(2R,3S,4R,5S)-N-(2-aminoethyl)-2,3,4,5-tetrahydroxy-N'-propylhexanediamide

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (2R,3S,4R,5S)-N-(2-aminoethyl)-2,3,4,5-tetrahydroxy-N'-propylhexanediamide
• 化学式: C₁₁H₂₃N₃O₆
• 分子量: 293.32
• InChiKey: UDOJQEPEQSLZSA-RYPBNFRJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.7
• 重原子数：
  20
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  165
• 氢给体数：
  7
• 氢受体数：
  7

文献信息

• NANOPARTICLES STABILIZED WITH NITROPHENYLBORONIC ACID COMPOSITIONS
  申请人：CALIFORNIA INSTITUTE OF TECHNOLOGY

  公开号：US20140249203A1

  公开（公告）日：2014-09-04

  Described herein are carrier nanoparticles comprising a polymer containing a polyol coupled to a polymer containing a boronic acid, configured to present the polymer containing a boronic acid to an environment external to the nanoparticle. Targeted versions of the described nanoparticles are also described, as are related compositions, methods and systems.

  本文描述了一种载体纳米颗粒，其中包含一个含有多元醇的聚合物和一个含有硼酸的聚合物，设计用于将含有硼酸的聚合物呈现给纳米颗粒外部的环境。还描述了所述纳米颗粒的定向版本，以及相关的组合物、方法和系统。
• EGFR-TARGETED NANOPARTICLES
  申请人：CALIFORNIA INSTITUTE OF TECHNOLOGY

  公开号：US20170000902A1

  公开（公告）日：2017-01-05

  Described herein are carrier nanoparticles comprising a polymer containing a polyol coupled via a boronic ester to a polymer containing a boronic acid, configured to present the polymer containing a boronic acid to an environment external to the nanoparticle. EGFR-targeted versions of the described nanoparticles are also described, as are related compositions, methods and systems.
• US9132097B2
  申请人：——

  公开号：US9132097B2

  公开（公告）日：2015-09-15
• US9446149B2
  申请人：——

  公开号：US9446149B2

  公开（公告）日：2016-09-20