N-methyl-3-[2-[2-(methylamino)ethoxy]ethoxy]propanamide

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N-methyl-3-[2-[2-(methylamino)ethoxy]ethoxy]propanamide
• 化学式: C₉H₂₀N₂O₃
• 分子量: 204.27
• InChiKey: LNVKPOSGPPEHLP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.3
• 重原子数：
  14
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  59.6
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Cell separation method using a release system for cell-antibody-substrate conjugates containing a polyethylene glycol spacer unit
  申请人：Miltenyi Biotec GmbH

  公开号：US20140113315A1

  公开（公告）日：2014-04-24

  The invention is directed to a releasable conjugate comprising a biotinylated ligand having a biotin moiety, a ligand moiety (Ligand 1 ) and a biotin-binding molecule (bbm) bound to the biotin moiety of the biotinylated ligand. The ligand moiety of the biotinylated ligand may be separated by a spacer group consisting of polyethylene glycol. Furthermore, the invention relates to a method for cleaving the releasable conjugate by providing biotin or streptavidin and an auxiliary release agent in a sufficient concentration to displace the biotin-binding molecule (bbm) from the biotin moiety of the biotinylated ligand and a method for separation of target cells from a cell sample utilizing the conjugate.
• CELL SEPARATION METHOD USING A RELEASE SYSTEM FOR CELL-ANTIBODY-SUBSTRATE CONJUGATES CONTAINING A POLYETHYLENE GLYCOL SPACER UNIT
  申请人：Miltenyi Biotec GmbH

  公开号：US20160298105A1

  公开（公告）日：2016-10-13

  The invention is directed to a releasable conjugate comprising a biotinylated ligand having a biotin moiety, a ligand moiety (Ligand 1 ) and a biotin-binding molecule (bbm) bound to the biotin moiety of the biotinylated ligand. The ligand moiety of the biotinylated ligand may be separated by a spacer group consisting of polyethylene glycol. Furthermore, the invention relates to a method for cleaving the releasable conjugate by providing biotin or streptavidin and an auxiliary release agent in a sufficient concentration to displace the biotin-binding molecule (bbm) from the biotin moiety of the biotinylated ligand and a method for separation of target cells from a cell sample utilizing the conjugate.