2,3,3,3-tetrafluoro-2-[(6S)-4,4,5-trifluoro-6-(1,1,2,2,3,3,3-heptafluoropropoxy)-3,6-dimethyl-5-(trifluoromethyl)nonan-3-yl]oxypropanoic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2,3,3,3-tetrafluoro-2-[(6S)-4,4,5-trifluoro-6-(1,1,2,2,3,3,3-heptafluoropropoxy)-3,6-dimethyl-5-(trifluoromethyl)nonan-3-yl]oxypropanoic acid
• 化学式: C₁₈H₁₉F₁₇O₄
• 分子量: 622.3
• InChiKey: GBPBJFXFTZUZDV-GHNGPNRHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.1
• 重原子数：
  39
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  55.8
• 氢给体数：
  1
• 氢受体数：
  21

文献信息

• [EN] COMPOSITIONS, METHODS AND SYSTEMS FOR POLYMERASE CHAIN REACTION ASSAYS<br/>[FR] COMPOSITIONS, PROCÉDÉS ET SYSTÈMES POUR DES ESSAIS DE RÉACTION EN CHAÎNE PAR POLYMÉRASE
  申请人：BIO RAD LABORATORIES

  公开号：WO2014138711A1

  公开（公告）日：2014-09-12

  The present disclosure provides methods, devices, systems and compositions for detecting nucleic acids in polymerase chain reaction assays, such as droplet digital polymerase chain reaction (ddPCR) assays. The present disclosure provides methods, devices, systems and compositions for detecting nucleic acids in ddPCR assays using intercalating dyes. A dual surfactant system with at least one fluorosurfactant and at least one non-ionic non-fluorosurfactant may be employed for droplet generation and nucleic acid detection.