(3S)-3-amino-5-methylsulfanylpent-1-ene-2-thiol

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醇
• 英文名称: (3S)-3-amino-5-methylsulfanylpent-1-ene-2-thiol
• 化学式: C₆H₁₃NS₂
• 分子量: 163.3
• InChiKey: PWTYVNBZOROVLG-LURJTMIESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  9
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  52.3
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME
  申请人：DOOSAN CORPORATION

  公开号：US20150318483A1

  公开（公告）日：2015-11-05

  The present disclosure relates to a novel compound having excellent hole injection capabilities and transport capabilities, light-emitting capabilities, and the like, and an organic electroluminescent device which includes the compound in one or more organic material layers thereof so as to improve characteristics such as light-emitting efficiency, driving voltage, and a service life.

  本公开涉及一种具有优异的空穴注入能力和传输能力、发光能力等的新型化合物，以及包括该化合物在一个或多个有机材料层中的有机电致发光器件，以改善其发光效率、驱动电压和使用寿命等特性。
• BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION
  申请人：Gilead Sciences, Inc.

  公开号：EP3070081A1

  公开（公告）日：2016-09-21

  Compounds disclosed herein including compounds of formula I': and salts thereof are provided. Pharmaceutical compositions comprising compounds disclosed herein, processes for preparing compounds disclosed herein, intermediates useful for preparing compounds disclosed herein and therapeutic methods for treating an HIV infection using compounds disclosed herein are also provided.

  本文公开的化合物包括式 I' 的化合物： 及其盐类。还提供了包含本文公开的化合物的药物组合物、制备本文公开的化合物的工艺、用于制备本文公开的化合物的中间体以及使用本文公开的化合物治疗 HIV 感染的治疗方法。
• 9-(1H-IMIDAZOL-5-YL)-1,11-DIHYDROISOCHROMENO[4',3':6,7]NAPHTHO[1,2-D]IMIDAZOLE DERIVATIVES AND THEIR USE AS INHIBITORS OF HCV NS5A
  申请人：Gilead Pharmasset LLC

  公开号：EP3239153A1

  公开（公告）日：2017-11-01

  The disclosure is related to anti-viral compounds of formula (I)         E1a-V1a-C(=O)-P1a-W1a-P1b-C(=O)-V1b-E1b     (I) wherein W1a is wherein Y5 is -CH 2-O- or -C(=O)-O-; X5 is -CH=CH-; and W1a is optionally substituted with halo or alkyl; and to compositions containing such compounds for use in the prophylactic or therapeutic treatment of hepatitis C.

  本公开涉及式 (I) 的抗病毒化合物 E1a-V1a-C(=O)-P1a-W1a-P1b-C(=O)-V1b-E1b (I) 其中 W1a 是 其中 Y5 是-CH 2-O- 或-C(=O)-O-； X5是-CH=CH-；和 W1a任选被卤素或烷基取代； 以及含有此类化合物的用于丙型肝炎预防或治疗的组合物。
• PYRIDONE DERIVATIVES FOR MODULATING STRESS-ACTIVATED PROTEIN KINASE SYSTEM
  申请人：Intermune, Inc.

  公开号：EP1928454B1

  公开（公告）日：2014-09-24
• CYCLIC PEPTIDES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF THE PLATELET ADHESION
  申请人：Klingler Otmar

  公开号：US20140011734A1

  公开（公告）日：2014-01-09

  The present invention relates to compounds of the Formula (I), in which R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17, R18, X1, X2, X3 and X4 have the meanings indicated in the claims, and which are valuable pharmacologically active compounds. They are reversible inhibitors of the interaction between the plasma protein von Willebrand factor (vWF) and the blood platelet receptor glycoprotein Ib-IX-V complex (GPIb), and are suitable, for example, for the therapy and prophylaxis of athero-thrombotic diseases. The invention furthermore relates to processes for the preparation of compounds of the Formula (I), their use, in particular as active ingredients in medicaments, and pharmaceutical compositions comprising them.