N-allyl-N'-(4-methoxy-phenyl)-thiourea | 1138-72-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-allyl-N'-(4-methoxy-phenyl)-thiourea
• 英文别名: N-Allyl-N'-(4-methoxy-phenyl)-thioharnstoff；1-(4-Methoxyphenyl)-3-(prop-2-EN-1-YL)thiourea；1-(4-methoxyphenyl)-3-prop-2-enylthiourea
• CAS: 1138-72-3
• 化学式: C₁₁H₁₄N₂OS
• mdl: MFCD00244797
• 分子量: 222.311
• InChiKey: REZDXTXPJKIOKH-UHFFFAOYSA-N

物化性质

• 熔点：
  79-81 °C
• 沸点：
  323.9±52.0 °C(Predicted)
• 密度：
  1.162±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.181
• 拓扑面积：
  65.4
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  N-allyl-N'-(4-methoxy-phenyl)-thiourea 在 basic lead(II) carbonate 、 甲苯 作用下， 生成 N-allyl-N'-(4-methoxyphenyl)carbodiimide
  参考文献：
  名称：

  Preparation of 1,2-disubstituted-3-cyanoguanidines

  摘要：

  公开号：

  US02479498A1
• 作为产物：
  描述：

  甲氧苯胺 、 天然芥菜籽油 以 氯仿 为溶剂， 生成 N-allyl-N'-(4-methoxy-phenyl)-thiourea
  参考文献：
  名称：

  通过胺，异硫氰酸盐和1,2-二氮杂-1,3-二烯的三组分顺序反应，杂环骨架多样性的有效方法

  摘要：

  通过高效的一锅三组分反应，将一组1,2-二氮杂-1,3-二烯（DDs），伯胺和异硫氰酸酯按不同的顺序添加，可以实现杂环骨架多样性实现。区分不同杂环核心形成的关键特征是N或S异源亲核试剂可用于提供第一步迈克尔加成步骤，从而提供区域选择性取代的2-硫代乙内酰脲或2-iminothiazolidinones。两个杂环的5位上的或enehydrazino侧链代表有价值的功能，可达到难以通过其他方法获得的新型5-羟基亚乙基衍生物。

  DOI：

  10.1021/jo2021949

文献信息

• Regioselective synthesis of novel 3-allyl-2-(substituted imino)-4-phenyl-3H-thiazole and 2,2′-(1,3-phenylene)bis(3-substituted-2-imino-4-phenyl-3H-thiazole) derivatives as antibacterial agents
  作者：Jafar Abbasi Shiran、Asieh Yahyazadeh、Manouchehr Mamaghani、Mehdi Rassa

  DOI：10.1016/j.molstruc.2013.02.003

  日期：2013.5

  Abstract Several novel 3-allyl-2-(substituted imino)-4-phenyl-3 H -thiazole derivatives were synthesized by the reaction of allyl-thioureas and 2-bromoacetophenone. We also report the synthesis of bis-allyl-3 H thiazoles using the reaction of various isothiocyanates and 1,3-phenylenediamine. The structures of all compounds were characterized by spectral and elemental analysis. Most of the synthesized

  摘要 通过烯丙基硫脲与2-溴苯乙酮反应合成了多种新型3-烯丙基-2-(取代亚氨基)-4-苯基-3H-噻唑衍生物。我们还报告了使用各种异硫氰酸酯和 1,3-苯二胺的反应合成双烯丙基-3 H 噻唑。所有化合物的结构均通过光谱和元素分析表征。大多数合成的化合物对沙门氏菌、藤黄微球菌、枯草芽孢杆菌和铜绿假单胞菌均表现出有效的抗菌活性。
• Non-toxic corrosion-protection pigments based on manganese
  申请人：——

  公开号：US20040011252A1

  公开（公告）日：2004-01-22

  Corrosion-inhibiting pigments based on manganese are described that contain a trivalent or tetravalent manganese/valence stabilizer complex. An inorganic or organic material is used to stabilize the trivalent or tetravalent manganese ion to form a compound that is sparingly soluble, exhibits low solubility, or is insoluble in water, depending upon the intended usage. Specific stabilizers are chosen to control the release rate of trivalent or tetravalent manganese during exposure to water and to tailor the compatibility of the powder when used as a pigment in a chosen binder system. Stabilizers may also modify the processing and handling characteristics of the formed powders. Manganese/valence stabilizer combinations are chosen based on the well-founded principles of manganese coordination chemistry. Many manganese-valence stabilizer combinations are presented that can equal the performance of conventional hexavalent chromium or tetravalent lead systems. It is emphasized that this abstract is provided to comply with the rules requiring an abstract which will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims.

  以锰为基础的缓蚀颜料含有三价或四价锰/价稳定剂复合物。一种无机或有机材料可用于稳定三价或四价锰离子，从而形成一种可少量溶解、溶解度低或不溶于水的化合物，具体取决于预期用途。选择特定的稳定剂是为了控制三价锰或四价锰在遇水时的释放率，并调整粉末在所选粘合剂体系中用作颜料时的相容性。稳定剂还可以改变成型粉末的加工和处理特性。锰/价稳定剂组合的选择是基于锰配位化学的基本原理。文中介绍了许多锰价稳定剂组合，其性能与传统的六价铬或四价铅体系相当。需要强调的是，提供本摘要是为了符合要求提供摘要的规则，以便检索者或其他读者快速确定技术公开的主题。提交本摘要的前提是，本摘要不用于解释或限制权利要求的范围或含义。
• Non-toxic corrosion-protection pigments based on rare earth elements
  申请人：——

  公开号：US20040104377A1

  公开（公告）日：2004-06-03

  A corrosion-inhibiting pigment comprising a rare earth element and a valence stabilizer combinded to form a rare earth/valence stabilizer complex. The rare earth element is selected from cerium, terbium, praseodymium, or a combination thereof, and at least one rare earth element is in the tetravalent oxidation state. An inorganic or organic material is used to stabilize the tetravalent rare earth ion to form a compound that is sparingly soluble in water. Specific stabilizers are chosen to control the release rate of tetravalent cerium, terbium, or praseodymium during exposure to water and to tailor the compatibility of the powder when used as a pigment in a chosen binder system. Stabilizers may also modify the processing and handling characteristics of the formed powders. Many rare earth-valence stabilizer combinations are presented that can equal the performance of conventional hexavalent chromium systems.

  一种缓蚀颜料，由稀土元素和价态稳定剂结合形成稀土/价态稳定剂复合物。稀土元素选自铈、铽、镨或它们的组合，至少有一种稀土元素处于四价氧化态。使用无机或有机材料来稳定四价稀土离子，以形成稀溶于水的化合物。选择特定的稳定剂是为了控制四价铈、铽或镨在遇水时的释放率，并调整粉末在所选粘合剂体系中用作颜料时的相容性。稳定剂还可以改变成型粉末的加工和处理特性。本文介绍了许多稀土-价稳定剂组合，其性能可与传统的六价铬体系媲美。
• Some Phenylthiourea Derivatives and their Antituberculous Activity
  作者：L. Doub、L. M. Richardson、D. R. Herbst、M. L. Black、O. L. Stevenson、L. L. Bambas、G. P. Youmans、A. S. Youmans

  DOI：10.1021/ja01542a043

  日期：1958.5
• Oeriu et al, Academia Republicii Populare Romine, Baza de Cercetari Stiintifice, Timisoara, Studii si Cercetari, Stiinte Chimice, 1958, vol. 6, p. 155,156
  作者：Oeriu et al

  DOI：——

  日期：——