(1-Chloro-4-methyl-1-oxopentan-2-yl)carbamic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (1-Chloro-4-methyl-1-oxopentan-2-yl)carbamic acid
• 英文别名: (1-chloro-4-methyl-1-oxopentan-2-yl)carbamic acid
• 化学式: C₇H₁₂ClNO₃
• 分子量: 193.63
• InChiKey: MNNPIYWQDUYEKI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  66.4
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• [EN] QUINAZOLINE-BASED KINASE INHIBITORS<br/>[FR] INHIBITEURS DE KINASES À BASE DE QUINAZOLINE
  申请人：BRISTOL MYERS SQUIBB CO

  公开号：WO2016053794A1

  公开（公告）日：2016-04-07

  The present disclosure is generally directed to compounds which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAK1.

  本公开涉及一般用于抑制AAK1（适配器相关激酶1）的化合物，包括这种化合物的组合物，以及抑制AAK1的方法。
• ARYL AMIDE-BASED KINASE INHIBITORS
  申请人：BRISTOL-MYERS SQUIBB COMPANY

  公开号：US20160016967A1

  公开（公告）日：2016-01-21

  The present disclosure is generally directed to compounds which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAK1.

  本公开涉及一种可以抑制AAK1（适配器相关激酶1）的化合物，包括该化合物的组合物和抑制AAK1的方法。
• 5H-CHROMENO[3,4-C]PYRIDINES AS INHIBITORS OF ADAPTOR ASSOCIATED KINASE 1 (AAK1)
  申请人：Bristol-Myers Squibb Company

  公开号：EP2958924B1

  公开（公告）日：2016-12-28
• EP3200797A1
  申请人：——

  公开号：EP3200797A1

  公开（公告）日：2017-08-09
• QUINAZOLINE-BASED KINASE INHIBITORS
  申请人：Bristol-Myers Squibb Company

  公开号：US20170239249A1

  公开（公告）日：2017-08-24

  The present disclosure is generally directed to compounds which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAK1.