bis(isopropylsalicylaldiminato)nickel(II) | 35968-67-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: bis(isopropylsalicylaldiminato)nickel(II)
• 英文别名: bis(N-isopropylsalicylideneiminato)nickel(II)；bis(N-(iso-propyl)salicylaldiminato)nickel(II)
• CAS: 35968-67-3
• 化学式: C₂₀H₂₄N₂NiO₂
• 分子量: 383.113
• InChiKey: SAYSBVLDFNIBSK-NVFNPILPSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  bis(isopropylsalicylaldiminato)nickel(II) 在 methanol 作用下， 以 甲醇 为溶剂， 生成
  参考文献：
  名称：

  The Occurrence of Paramagnetic Tetrahedral Forms of N-Arylsalicylaldiminonickel(II) Complexes in Solution at Elevated Temperatures

  摘要：

  DOI：

  10.1021/ja00895a011
• 作为产物：
  描述：

  水杨醛 以 甲醇 为溶剂， 反应 10.17h， 生成 bis(isopropylsalicylaldiminato)nickel(II)
  参考文献：
  名称：

  Synthesis, characterization, crystal structure and DNA, HSA-binding studies of four Schiff base complexes derived from salicylaldehyde and isopropylamine

  摘要：

  Four new Schiff base complexes (NiL2, CoL2, CuL2 and ZnL2) (HL: ((E)-2-((isopropylamino) methyl) phenol) were synthesized and characterized by CHN elemental analysis, FT-IR and single crystal X-ray diffraction technique. The crystallographic data reveal that in all complexes the metal centers are four-coordinated by two phenolate oxygen and two imine nitrogen atoms of two moles of Schiff base ligand HL and geometry around the metal center in all of them is distorted tetrahedral. In addition, H-1 and C-13 NMR techniques were employed for characterization of diamagnetic ZnL2 complex. The binding affinity of complexes with DNA (fish sperm DNA, FS-DNA) and Human Serum Albumin (HSA) were investigated using fluorescence quenching, chemometrics, UV-Vis spectroscopy, viscosity measurements and molecular docking methods. The obtained results revealed that the DNA and HSA affinity for binding to complexes are in the following order: CuL2 > ZnL2 > CoL2 > NiL2 and NiL2 > ZnL2 > CuL2 > CoL2. The distance between complexes and HSA was obtained based on the Forster's theory of non-radiative energy transfer. The computational molecular docking results showed that H-bond interactions, hydrophobic interactions, pi-pi stacking and pi-cation interactions have dominant role in the stability of HSA-ML2 (M: Cu, Co, Ni and Zn). The computational docking and viscosity results suggest that all metal complexes interact with DNA presumably by the groove binding mechanism. (c) 2017 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ica.2017.05.035

文献信息

• Mechanistic study of the transimination of bis(N-alkylsalicylaldiminato)nickel(II) with ammonium ion in acetonitrile
  作者：Laura Carbonaro、Ambrogio Giacomelli、Mauro Isola、Lucio Senatore

  DOI：10.1039/dt9920000037

  日期：——

  Electronic spectrophotometry has been empolyed to study the mechanism of transimination in bis(N-alkylsalicylaldiminato)nickel(II) complexes (alkyl = Me, Et, Pri, Prn or Bun) by ammonium ion in acetonitrile. The reaction is clearly biphasic: fast addition of ammonium and slow elimination of alkylammonium ions. The addition reaction involving the two azomethine bonds of the complex occurs by two consecutive

  电子分光光度法已empolyed研究transimination的在双机制（Ñ -alkylsalicylaldiminato）镍（II）配合物（烷基=甲基，乙基，镨我，镨Ñ或卜ñ）通过铵离子的乙腈。该反应显然是两相的：快速添加铵和缓慢消除烷基铵离子。涉及两个配合物的两个偶氮甲碱键的加成反应通过两个连续的过程发生，并且对于R = Bu n，发现了一个二项速率定律。在连续消除反应中，仅观察到一个速率常数，该常数取决于p K a和所留下的烷基铵离子的空间应变。
• Studies on Nickel(II) Complexes. VII. A Nuclear Resonance Investigation of Mixed Ligand Complexes
  作者：A. Chakravorty、R. H. Holm

  DOI：10.1021/ja01073a019

  日期：1964.10

  solutions of differently substituted bis(salicylaldimine)-Ni(II) complexes which are involved in a planar tetrahedral conformational equilibrium results in rapid and nearly statistical ligand exchange The mixed ligand complexes thus produced have been unambiguously identified by their proton resonance spectra which, like these of the pure complexes, exhibit characteristic isotropic proton hyperfine contact

  参与平面四面体构象平衡的不同取代的双（水杨醛二亚胺）-Ni（II）配合物的溶液的平衡导致快速且几乎统计的配体交换由此产生的混合配体配合物已通过其质子共振光谱明确识别，其中，像这些纯配合物一样，表现出特征性的各向同性质子超精细接触相互作用。测量了混合配合物中的自旋密度，与纯配合物的比较表明发生了自旋的不对称重新分布 将产生不对称自旋密度分布的最新模型应用于混合水杨二亚胺配合物 配体的可能机制 -讨论交换过程。
• Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: Ni: MVol.C2, 7.3, page 657 - 667
  作者：

  DOI：——

  日期：——
• Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: Ni: MVol.C2, 7.2, page 646 - 657
  作者：

  DOI：——

  日期：——
• Steric and conformational effects on the kinetics of ligand substitution in bis(salicylaldiminato)nickel(II) complexes
  作者：Manfred Schumann、Angela Von Holtum、Klaus J. Wannowius、Horst Elias

  DOI：10.1021/ic00132a028

  日期：1982.2