(4S)-4-amino-6-methyl-5-oxooctanoic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (4S)-4-amino-6-methyl-5-oxooctanoic acid
• 化学式: C₉H₁₇NO₃
• 分子量: 187.24
• InChiKey: QVHHEMGELQSBMM-MLWJPKLSSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2
• 重原子数：
  13
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  80.4
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• METHODS AND COMPOSITIONS FOR TREATING DISEASES TARGETING MABA
  申请人：Celera Corporation

  公开号：US20140178362A1

  公开（公告）日：2014-06-26

  Methods and compositions for detecting and treating a disease, particularly cancer, associated with differential expression of Maba in disease cells compared to healthy cells. Also provided are antagonists or agonists of Maba, and methods for screening agents that modulate the Maba level or activity in vivo or in vitro.