(1Z)-1-(diaminomethylidenehydrazinylidene)-2,3-dihydroindene-4-carboximidamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 茚满类
• 英文名称: (1Z)-1-(diaminomethylidenehydrazinylidene)-2,3-dihydroindene-4-carboximidamide
• 化学式: C₁₁H₁₄N₆
• 分子量: 230.27
• InChiKey: CYPGNVSXMAUSJY-SXGWCWSVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  127
• 氢给体数：
  4
• 氢受体数：
  3

文献信息

• Hair growth compositions and methods
  申请人：Pilosciences

  公开号：EP2735303A1

  公开（公告）日：2014-05-28

  The present invention relates to hair modifying compositions and methods, as well as to compositions and methods for modifying hair growth. The invention more specifically relates to targeted approaches using antibodies or agonists thereof for altering or stimulating hair growth, structure or number. The invention also relates to compositions, such as cosmetic compositions, comprising antibodies and/or further active agents, and their use to modify hair growth and/or to remove unwanted hair. The invention may be used in any mammalian subject, optionally in combination with any other depilation or hair stimulating method or any other hair treatment.

  本发明涉及毛发修饰组合物和方法，以及用于修饰毛发生长的组合物和方法。本发明更具体地涉及使用抗体或其激动剂改变或刺激毛发生长、结构或数量的靶向方法。本发明还涉及包含抗体和/或其他活性剂的组合物，如化妆品组合物，以及它们用于改变毛发生长和/或去除多余毛发的用途。本发明可用于任何哺乳动物，也可与任何其他脱毛或毛发刺激方法或任何其他毛发治疗方法结合使用。
• [EN] HAIR GROWTH COMPOSITIONS AND METHODS<br/>[FR] COMPOSITIONS ET PROCÉDÉS DE CROISSANCE PILEUSE
  申请人：PILOSCIENCES

  公开号：WO2014080015A2

  公开（公告）日：2014-05-30

  The present invention relates to hair modifying compositions and methods, as well as to compositions and methods for modifying hair growth. The invention more specifically relates to targeted approaches using antibodies or agonists thereof for altering or stimulating hair growth, structure or number. The invention also relates to compositions, such as cosmetic compositions, comprising antibodies and/or further active agents, and their use to modify hair growth and/or to remove unwanted hair. The invention may be used in any mammalian subject, optionally in combination with any other depilation or hair stimulating method or any other hair treatment.