[Cu([2-(2,3-dimethylphenyl)amino]benzoate)₂] | 55940-11-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [Cu([2-(2,3-dimethylphenyl)amino]benzoate)₂]
• 英文别名: [Cu(mefenamate)₂]；[Cu(Mef)₂]；copper(II) mephenaminate
• CAS: 55940-11-9
• 化学式: C₃₀H₂₈CuN₂O₄
• 分子量: 544.109
• InChiKey: JOIGVPQDPPCISJ-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  扑湿痛 在 potassium hydroxide 作用下， 以 乙醇 为溶剂， 反应 7.0h， 生成 [Cu([2-(2,3-dimethylphenyl)amino]benzoate)₂]
  参考文献：
  名称：

  Synthesis, characterization, and biological activity of transition metals complexes with mefenamic acid (NSAIDs)

  摘要：

  A new series of transition metal complexes have been synthesized with [(2,3-dimethylphenyl)-amino]benzoic acid (Mefenamic acid) in 1 : 1/1 : 2 M : L ratio. The complexes have been characterized by elemental analysis, FT-IR and UV-Vis spectroscopy. Antifungal, antibacterial, antitumor, antioxidant (DPPH, H2O2 induced DNA damage) activity of the complexes and DNA interaction with the complexes were studied. The results revealed that the ligand and most of synthesized compounds did not demonstrate significant antibacterial activity unlike [Ni(Mef)(H2O)Cl] that exhibited pronounced activity against F. Solani. Antitumor activity of the products was higher than that of the free ligand.

  DOI：

  10.1134/s1070363215070282

文献信息

• Grigor'eva, A. S.; Zelentsov, V. V.; Kriss, E. E., Russian Journal of Inorganic Chemistry, 1978, vol. 23, p. 1493 - 1495
  作者：Grigor'eva, A. S.、Zelentsov, V. V.、Kriss, E. E.、Stroesku, A. K.

  DOI：——

  日期：——