2-Cyclopropyl-2-[2-methoxy-5-[2-(2,4,6-trimethoxyphenyl)ethynylsulfonylmethyl]anilino]acetic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-Cyclopropyl-2-[2-methoxy-5-[2-(2,4,6-trimethoxyphenyl)ethynylsulfonylmethyl]anilino]acetic acid
• 英文别名: 2-cyclopropyl-2-[2-methoxy-5-[2-(2,4,6-trimethoxyphenyl)ethynylsulfonylmethyl]anilino]acetic acid
• 化学式: C₂₄H₂₇NO₈S
• 分子量: 489.5
• InChiKey: YTRUESDWMPFGOZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  34
• 可旋转键数：
  11
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  129
• 氢给体数：
  2
• 氢受体数：
  9

文献信息

• SUBSTITUTED ALKYL DIARYL DERIVATIVES, METHODS OF PREPARATION AND USES
  申请人：Temple University - Of The Commonwealth System of Higher Education

  公开号：EP2897599A2

  公开（公告）日：2015-07-29
• [EN] SUBSTITUTED ALKYL DIARYL DERIVATIVES, METHODS OF PREPARATION AND USES<br/>[FR] DÉRIVÉS ALKYL DIARYLES SUBSTITUÉS, PROCÉDÉS DE PRÉPARATION ET D'UTILISATIONS
  申请人：UNIV TEMPLE

  公开号：WO2014047110A2

  公开（公告）日：2014-03-27

  Compounds according to Formula I are provided: and salts thereof, wherein Q1, Q2, R3, R4, X, and Y are as defined herein. Methods for preparing compounds of Formula I are also provided, as well as methods of treating cellular proliferative disorders, such as cancer, using compounds of Formula (I).