1-bromo-4-(2-propoxy-ethyl)-benzene | 849807-29-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-bromo-4-(2-propoxy-ethyl)-benzene
• 英文别名: (2-(4-bromophenyl)-ethyl) propyl ether；4-Bromophenethyl alcohol, n-propyl ether；1-bromo-4-(2-propoxyethyl)benzene
• CAS: 849807-29-0
• 化学式: C₁₁H₁₅BrO
• 分子量: 243.143
• InChiKey: PXGBYOHKVLEGFN-UHFFFAOYSA-N

物化性质

• 沸点：
  272.7±15.0 °C(Predicted)
• 密度：
  1.251±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1-bromo-4-(2-propoxy-ethyl)-benzene 、 氰化锌 在 四(三苯基膦)钯 作用下， 以 N-甲基吡咯烷酮 为溶剂， 反应 4.0h， 以19%的产率得到4-(2-propoxy-ethyl)-benzonitrile
  参考文献：
  名称：

  EP1669348

  摘要：

  公开号：
• 作为产物：
  描述：

  4-溴苯乙醇 、 1-碘代丙烷 在 sodium hydride 作用下， 以 四氢呋喃 为溶剂， 以33%的产率得到1-bromo-4-(2-propoxy-ethyl)-benzene
  参考文献：
  名称：

  Organic semiconductors

  摘要：

  一种分子包括一个链状的核心区域，具有两个末端，至少有三个共轭芳香环；并且在两个末端分别包括分支基团R1和R2，每个基团包括一个C5到C20烷基基团。包括该分子的半导体组合物。

  公开号：

  US20070078267A1

文献信息

• Organic compositions
  申请人：Dotz Florian

  公开号：US20070075630A1

  公开（公告）日：2007-04-05

  Apparatus including a support body; and an organic semiconductor composition body including at least one of the group including polystyrene, poly(9,9′-dioctylfluorene-co-bithiophene) (“F8T2”) and a cellulose, and an organic molecule including a chain-like core region having two ends and having at least three conjugated aromatic rings; and including at the two ends, branched or unbranched groups R 1 and R 2 respectively, each including a branched or unbranched C 5 - to C 20 -alkyl group. Printing inks including such molecule.

  装置包括一个支撑体；以及一个有机半导体组分体，包括聚苯乙烯、聚（9,9′-二辛基芴-共-噻吩）（“F8T2”）和纤维素中至少一种的群体，以及一个有机分子，包括一个链状核心区域，其具有两个端点并且至少有三个共轭芳香环；并且在这两个端点上，分别包括分支或非分支基团R1和R2，每个基团包括分支或非分支的C5-C20烷基。这样的分子包括印刷油墨。
• Novel antifungal agent containing heterocyclic compound
  申请人：Nakamoto Kazutaka

  公开号：US20070105943A1

  公开（公告）日：2007-05-10

  The present invention provides an antifungal agent represented by the formula: [wherein A 1 represents a 3-pyridyl group which may have a substituent, a quinolyl group which may have a substituent, or the like; X 1 represents a group represented by the formula —NH—C(═O)—, a group represented by the formula —C(═O)—NH—, or the like; E represents a furyl group, a thienyl group, a pyrrolyl group, a phenyl group, a pyridyl group, a tetrazolyl group, a thiazolyl group or a pyrazolyl group; with the proviso that A 1 may have 1 to 3 substituents, and E has one or two substituents].

  本发明提供了一种抗真菌剂，其表示为以下式子： [其中A1表示一个3-吡啶基团，可能具有取代基，喹啉基团，可能具有取代基或类似物；X1表示由公式—NH—C（═O）—，由公式—C（═O）—NH—或类似物表示的基团；E表示呋喃基团，噻吩基团，吡咯基团，苯基团，吡啶基团，四唑基团，噻唑基团或吡唑基团；但A1可能具有1到3个取代基，E具有一个或两个取代基。]
• Novel Antimalarial Agent Containing Heterocyclic Compound
  申请人：Nakamoto Kazutaka

  公开号：US20090227799A1

  公开（公告）日：2009-09-10

  Disclosed is an antimalarial agent containing a compound represented by the formula: [wherein A 1 represents a 3-pyridyl group that may have a substituent, a 6-quinolyl group that may have a substituent, or the like; X 1 represents a group represented by the formula —C(═O)—NH— or the like; E represents a furyl group, a thienyl group or a phenyl group; with the proviso that A 1 may have one to three substituents, and E has one of two substituents] or a salt thereof or hydrates thereof.

  揭示了一种抗疟疾剂，其包含由下式表示的化合物： [其中A1表示一个3-吡啶基团，可以有取代基，一个6-喹啉基团，可以有取代基或类似物；X1表示一个由公式-C（═O）-NH-或类似物表示的基团；E表示一个呋喃基团，噻吩基团或苯基团；但前提是A1可以有1到3个取代基，E有两个取代基之一]或其盐或水合物。
• NOVEL ANTIFUNGAL AGENT CONTAINING HETEROCYCLIC COMPOUND
  申请人：NAKAMOTO Kazutaka

  公开号：US20110195999A1

  公开（公告）日：2011-08-11

  The present invention provides an antifungal agent represented by the formula: wherein A 1 represents a 3-pyridyl group which may have a substituent, a quinolyl group which may have a substituent, or the like; X 1 represents a group represented by the formula —NH—C(═O)—, a group represented by the formula —C(═O)—NH—, or the like; E represents a furyl group, a thienyl group, a pyrrolyl group, a phenyl group, a pyridyl group, a tetrazolyl group, a thiazolyl group or a pyrazolyl group; with the proviso that A 1 may have 1 to 3 substituents, and E has one or two substituents.

  本发明提供一种抗真菌剂，其化学式如下： 其中，A1代表3-吡啶基，可以有取代基，喹啉基，也可以有取代基等；X1代表由公式—NH—C（═O）—，由公式—C（═O）—NH—等表示的基团；E代表呋喃基，噻吩基，吡咯基，苯基，吡啶基，四唑基，噻唑基或吡唑基；但要求A1可能有1到3个取代基，E有1或2个取代基。
• Antifungal agent containing heterocyclic compound
  申请人：Eisai R&D Management Co., Ltd.

  公开号：US07932272B2

  公开（公告）日：2011-04-26

  The present invention provides an antifungal agent represented by the formula: [wherein A1 represents a 3-pyridyl group which may have a substituent, a quinolyl group which may have a substituent, or the like; X1 represents a group represented by the formula —NH—C(═O)—, a group represented by the formula —C(═O)—NH—, or the like; E represents a furyl group, a thienyl group, a pyrrolyl group, a phenyl group, a pyridyl group, a tetrazolyl group, a thiazolyl group or a pyrazolyl group; with the proviso that A1 may have 1 to 3 substituents, and E has one or two substituents].

  本发明提供了一种抗真菌剂，其化学式如下：[其中A1代表3-吡啶基，可以具有取代基，喹啉基，也可以具有取代基等；X1代表由公式—NH—C（═O）—，由公式—C（═O）—NH—等表示的基团；E代表呋喃基，噻吩基，吡咯基，苯基，吡啶基，四唑基，噻唑基或吡唑基；限制条件是A1可以有1到3个取代基，E有一个或两个取代基]。