2-[(1Z,3E)-4-methoxybuta-1,3-dienyl]-1H-pyrrole

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: 2-[(1Z,3E)-4-methoxybuta-1,3-dienyl]-1H-pyrrole
• 化学式: C₉H₁₁NO
• 分子量: 149.19
• InChiKey: HGOKSWLYSCPIGC-IEQZRIFLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  25
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• CYCLIC PEPTIDE FROM NONOMURAEA SP., PROCESS FOR THE PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION FOR THE PREVENTION OR TREATMENT OF MYCOBACTERIA RELATED DISEASE COMPRISING THE SAME
  申请人：Kim Jong Woo

  公开号：US20140142031A1

  公开（公告）日：2014-05-22

  The present invention relates to novel anti-TB cyclic peptides from Nonomuraea sp. MJM5123, a process for the production of the anti-Tuberculosis peptide and a pharmaceutical composition for the prevention and treatment of mycobacterial infection comprising the same. The composition of the present invention is highly active against replicating/non-replicating M. tuberculosis , including MDR and XDR strains, so that it can be effectively used as a therapeutic agent for tuberculosis.
• US9090667B2
  申请人：——

  公开号：US9090667B2

  公开（公告）日：2015-07-28