(E)-1-ethoxy-1,2,3,3,3-pentafluoro-propene | 18316-14-8

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 乙烯基卤化物
• 英文名称: (E)-1-ethoxy-1,2,3,3,3-pentafluoro-propene
• 英文别名: (E)-1-ethoxy-1,2,3,3,3-pentafluoroprop-1-ene
• CAS: 18316-14-8
• 化学式: C₅H₅F₅O
• 分子量: 176.086
• InChiKey: JAZOPEQWWDRRSN-ARJAWSKDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  1,1,2,3,3,3-五氟丙基乙醚 在 lithium diisopropyl amide 作用下， 以 乙醚 、 正己烷 为溶剂， 反应 2.0h， 生成 (E)-1-ethoxy-1,2,3,3,3-pentafluoro-propene 、 1-丙烯,1-乙氧基-1,2,3,3,3-五氟-,(1Z)-
  参考文献：
  名称：

  Transformation de l'hexafluoropropène en alcool trifluoroallylique, précurseur des α-fluoroacrylates

  摘要：

  The alpha-fluoroacryloyl fluoride precursor of alpha-fluoroacrylic acid esters can arise from an allylic transposition of trifluoroallylic alcohol of which two methods of preparation are presented. In the first, dehydrofluoration of the alcohol CF3CFHCH(3)OH (4) is used. This alcohol is generated from the ester CF3CFHCOOC2H5 (3). In the second, dehalogenation of the alcohol CF3CFBrCH2OH (10) by zinc is used. The latter is formed by the selective reduction of the ester CF(3)CFBrCOOC2H(5) (9).

  DOI：

  10.1016/0022-1139(95)03289-p

文献信息

• Transformation de l'hexafluoropropène en alcool trifluoroallylique, précurseur des α-fluoroacrylates
  作者：Thoai Nguyen、Claude Wakselman

  DOI：10.1016/0022-1139(95)03289-p

  日期：1995.10

  The alpha-fluoroacryloyl fluoride precursor of alpha-fluoroacrylic acid esters can arise from an allylic transposition of trifluoroallylic alcohol of which two methods of preparation are presented. In the first, dehydrofluoration of the alcohol CF3CFHCH(3)OH (4) is used. This alcohol is generated from the ester CF3CFHCOOC2H5 (3). In the second, dehalogenation of the alcohol CF3CFBrCH2OH (10) by zinc is used. The latter is formed by the selective reduction of the ester CF(3)CFBrCOOC2H(5) (9).