(2S)-2,6-diamino-N-[(Z)-octadec-9-enyl]hexanamide

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (2S)-2,6-diamino-N-[(Z)-octadec-9-enyl]hexanamide
• 化学式: C₂₄H₄₉N₃O
• 分子量: 395.7
• InChiKey: DOOAAWNUOXWZEH-AXKWSIDASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  28
• 可旋转键数：
  21
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  81.1
• 氢给体数：
  3
• 氢受体数：
  3

文献信息

• Formulations and carrier systems including compound interactive domains
  申请人：University of Pittsburgh—Of The Commonwealth System of Higher Education

  公开号：US10172795B2

  公开（公告）日：2019-01-08

  A method of creating a formulation for a compound includes determining a compound interactive agent comprising at least one group that interacts with the compound, creating a carrier agent by conjugating at least one compound interactive domain comprising the at least one group that interacts with the compound with at least one hydrophilic domain, and combining the compound and the carrier agent to create the formulation. Creating the carrier agent may further include conjugating the at least one compound interactive domain with at least one hydrophobic domain so that the at least one compound interactive domain is positioned between the at least one hydrophilic domain and the at least one hydrophobic domain.

  一种为化合物配制制剂的方法包括：确定一种包含至少一个与化合物相互作用的基团的化合物相互作用剂，通过将包含至少一个与化合物相互作用的基团的至少一个化合物相互作用结构域与至少一个亲水结构域共轭来配制载体制剂，以及将化合物与载体制剂结合来配制制剂。制造载体制剂可进一步包括将至少一个化合物相互作用结构域与至少一个疏水结构域共轭，使至少一个化合物相互作用结构域位于至少一个亲水结构域和至少一个疏水结构域之间。
• FORMULATIONS AND CARRIER SYSTEMS INCLUDING COMPOUND INTERACTIVE DOMAINS
  申请人：University of Pittsburgh - Of the Commonwealth System of Higher Education

  公开号：EP2931260A1

  公开（公告）日：2015-10-21
• [EN] FORMULATIONS AND CARRIER SYSTEMS INCLUDING COMPOUND INTERACTIVE DOMAINS<br/>[FR] FORMULATIONS ET SYSTÈMES DE SUPPORT COMPRENANT DES DOMAINES INTERACTIFS DE COMPOSÉ
  申请人：UNIV PITTSBURGH

  公开号：WO2014093631A1

  公开（公告）日：2014-06-19

  A method of creating a formulation for a compound includes determining a compound interactive agent comprising at least one group that interacts with the compound, creating a carrier agent by conjugating at least one compound interactive domain comprising the at least one group that interacts with the compound with at least one hydrophilic domain, and combining the compound and the carrier agent to create the formulation. Creating the carrier agent may further include conjugating the at least one compound interactive domain with at least one hydrophobic domain so that the at least one compound interactive domain is positioned between the at least one hydrophilic domain and the at least one hydrophobic domain.