2,3-bis[[(Z)-octadec-9-enoyl]oxy]propoxyphosphinous acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2,3-bis[[(Z)-octadec-9-enoyl]oxy]propoxyphosphinous acid
• 化学式: C₃₉H₇₃O₆P
• 分子量: 669.0
• InChiKey: LXNCXRQXIUJDRC-CLFAGFIQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  14.3
• 重原子数：
  46
• 可旋转键数：
  38
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.85
• 拓扑面积：
  82.1
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• FC-FUNCTION ASSAY
  申请人：Henry Stephen Micheal

  公开号：US20140206019A1

  公开（公告）日：2014-07-24

  The present invention discloses a method of assaying Fc-function in an immunoglobulin containing sample by contacting the sample, in the presence of a complement, with red blood cells modified to incorporate a F-S-L peptide-lipid construct. The F-S-L peptide construct comprises a functional group (F) that is a target antigen for a complement activating immunoglobulin, a spacer group (S) covalently linking F to L and a lipid group (L). The present invention further discloses a specific construct, DOPE-Ad-CMG(2)-hCMV2 where the F group is an antigen of cytomegalovirus, that is used in assaying the Fc function of an intravenous immunoglobulin (IVIG) product.