Magnesium;2-hydroxy-2-[2-oxo-2-(1,2,3-tricarboxypropan-2-yloxy)ethyl]butanedioate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Magnesium;2-hydroxy-2-[2-oxo-2-(1,2,3-tricarboxypropan-2-yloxy)ethyl]butanedioate
• 英文别名: magnesium;2-hydroxy-2-[2-oxo-2-(1,2,3-tricarboxypropan-2-yloxy)ethyl]butanedioate
• 化学式: C12H12MgO13
• 分子量: 388.52
• InChiKey: KDSFGMYEFPXVJM-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -5.07
• 重原子数：
  26
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  239
• 氢给体数：
  4
• 氢受体数：
  13

文献信息

• Composition for treatment or reduction of symptoms related to premenstrual syndrome (pms), premenstrual disphoric disorder (pmdd), premenopause, menopause or female hormonal disorders in a pharmaceutical composition containing said form, and process for producing said pharmaceutical form and use of said composition
  申请人：EMS S.A.

  公开号：EP2808026A1

  公开（公告）日：2014-12-03

  The present invention relates to the field of food and medicines for the treatment or alleviation of premenstrual syndrome (PMS), premenstrual dysphoric disorder (PMDD), premenopause, menopause and female hormonal disorders. A first embodiment relates to a composition containing vitamins, minerals and oils. Additionally, the invention comprises a pharmaceutical form, more specifically in the form of soft capsules (also known as gelatin) containing the composition of the invention. In particular, the compositions of the invention contain vitamins and minerals in sources compatible with the association of vegetable oils, preferably borage oil, evening primrose oil, or a mixture of two oils, wherein the soft capsule contains a liquid and oily core.

  本发明涉及用于治疗或缓解经前期综合征（PMS）、经前期情感障碍（PMDD）、更年期前、更年期和女性荷尔蒙紊乱的食品和药品领域。第一个实施方案涉及一种含有维生素、矿物质和油的组合物。此外，本发明还包括一种药物形式，更具体地说是含有本发明组合物的软胶囊（也称为明胶）形式。特别是，本发明的组合物含有与植物油（最好是琉璃苣油、月见草油或两种油的混合物）结合的维生素和矿物质，其中软胶囊含有液体和油性核心。
• COMPOSITION FOR TREATMENT OR REDUCTION OF SYMPTOMS RELATED TO PREMENSTRUAL SYNDROME (PMS), PREMENSTRUAL DISPHORIC DISORDER (PMDD), PREMENOPAUSE, MENOPAUSE OR FEMALE HORMONAL DISORDERS, IN A PHARMACEUTICAL COMPOSITION CONTAINING SAID FORM, AND PROCESS FOR PRODUCING SAID PHARMACEUTICAL FORM AND USE OF SAID COMPOSITION
  申请人：EMS S.A.

  公开号：US20140356424A1

  公开（公告）日：2014-12-04

  The present invention relates to the field of food and medicines for the treatment or alleviation of premenstrual syndrome (PMS), premenstrual dysphoric disorder (PMDD), premenopause, menopause and female hormonal disorders. A first embodiment relates to a composition containing vitamins, minerals and oils. Additionally, the invention comprises a pharmaceutical form, more specifically in the form of soft capsules (also known as gelatin) containing the composition of the invention. In particular, the compositions of the invention contain vitamins and minerals in sources compatible with the association of vegetable oils, preferably borage oil, evening primrose oil, or a mixture of two oils, wherein the soft capsule contains a liquid and oily core.
• [EN] METHOD AND APPARATUS TO PRODUCE HYDROGEN-RICH MATERIALS<br/>[FR] PROCÉDÉ ET APPAREIL POUR PRODUIRE DES MATÉRIAUX RICHES EN HYDROGÈNE
  申请人：CENTAQUA INC

  公开号：WO2014133695A1

  公开（公告）日：2014-09-04

  Hydrogen molecule (H2) has been indicated as a novel anti-oxidant reagent specifically targeting OH free radicals. This invention discloses the methods and apparatus that can be used to increase the hydrogen concentration in water, in beverages, and in other hydrogen absorbing materials through a sealed hydrogen gas producing chamber made of materials that have good hydrogen permeability and can withhold gas pressure. The disclosed method and apparatus can increase the hydrogen concentration quickly without leaking other chemical by-products of the gas producing system into the treated materials.