Phenylchlorophosphonic Acid Phenyl Ester | 61274-57-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Phenylchlorophosphonic Acid Phenyl Ester
• 英文别名: Phenylphosphonsaeurephenylesterchlorid；phenylphosphonsaurephenylesterchlorid；O-phenyl phenylphosphonochloridate；phenyl chloro(phenyl)phosphonate；phenyl phenylphosphonochloridate；diphenylphosphinic chloride；Phenyl-P-phenylphosphonochloridate；[chloro(phenyl)phosphoryl]oxybenzene
• CAS: 61274-57-5
• 化学式: C₁₂H₁₀ClO₂P
• 分子量: 252.637
• InChiKey: QEJXQVSIYPMBQC-UHFFFAOYSA-N

物化性质

• 沸点：
  152-155 °C(Press: 0.3 Torr)
• 密度：
  1.30±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  Phenylchlorophosphonic Acid Phenyl Ester 在 水 作用下， 反应 4.0h， 以66%的产率得到苯氧基(苯基)次膦酸
  参考文献：
  名称：

  Korth, Hans-Gert; Lommes, Petra, Chemische Berichte, 1992, vol. 125, # 11, p. 2419 - 2438

  摘要：

  DOI：
• 作为产物：
  描述：

  苯氧基亚磷酰二氯 在 甲酸 作用下， 以 苯 为溶剂， 生成 Phenylchlorophosphonic Acid Phenyl Ester
  参考文献：
  名称：

  Kazantseva, M. V.; Timokhin, B. V.; Donskikh, V. I., Journal of general chemistry of the USSR, 1991, vol. 61, # 4.2., p. 932

  摘要：

  DOI：

文献信息

• Preparation of 3-substituted cephalosporins
  申请人：Lilly Industries Limited

  公开号：US04301280A1

  公开（公告）日：1981-11-17

  There is described a process for preparing an enamine of formula (IX): ##STR1## where R.sup.2 is a carboxylic acid protecting group and R.sup.3 is the residue of a carboxylic acid derived acyl group and where R.sup.5 and R.sup.6 are the same or different C.sub.1-4 alkyl or C.sub.7-10 aralkyl groups; or taken together with the adjacent nitrogen atom form a heterocyclic ring containing from 4 to 8 carbon atoms and optionally a further heteroatom selected from oxygen and nitrogen; by reacting a compound of formula (XII): ##STR2## with an amine of formula HNR.sup.5 R.sup.6, the reactant of formula (XII) being prepared by reaction of an appropriate enol derivative with a phosphorus reagent. The enamines of formula (IX) are useful in the preparation of 3-hydroxycephalosporins.

  描述了一种制备式（IX）的烯胺的过程：其中R.sup.2是羧酸保护基，R.sup.3是羧酸衍生酰基的残基，R.sup.5和R.sup.6是相同或不同的C.sub.1-4烷基或C.sub.7-10芳基烷基；或者与相邻的氮原子一起形成含有4至8个碳原子和可选地从氧和氮中选择的进一步杂原子的杂环环的异构体；通过将式（XII）的化合物与式HNR.sup.5 R.sup.6的胺反应，其中式（XII）的反应物是通过将适当的烯醇衍生物与磷试剂反应制备的。式（IX）的烯胺在3-羟基头孢菌素的制备中很有用。
• Electrophilic Catalysis in the Synthesis of Aryl Methyl- and Phenylphosphonochloridates
  作者：E. I. Goryunov、I. B. Goryunova、G. N. Molchanova、I. Yu. Kudryavtsev、T. V. Baulina、A. A. Khodak、T. V. Strelkova、V. K. Brel

  DOI：10.1134/s1070363218090025

  日期：2018.9

  The reaction of methyl- and phenylphosphonic dichlorides with phenols in the presence of anhydrous magnesium chloride as catalyst or magnesium metal as precatalyst provides a simple, efficient, and practical method of synthesis of the corresponding aryl methyl- and phenylphosphonochloridates.

  在无水氯化镁作为催化剂或金属镁作为预催化剂的存在下，甲基和苯基膦酰二氯与苯酚的反应提供了一种简单，有效且实用的合成相应的芳基甲基和苯基膦酰氯的方法。
• BONDABLE FLAME-RETARDANT VANILLIN-DERIVED MOLECULES
  申请人：International Business Machines Corporation

  公开号：US20180320073A1

  公开（公告）日：2018-11-08

  A flame-retardant vanillin-derived molecule, a process for forming a flame-retardant resin, and an article of manufacture comprising a material that contains the flame-retardant vanillin-derived molecule are disclosed. The flame-retardant vanillin-derived molecule can be synthesized from vanillin obtained from a bio-based source, and can have at least one phosphoryl or phosphonyl moiety with phenyl, allyl, epoxide, propylene carbonate, or thioether substituents. The process for forming the flame-retardant resin can include reacting a vanillin derivative and a flame-retardant phosphorus-based molecule to form the flame-retardant vanillin-derived molecule, and binding the flame-retardant vanillin-derived molecule to a resin. The flame-retardant vanillin-derived molecules can also be bound to polymers. The material in the article of manufacture can be flame-retardant, and contain the flame-retardant vanillin-derived molecules. Examples of materials that can be in the article of manufacture can include resins, plastics, adhesives, polymers, etc.

  本文揭示了一种阻燃香草醛衍生分子、形成阻燃树脂的方法，以及包含含有阻燃香草醛衍生分子的材料的制造物品。这种阻燃香草醛衍生分子可以从生物基来源中获得的香草醛合成，可以具有至少一个含有苯基、烯丙基、环氧、丙烯碳酸酯或硫醚取代基的磷酸酯或膦酰基团。形成阻燃树脂的方法可以包括将香草醛衍生物和阻燃磷基分子反应以形成阻燃香草醛衍生分子，并将其与树脂结合。阻燃香草醛衍生分子也可以与聚合物结合。制造物品中的材料可以是阻燃的，并含有阻燃香草醛衍生分子。制造物品中的材料可以包括树脂、塑料、粘合剂、聚合物等。
• N-Alkyl-N′-[(alkyl/aryl)(alkoxy/aroxy)phosphoryl]ureas: synthesis and extraction properties toward f-elements
  作者：E. I. Goryunov、T. V. Baulina、I. B. Goryunova、A. G. Matveeva、A. M. Safiulina、E. E. Nifant’ev

  DOI：10.1007/s11172-014-0408-y

  日期：2014.1

  Me, Ph). Their extraction capability toward UVI and a number of tervalent lanthanides (LaIII, NdIII, HoIII, YbIII) was studied. Efficiency and selectivity of these ligands in the extraction of f-elements from nitric acid solutions to chloroform were compared with extraction properties of a model phosphine oxide-type phosphorylurea MePhP(O)NHC(O)NHC8H17-n and carbamoylphosphine oxide Ph2P(O)CH2C(O)NBu2

  氯膦酸盐 R1R2P(O)Cl 与 NaOCN 的反应以及随后用辛胺处理导致磷酸脲 R1R2P(O)NHC(O)NHC8H17-n (R1 = EtO, PhO; R2 = Me, Ph)。研究了它们对 UVI 和许多三价镧系元素（LaIII、NdIII、HoIII、YbIII）的提取能力。将这些配体从硝酸溶液中提取 f 元素到氯仿的效率和选择性与模型氧化膦型磷酰脲 MePhP(O)NHC(O)NHC8H17-n 和氨基甲酰基氧化膦 Ph2P(O) 的提取特性进行了比较CH2C(O)NBu2。
• Catalytic synthesis of O-aryl methyl(phenyl)phosphonochloridates
  作者：V. K. Brel、E. I. Goryunov、G. N. Molchanova、I. B. Goryunova、I. Yu. Kudryavtsev、T. V. Baulina、A. A. Khodak、T. V. Strelkova、E. E. Nifant’ev

  DOI：10.1134/s001250081702001x

  日期：2017.2

  with phenols in the presence of anhydrous magnesium chloride (catalyst) or magnesium metal (procatalyst) has been used as a simple, efficient, and industrially feasible method for the synthesis of the corresponding O-aryl alkyl(aryl)phosphonochloridates.

  在无水氯化镁（催化剂）或金属镁（原催化剂）存在下，甲基和苯基二氯膦酸酯与苯酚的反应已被用作一种简单、有效且工业上可行的合成相应的 O-芳基烷基（芳基）的方法。 )膦酰氯。