分表征，并研究了它们的光物理和光化学性质。化合物2表明曾报道为单线态氧产生的最高量子产率中的一个（Φ Δ = 0.96），具有非常高的DNA结合沿（日志ķ b= 6.78）。这种光化学行为可归因于较低的三重态，涉及蒽基修饰的联吡啶，这与较容易的氧猝灭有关。此外，这些化合物对G-四链体DNA表现出中等选择性，并与DNA的小沟结合，这很可能是由侧基配体驱动的。有趣的是，即使暴露于黄色发光二极管（LED
• An efficient route to asymmetrically diconjugated tris(heteroleptic) complexes of Ru(<scp>ii</scp>)
  作者：Christopher S. Burke、Tia E. Keyes

  DOI：10.1039/c6ra06086b

  日期：——

  highly efficient and versatile route to the preparation of tris(heteroleptic) Ru(II) polypyridyl complexes is described which permits access to two or more independently conjugatable termini in the final structure. The strategy utilizes the well-known Ru(DMSO)4Cl2 precursor to form the Ru(N^N)(DMSO)2Cl2 product and then proceeds through an oxalate intermediate which can be cleaved under acidic conditions

  描述了一种制备三（杂）Ru（II）聚吡啶基配合物的高效且通用的途径，其允许在最终结构中进入两个或更多个独立可缀合的末端。该策略利用众所周知的Ru（DMSO）4 Cl 2前体形成Ru（N ^ N）（DMSO）2 Cl 2产物，然后通过可在酸性条件下裂解的草酸盐中间体进行控制，以控制化学计量添加聚吡啶配体与Ru（II）配位球的结合使得杂化配合物能够逐步组装。为了举例说明该方法，制备了三种配合物，包括新型化合物：[Ru（dppz）（bpyArCOOH）（bpyArCOOEt）]2+（其中dppz是二吡啶并吩嗪，bpyArCOOH和bpyArCOOEt分别是4-（4-羧基苯基）-和4-（4-乙氧基羰基苯基）-2,2-联吡啶），其中从RuCl 3原料到最终原料的合成收率产品为82％。然后描述了顺序结合-去保护-结合步骤以产生Ru（ II）复合物，该复合物既被PEG化又被肽结合。这种合成方法为扩展双配位Ru（
• Solvent- and DNA-Controlled Phototriggered Linkage Isomerization in a Ruthenium Sulfoxide Complex Incorporating Dipyrido[3,2-<i>a</i>:2′,3′-<i>c</i>]phenazine (dppz)
  作者：Daulat Phapale、Rajib Ghosh、Dipanwita Das

  DOI：10.1021/acs.inorgchem.7b00412

  日期：2017.6.5

  A new tris-heteroleptic complex [Ru(bpy)(dppz)(OSO)](ClO4), [1](ClO4) (bpy = 2,2′-bipyridine, dppz = dipyrido[3,2-a:2′,3′-c]phenazine and OSO = 2-methylsulfinylbenzoate), was synthesized and characterized to control the photochromic Ru–S → Ru–O linkage isomerization. Details isomerization kinetics studied by UV–visible absorption spectroscopy and cyclic voltammetry revealed that efficient photochromic

  一种新的三异[[ru（bpy）（dppz）（OSO）]（ClO 4），[ 1 ]（ClO 4）（bpy = 2,2'-联吡啶，dppz = dipyrido [3,2- a：合成了2'，3'- c ]吩嗪和OSO = 2-甲基亚磺酰基苯甲酸酯，并对其进行了表征，以控制光致变色Ru–S→Ru–O键的异构化。通过紫外-可见吸收光谱和循环伏安法研究的详细异构化动力学表明，有效的光致变色S→O异构化和热O→S逆转发生在碳酸亚丙酯（PC），甲醇和二氯甲烷等溶剂中。[ 1 ]（ClO 4）的光致异构化）虽然在类似化合物[Ru（bpy）2（OSO）]（ClO 4）中具有活性，但仍被阻滞在水中。通过涉及[ 1 ]（ClO 4）的dppz配体的暗3 MLCT状态，有效的激发态失活会切断水性介质中的光致变色现象。有趣的是，在存在DNA的情况下，水溶液中的光致变色被激活，该DNA通过插层屏蔽了dppz局部暗态。
• Structural and optical properties of new cyclometalated Ru(II) derived compounds
  作者：Sidonie Finck、Jean-Thomas Issenhuth、Stéphane Despax、Claude Sirlin、Michel Pfeffer、Corentin Poidevin、Christophe Gourlaouen、Alex Boeglin、Chantal Daniel

  DOI：10.1016/j.jorganchem.2013.08.032

  日期：2014.6

  The electronic spectra of 4 cyclometalated ruthenium compounds built up from cycloruthenated 2-phenylpyridine with monodentate and bidentate ligands, namely (1) under bar1 [Ru(MeCN)(2)(phen)(PhPy)](1+) (RDC11), (2) under bar [Ru(phen)(2)(PhPy)](1+) (RDC34), (3) under bar [Ru(MeCN)(2)(PhPy)(dppz)](1+) (RDC11Z), (4) under bar [Ru(bpy) (PhPy)(dppz)](1+) (RDCbpZ), the last two being newly synthesized, have been recorded and calculated together with that of (5) under bar [Ru(bpy)(2)(dppz)](2+) (RDNbpZ). Recently synthesized variants of RDC34 where the phenylpyridine ligand is substituted with an electro-attractor or an electro-donor group, (6) under bar [Ru(phen)(2)(NO2PhPy)](1+) RDC40 and (7) under bar [Ru(phen)(2)(NH2PhPy)](1+) RDC41 respectively, and the dicationic reference complex [Ru (phen)(2)(bpy)](2+) (RDN34) have been investigated as well for comparison. The global structures of RDC34 and RDN34 are very similar despite of the substitution of one N atom by one C atom. As expected a shortening of the Ru-C bond as compared to the Ru-N bond is observed. The calculated structures of the investigated complexes point to a rather rigid structure whatever their environment. The introduction of a strong Ru-C bond has a minor effect on the coordination sphere around the metal atom keeping the other Ru-N bonds and bond angles similar, the only noticeable alteration being an increase of the Ru-N bond trans to the Ru-C bond. The experimental spectra are characterized by an intense band in the UV domain centered at 270 nm and corresponding to a strong intra-ligand (IL) absorption. Low-lying MLCT states contribute to a weak shoulder around 370 nm and to a large band between 550 nm and 400 nm. The tail of this band, towards 650 nm, is a characteristic of the cyclometalated complexes. This series of molecules, as other polypyridyl complexes, are characterized by a high density of excited states in the vis/UV energy domain, a large mixing between MLCT/IL and LLCT states in the upper part of the spectrum, and a significant sensitivity to the environment of the IL state localized on the dppz ligands. (C) 2013 Published by Elsevier B.V.
• 10.1039/d4dt01033g
  作者：Martins, Patrícia H. R.、Romo, Adolfo I. B.、Gouveia Jr, Florêncio S.、Paz, Iury A.、Nascimento, Nilberto R. F.、Andrade, Alexandre L.、Rodríguez-López, Joaquín、de Vasconcelos, Mayron A.、Teixeira, Edson Holanda、Moraes, Carlos André Ferreira、Lopes, Luiz G. F.、Sousa, Eduardo Henrique Silva de

  DOI：10.1039/d4dt01033g

  日期：——