9,16-Dihydroxy-4,6,10-trimethyl-17-propyl-14,18-dioxatricyclo[11.2.2.14,8]octadec-1(16)-ene-11,15-dione

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡喃
• 英文名称: 9,16-Dihydroxy-4,6,10-trimethyl-17-propyl-14,18-dioxatricyclo[11.2.2.14,8]octadec-1(16)-ene-11,15-dione
• 英文别名: 9,16-dihydroxy-4,6,10-trimethyl-17-propyl-14,18-dioxatricyclo[11.2.2.14,8]octadec-1(16)-ene-11,15-dione
• 化学式: C₂₂H₃₄O₆
• 分子量: 394.5
• InChiKey: GYQDICYCLLDJFP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  28
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  93.1
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• NOVEL MANGROMICIN COMPOUND AND PRODUCTION METHOD THEREFOR
  申请人：Omura Satoshi

  公开号：US20140206889A1

  公开（公告）日：2014-07-24

  [Problem] The present invention addresses the problem of providing an anti-trypanosomal drug having a novel skeleton, in order to solve issues that occur with conventional technologies. [Solution] The present invention is based on the discovery of a microbe that produces an anti-trypanosomal drug having a novel skeleton. Specifically, this invention provides: a compound indicated by formula (I) having a trypanosomal inhibitory activity; an analog thereof; a production method therefor; and a Lechevalieria sp. Kl0-0216 strain that produces said compound.
• US9000194B2
  申请人：——

  公开号：US9000194B2

  公开（公告）日：2015-04-07