(trifluoromethyl)cadmiumbromide | 97571-11-4

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氟化物
• 英文名称: (trifluoromethyl)cadmiumbromide
• 英文别名: trifluoromethylcadmium bromide
• CAS: 97571-11-4
• 化学式: CBrCdF₃
• 分子量: 261.32
• InChiKey: APVMYVQJRYACDO-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  6.0
• 可旋转键数：
  0.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0.0
• 氢给体数：
  0.0
• 氢受体数：
  0.0

反应信息

• 作为反应物：
  描述：

  (trifluoromethyl)cadmiumbromide 生成 三氟甲烷-D
  参考文献：
  名称：

  BURTON, D. J.;WIEMERS, D. M.;EASDON, J. C.

  摘要：

  DOI：
• 作为产物：
  描述：

  二溴二氟甲烷 生成 (trifluoromethyl)cadmiumbromide
  参考文献：
  名称：

  BURTON, D. J.;WIEMERS, D. M.;EASDON, J. C.

  摘要：

  DOI：

文献信息

• Nucleophilic substitution studies on nitroimidazoles, and applications to the synthesis of biologically active compounds
  作者：Gérard Chauvière、Cécile Viodé、Jacques Périé

  DOI：10.1002/jhet.5570370120

  日期：2000.1

  The rationalization of the synthesis of substituted analogs of megazol, a biologically active 5-nitroimidazole at position 4 of the imidazole ring, had led to the study of intermediate steps. The methylation by diazomethane of 2,4-(5)dihalogeno-5-(4)nitroimidazole is regioselective leading to 2,4-dihalogeno-1-methyl-5-nitroimidazole 2. On this compound 2, hard nucleophiles such as cyanide, methoxide

  合成的咪唑取代的类似物（咪唑环第4位具有生物活性的5-硝基咪唑）的合理化导致了中间步骤的研究。2,4-（5）二卤代-5-（4）硝基咪唑被重氮甲烷甲基化是区域选择性的，从而导致2,4-二卤代-1-甲基-5-硝基咪唑2。在该化合物2上，硬的亲核试剂如氰化物，甲醇根或氢化物阴离子仅在2位与卤素反应；而来自有机铜物种的柔软亲核试剂（例如胺，硫醇或三氟甲基阴离子）仅与中间体3b或化合物4b中位置4的卤素反应。
• Electrochemical and Chemical Syntheses of Trifluoromethylating Reagents and Trifluoromethyl Substituted Compounds
  作者：Joseph Grobe、Joachim Hegge

  DOI：10.1002/zaac.200800206

  日期：2008.9

  dissolution of the Al anode reaches 120 % indicating a considerable chemical corrosion in addition to the anodic oxidation. This result enabled a one-pot trifluoromethylation reaction of NMP as organic carbonyl substrate and solvent with CF3Br and aluminium powder (ratio 3 : 2) at higher temperatures (> 70 °C). The complete reaction of CF3Br to give CF3H and 1-methyl-2-trifluoromethyl-4,5-dihydropyrrol

  已在高压不锈钢高压釜中在不同阴极 [Pt、钢 (V2A、V4A)、玻璃碳 (GC)] 和各种支持溶剂的电解质系统 (SSE) 中研究了卤氟甲烷 Br、CF2Br2 和 CF2BrCl 的电还原，例如 DMF/[Bu4N]Br、NMP/[Bu4N]BF4 等。 Br 的还原电位从 Pt (–1.6 V) C–Cl > C–Br) 和“全氟效应”增加。我们的实验装置重新研究了在具有牺牲锌或镉阳极的不同 SSE 系统中对 Br 的电解，以阐明实验条件对产物类型和比例的影响。观察到的产物 MBr·42L 和 (CF3)2M·42L (M = Zn, Cd; L = DMF 或 AN) 与之前的研究相同，但以不同的比例获得，通常由相应阳极的平行化学腐蚀引起。通过使用铝作为牺牲阳极，不会形成 Al 化合物。 Br 电还原生成的 物种通过夺氢和形成 H 与溶剂反应。相对于铝阳极溶解的电流产率达到
• A remarkably simple preparation of (trifluoromethyl)cadmium and -zinc reagents directly from difluorodihalomethanes
  作者：Donald J. Burton、Denise M. Wiemers

  DOI：10.1021/ja00303a042

  日期：1985.8
• Bouillon, Jean-Philippe; Maliverney, Christian; Merenyi, Robert, Journal of the Chemical Society. Perkin transactions I, 1991, # 9, p. 2147 - 2149
  作者：Bouillon, Jean-Philippe、Maliverney, Christian、Merenyi, Robert、Viehe, Heinz G.

  DOI：——

  日期：——
• Synthesis and Characterization of β-Trifluoromethyl-<i>m</i><i>eso</i>-tetraphenylporphyrins
  作者：Yuichi Terazono、David Dolphin

  DOI：10.1021/jo020562w

  日期：2003.3.1

  beta-Trifluoromethyl-meso-tetraphenylporphyrins were synthesized to investigate the electronic and steric effects of the trifluoromethyl groups on the macrocycle. Preparation of these novel porphyrins was carried out by copper-assisted trifluoromethylation of beta-tetrabromo-meso-tetraphenylporphyrin metal complexes and in situ generated CF3Cu. For comparison, the beta-methyl analogues were also prepared. Analysis of beta-trifluoromethylporphyrins by UV-vis, NMR, and cyclic voltammetry (CV) showed that the electron-withdrawing effects of the trifluoromethyl groups on the antipodal pyrroles required the macrocycle to take a fixed 18pi-electron pathway. UV-vis, CV, and molecular modeling studies suggest that the novel porphyrins are distorted following introduction of trifluoromethyl groups onto the pyrrolic beta-position of meso-tetraphenylporphyrin. The pK(a) difference of beta-tetrakis(trifluoromethyl)-meso-tetraphenylporphyrin from that of DBU in CH2Cl2, obtained by spectrophotometric titration, affirms that it is one of the most electron-deficient porphyrins so far prepared.