5-Ethylsulfanylcarbothioylsulfanylpentanoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 5-Ethylsulfanylcarbothioylsulfanylpentanoic acid
• 英文别名: 5-ethylsulfanylcarbothioylsulfanylpentanoic acid
• 化学式: C₈H₁₄O₂S₃
• 分子量: 238.4
• InChiKey: GHPAETCYWYEXRK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  13
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  120
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• NANOPARTICLES FOR CONTROLLED RELEASE OF ANTI-BIOFILM AGENTS
  申请人：University of Rochester

  公开号：EP2958557A1

  公开（公告）日：2015-12-30
• Nanoparticles for Controlled Release of Anti-Biofilm Agents and Methods of Use
  申请人：Koo Hyun

  公开号：US20150374634A1

  公开（公告）日：2015-12-31

  The present invention relates to compositions and methods to treat and/or prevent biofilms and biofilm related diseases. The invention comprises a nanoparticle carrier (NPC) and at least one therapeutic agent therein. The NPC binds within biofilm and to surfaces at risk for biofilm formation and accumulation while providing local, sustained, enhanced and controlled delivery of the therapeutic agent, when triggered for release. In one embodiment, the NPC comprises pH-responsive elements that allows for specific delivery of the therapeutic agent when the local environment dictates that the agent should be delivered precisely when it is most needed.
• US9566247B2
  申请人：——

  公开号：US9566247B2

  公开（公告）日：2017-02-14
• [EN] NANOPARTICLES FOR CONTROLLED RELEASE OF ANTI-BIOFILM AGENTS<br/>[FR] NANOPARTICULES POUR LA LIBÉRATION CONTRÔLÉE D'AGENTS ANTI-FILM BIOLOGIQUE
  申请人：UNIV ROCHESTER

  公开号：WO2014130994A1

  公开（公告）日：2014-08-28

  The present invention relates to compositions and methods to treat and/or prevent biofilms and biofilm related diseases. The invention comprises a nanoparticle carrier (NPC) and at least one therapeutic agent therein. The NPC binds within biofilm and to surfaces at risk for biofilm formation and accumulation while providing local, sustained, enhanced and controlled delivery of the therapeutic agent, when triggered for release. In one embodiment, the NPC comprises pH-responsive elements that allows for specific delivery of the therapeutic agent when the local environment dictates that the agent should be delivered precisely when it is most needed.
• [EN] NANOPARTICLES FOR CONTROLLED RELEASE OF ANTI-BIOFILM AGENTS AND METHODS OF USE<br/>[FR] NANOPARTICULES POUR LA LIBÉRATION CONTRÔLÉE D'AGENTS ANTI-BIOFILM ET PROCÉDÉS D'UTILISATION
  申请人：UNIV ROCHESTER

  公开号：WO2018026764A1

  公开（公告）日：2018-02-08

  The present invention relates to compositions and methods to treat and/or prevent biofilms and biofilm related diseases. The invention comprises a nanoparticle carrier (NPC) and at least one therapeutic agent therein. The NPC binds within biofilm and to surfaces at risk for biofilm formation and accumulation while providing local, sustained, enhanced and controlled delivery of the therapeutic agent, when triggered for release. In one embodiment, the NPC comprises pH-responsive elements that allows for specific delivery of the therapeutic agent when the local environment dictates that the agent should be delivered precisely when it is most needed.