(2S)-2-amino-5-(diaminomethylideneamino)pentanoic acid;butane

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (2S)-2-amino-5-(diaminomethylideneamino)pentanoic acid;butane
• 化学式: C10H24N4O2
• 分子量: 232.32
• InChiKey: RJBSNPKTMTWUQC-WCCKRBBISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.26
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  128
• 氢给体数：
  4
• 氢受体数：
  4

文献信息

• POLY(ESTER AMIDE)S AND POLY(ESTER ETHER AMIDE)S WITH ALIPHATIC POLYESTERS, METHOD OF MAKING SAME, AND USES THEREOF
  申请人：Chu Chih-Chang

  公开号：US20140213738A1

  公开（公告）日：2014-07-31

  Polymers and copolymers having one or more aliphatic polyester groups or blocks. For example, the aliphatic polyester groups or blocks can be derived from a caprolactone such as, for example, ε-caprolactone. The polymers and copolymers can have desirable properties such as, for example, improved solubility and improved thermal properties.
• [EN] CATIONIC MATERIALS AND FORMULATIONS FOR DRUG DELIVERY<br/>[FR] MATÉRIAUX CATIONIQUES ET FORMULATIONS POUR L'ADMINISTRATION DE MÉDICAMENTS
  申请人：BRIGHAM & WOMENS HOSPITAL

  公开号：WO2015099985A2

  公开（公告）日：2015-07-02

  Cationic polymers are provided for delivering anionic active agents, preferably in the form or nanoparticles and other nanostructures. The polymer can be a polycation homopolymer or a copolymer containing a polycation block. The polycations and polycation containing polymers can contain dicarboxylic acid ester units and units of (a-amino acid)-α, ω- alkylene diester units. The nanoparticles can contain high loadings of anionic active agents, with sustained release of the active agents. Methods of making the polycations and polycation containing polymers are provided. Methods of making the nanoparticles and formulating them for administration to an individual in need thereof are also provided.