(2R)-5-pyridin-2-yl-1-[4-(5-pyridin-2-ylpentoxy)phenoxy]pentan-2-ol

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: (2R)-5-pyridin-2-yl-1-[4-(5-pyridin-2-ylpentoxy)phenoxy]pentan-2-ol
• 化学式: C₂₆H₃₂N₂O₃
• 分子量: 420.5
• InChiKey: OERBRSVNNWHZLL-XMMPIXPASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  31
• 可旋转键数：
  14
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  64.5
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• MEDICAMENT FOR LIVER REGENERATION AND FOR TREATMENT OF LIVER FAILURE
  申请人：Zender Lars

  公开号：US20140141510A1

  公开（公告）日：2014-05-22

  The present invention relates to the use of a compound which inhibits the activity of MKK4 as a medicament for the treatment of a patient suffering from an impaired liver function, to the use of a compound as a medicament for the treatment of liver failure, including acute/fulminant or chronic liver failure and/or for increasing the regeneration of liver tissue in a patient.