(S)-2-((anthracen-9-ylmethylene)amino)-3-methylbutanoic acid | 1233344-15-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: (S)-2-((anthracen-9-ylmethylene)amino)-3-methylbutanoic acid
• CAS: 1233344-15-4
• 化学式: C₂₀H₁₉NO₂
• 分子量: 305.376
• InChiKey: GDOCGDLJGGGERW-IBGZPJMESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.52
• 重原子数：
  23.0
• 可旋转键数：
  4.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  49.66
• 氢给体数：
  1.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  (S)-2-((anthracen-9-ylmethylene)amino)-3-methylbutanoic acid 在 sodium tetrahydroborate 作用下， 以 甲醇 为溶剂， 反应 5.0h， 生成 C₂₀H₂₁NO₂
  参考文献：
  名称：

  Quencher displacement strategy for recognition of trivalent cations through ‘turn-on’ fluorescence signaling of an amino acid hybrid

  摘要：

  An in situ generated anthracene based hybrid amino acid 1-Cu2+ complex has been utilized efficiently as a light-up probe to detect biologically/environmentally important trivalent metal ions Fe3+/Cr3+/Al3+ through turn-on fluorescence signaling. Whereas the amino acid derivative 1 showed a poor selectivity toward various metal ions, the 1-Cu2+ ensemble showed a high selectivity toward trivalent cations. The enhancement in fluorescent intensity of 1-Cu2+ was due to the displacement of Cu2+ from 1-Cu2+ by Fe3+/Cr3+/Al3+. Interestingly, the displacement of a paramagnetic ion (Cu2+) by other paramagnetic ions (Fe3+/Cr3+) resulted in an increase in fluorescence intensity by many folds. The selectivity was established in the presence of a large number of different metal ions using various spectroscopic techniques. This 1-Cu2+ ensemble was also found to be a selective sensor for phosphate anion. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.06.091
• 作为产物：
  描述：

  L-缬氨酸 、 9-蒽甲醛 在 lithium hydroxide 作用下， 以 甲醇 为溶剂， 反应 12.0h， 生成 (S)-2-((anthracen-9-ylmethylene)amino)-3-methylbutanoic acid
  参考文献：
  名称：

  Quencher displacement strategy for recognition of trivalent cations through ‘turn-on’ fluorescence signaling of an amino acid hybrid

  摘要：

  An in situ generated anthracene based hybrid amino acid 1-Cu2+ complex has been utilized efficiently as a light-up probe to detect biologically/environmentally important trivalent metal ions Fe3+/Cr3+/Al3+ through turn-on fluorescence signaling. Whereas the amino acid derivative 1 showed a poor selectivity toward various metal ions, the 1-Cu2+ ensemble showed a high selectivity toward trivalent cations. The enhancement in fluorescent intensity of 1-Cu2+ was due to the displacement of Cu2+ from 1-Cu2+ by Fe3+/Cr3+/Al3+. Interestingly, the displacement of a paramagnetic ion (Cu2+) by other paramagnetic ions (Fe3+/Cr3+) resulted in an increase in fluorescence intensity by many folds. The selectivity was established in the presence of a large number of different metal ions using various spectroscopic techniques. This 1-Cu2+ ensemble was also found to be a selective sensor for phosphate anion. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.06.091