3β,17β-Dihydroxy-androst-5-en-7-on-oxim-3,17-diacetat | 6845-55-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 3β,17β-Dihydroxy-androst-5-en-7-on-oxim-3,17-diacetat
• 英文别名: 7-Oximino-3β,17β-diacetoxy-androst-5-en；3β.17β-diacetoxy-androsten-(5)-one-(7)-oxime；3β.17β-Diacetoxy-androsten-(5)-on-(7)-oxim；7-oximino-5-androstene-3β,17β-diyl diacetate；7-oximino-5-androstene-3β,17β-diol diacetate；7-Oximino-5-androstene-3beta,17beta-diol Diacetate；[(3S,8R,9S,10R,13S,14S,17S)-17-acetyloxy-7-hydroxyimino-10,13-dimethyl-1,2,3,4,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-yl] acetate
• CAS: 6845-55-2
• 化学式: C₂₃H₃₃NO₅
• 分子量: 403.519
• InChiKey: PRUBKNVJJOIBLD-GSLJADNHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  29
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  85.2
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  3β,17β-Dihydroxy-androst-5-en-7-on-oxim-3,17-diacetat 在 potassium carbonate 作用下， 以 丁酮 为溶剂， 反应 28.0h， 生成 7-[O-{3-(imidazol-1-yl)propyl}oximino]-5-androstene-3β,17β-diyl diacetate
  参考文献：
  名称：

  NOVEL SERIES OF IMIDAZOLYL SUBSTITUTED STEROIDAL AND INDAN-1-ONE DERIVATIVES

  摘要：

  公开号：

  EP1934241B1
• 作为产物：
  描述：

  3beta,17beta-二(乙酰氧基)-雄甾-5-烯-7-酮 在 吡啶 、 盐酸羟胺 作用下， 反应 2.0h， 以86.54%的产率得到3β,17β-Dihydroxy-androst-5-en-7-on-oxim-3,17-diacetat
  参考文献：
  名称：

  Novel Series of Imidazolyl Substituted Steroidal and Indan-1-One Derivatives

  摘要：

  本发明提供了一种新的咪唑基取代类固醇和茚环-1-酮衍生物及其盐，其具有以下一般结构式（A和B）。

  公开号：

  US20090137541A1

文献信息

• Imidazolyl substituted steroidal and indan-1-one derivatives
  申请人：Bansal Ranju

  公开号：US08361996B2

  公开（公告）日：2013-01-29

  The present invention provides a novel series of imidazolyl substituted steroidal and indan-1-one derivatives and salts thereof having the following general structural formulae (A and B)

  本发明提供了一种新型的咪唑基取代的类固醇和吲哚-1-酮衍生物及其盐，其具有以下一般结构式（A和B）：
• Water balance study and conjunctive water use planning in an irrigation canal command area: A remote sensing perspective
  作者：V. V. Rao、A. K. Chakraborti

  DOI：10.1080/014311600750019859

  日期：2000.1

  Water budgeting of the D-36 and D-36 A distributaries confined between Pedda Vagu, Korutla Vagu and Kakatiya main canal of the Sri RamSagar Project (SRSP) Command area was conducted using remote sensing derived crop areas, land cover information, irrigation tank inventory and source-wise distribution of irrigated areas, together with conventional meteorological, canal flows and well inventory data. A semi-empirical water balance model was developed and validated using remote sensing derived objective information of the command area and the validated model used for predicting the groundwater table under normal rainfall conditions. Recharge and water balance in the study area indicated that the net recharge to the aquifer is negative to the tune of 2.54 Mm(3) resulting in a fall of the groundwater table by 0.79 m during 1992-93. However, normalized groundwater recharge and water balance estimates indicate an impending waterlogging problem with an annual groundwater table rise of 0.35 m. In view of existing water management practices, a conjunctive water use plan of rotational operation of aquifers and canals is suggested.