2,2,3,3-tetrafluoro(113C)propyl 2,2,3-trideuteriopropanoate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2,2,3,3-tetrafluoro(113C)propyl 2,2,3-trideuteriopropanoate
• 化学式: C6H8F4O2
• 分子量: 192.13
• InChiKey: OWMGACMLFUFHHT-GOULVKIXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  6

文献信息

• METHODS AND APPARATUS FOR PASADENA HYPERPOLARIZATION
  申请人：Huntington Medical Research Institutes

  公开号：US20150022204A1

  公开（公告）日：2015-01-22

  The present subject matter relates to methods and apparatus for using hyperpolarization to improve imaging. Am exemplary embodiment, a PASADENA polarizer, is capable of delivering 2.5-5 ml of highly hyperpolarized biological 13 C and 15 N imaging reagents in less than one minute, and capable of repeated delivery every 5-8 minutes. Exemplary quality control sequences are also provided to create versatile methods, systems, and apparatuses for a variety of biomolecules, capable of undergoing reaction with parahydrogen necessary for effective PASADENA. The subject matter simplifies the technology for routine liquid state generation of hyperpolarized molecules for 13 C and 15 N subsecond imaging and spectroscopy in vivo and further advance the clinical application of this technology. Methods and systems for providing magnetic shielding are also provided.
• US8766633B2
  申请人：——

  公开号：US8766633B2

  公开（公告）日：2014-07-01
• US9207296B2
  申请人：——

  公开号：US9207296B2

  公开（公告）日：2015-12-08