6-amino-N-[5-amino-6-bis(phosphanyl)phosphanyl-6-oxohexyl]-2-methylhexanamide

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 6-amino-N-[5-amino-6-bis(phosphanyl)phosphanyl-6-oxohexyl]-2-methylhexanamide
• 化学式: C₁₃H₃₀N₃O₂P₃
• 分子量: 353.32
• InChiKey: LBKUECWRUQLQHJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.4
• 重原子数：
  21
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.85
• 拓扑面积：
  98.2
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• Enzyme-Degradable Polymer and Application Thereof
  申请人：Dai Lijun

  公开号：US20140243429A1

  公开（公告）日：2014-08-28

  The present invention belongs to the biomedicine field and specifically concerns an enzyme-degradable polymer and the application thereof. To solve the problem of low sensitivity of the existing assay reagents, the present invention provides an enzyme-degradable polymer and the related application of the polymer. The present invention also provides hydrogels, nano-particles, fluorescent dye-labeled enzyme substrates and kits (packages) for detection or activity-analysis of biological enzymes based on the enzyme-degradable polymer. The formula of the enzyme-degradable polymer is P 1 -(aa) N -(AA) n -X X=[formula 1] wherein, (aa) N is a non-enzyme substrate domain, the N aa may be different (no correlation), and N is a non-negative integer; (AA) n is an enzyme substrate domain, the n AA may be different, and n is a non-negative integer; P 1 is a protecting group of α-amino or functional group; P 2 is a protecting group of α-amino; P 3 is —NH 2 , a small molecule compound or a fragment of a polymer.
• US9200033B2
  申请人：——

  公开号：US9200033B2

  公开（公告）日：2015-12-01