1,1'-(1,3-phenylene)bis[2-(5-methyl-2-nitrophenyl)ethanol] | 1227098-14-7

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二芳基庚烷
• 英文名称: 1,1'-(1,3-phenylene)bis[2-(5-methyl-2-nitrophenyl)ethanol]
• 英文别名: 1-[3-[1-Hydroxy-2-(5-methyl-2-nitrophenyl)ethyl]phenyl]-2-(5-methyl-2-nitrophenyl)ethanol；1-[3-[1-hydroxy-2-(5-methyl-2-nitrophenyl)ethyl]phenyl]-2-(5-methyl-2-nitrophenyl)ethanol
• CAS: 1227098-14-7
• 化学式: C₂₄H₂₄N₂O₆
• 分子量: 436.464
• InChiKey: OHXKBAIBQSNDRG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  32
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  132
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  间苯二甲醛 、 5-甲基-2-硝基苄氯 在 四(二甲氨基)乙烯 、 sodium iodide 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 26.0h， 以54%的产率得到1,1'-(1,3-phenylene)bis[2-(5-methyl-2-nitrophenyl)ethanol]
  参考文献：
  名称：

  First TDAE-Mediated Double Addition of Nitrobenzylic Anions to Aromatic Dialdehydes

  摘要：

  We report herein the first tetrakis(dimethylamino) ethylene (TDAE)-mediated double addition of nitrobenzylic anions to aromatic dialdehydes such as terephthalaldehyde and isophthalaldehyde, and have developed a new methodology that allows us to observe the double addition. This TDAE-mediated approach is an original and mild method with which to generate tri-aromatic diols.

  DOI：

  10.1055/s-0029-1218590

文献信息

• First TDAE-Mediated Double Addition of Nitrobenzylic Anions to Aromatic Dialdehydes
  作者：Patrice Vanelle、Thierry Juspin、Gamal Giuglio-Tonolo、Thierry Terme

  DOI：10.1055/s-0029-1218590

  日期：2010.3

  We report herein the first tetrakis(dimethylamino) ethylene (TDAE)-mediated double addition of nitrobenzylic anions to aromatic dialdehydes such as terephthalaldehyde and isophthalaldehyde, and have developed a new methodology that allows us to observe the double addition. This TDAE-mediated approach is an original and mild method with which to generate tri-aromatic diols.