N-甲基哒嗪-4-胺 | 16401-70-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 中文名称: N-甲基哒嗪-4-胺
• 英文名称: N-methylpyridazin-4-amine
• CAS: 16401-70-0
• 化学式: C₅H₇N₃
• mdl: MFCD09999398
• 分子量: 109.131
• InChiKey: IYYGTADJURIVJO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.2
• 重原子数：
  8
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  37.8
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-氯噻唑-4-甲酸 、 N-甲基哒嗪-4-胺 在 benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate 、 三乙胺 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 16.0h， 以61%的产率得到2-chloro-thiazole-4-carboxylic acid methyl-pyridazin-4-yl-amide
  参考文献：
  名称：

  [EN] PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS
  [FR] COMPOSÉS PYRIDAZINE DESTINÉS À LA LUTTE CONTRE LES NUISIBLES INVERTÉBRÉS

  摘要：

  本发明涉及式(I)或(II)的吡啶嗪化合物及其盐和N-氧化物，其中A是取代或未取代的噁唑基、硫唑基或咪唑基；V为C(RV)或N；W为C(RW)或N；但要求V或W为N；Rt、Ru、Rv、Rw为H、卤素、C1-C4烷基等；X1为S、O或NR1a，其中R1a选择H、C1-C10烷基等；X2为OR2a、NR2bR2c、S(O)mR2d，其中m为0、1或2，R2a为C1-C4烷基、C1-C4卤代烷基等，R2b、R2c为H、C1-C4烷基、C1-C4卤代烷基等，或R2b和R2c与它们所连接的氮原子形成杂环，R2d为C1-C4烷基、C1-C4卤代烷基、C3-C6环烷基等；R1为H、CN、C1-C10烷基等。本发明还涉及一种控制无脊椎动物害虫的方法，一种保护植物繁殖材料和/或生长的植物的方法，包括至少一种本发明化合物的植物繁殖材料，一种用于治疗或保护动物免受寄生虫感染的方法，以及一种含有至少一种本发明化合物的农业组合物。

  公开号：

  WO2011003796A1

文献信息

• [EN] PESTICIDALLY ACTIVE SUBSTITUTED PYRIDYL CARBOXAMIDES<br/>[FR] PYRIDYL-CARBOXAMIDES SUBSTITUÉS ACTIFS EN TANT QUE PESTICIDES
  申请人：SYNGENTA PARTICIPATIONS AG

  公开号：WO2014166795A1

  公开（公告）日：2014-10-16

  Compounds of formula I wherein m is 0 or 1; Z is methine or nitrogen; X is oxygen or sulfur, R1 is C1-C6-alkyl, halo-C1-C6-alkyl, C3-C6-cycloalkyl or C2-C6-alkynyl; R2 is C1-C6-alkyl, C1-C6-haloalkyl, C3-C6-cycloalkyl, halo-C3-C6-cycloalkyl, fluoro, chloro or bromo; R3 is C1-C3-alkyl; R4 is hydrogen, C1-C6-alkyl, fluoro, chloro, bromo or cyano; n is 0, 1, 2 or 3; R5 is hydrogen, fluoro,chloro or bromo; and agrochemically acceptable salts and enantiomers of those compounds can be used as insecticides and can be prepared in a manner known per se.

  式I的化合物，其中m为0或1；Z为亚甲基或氮；X为氧或硫，R1为C1-C6烷基，卤代C1-C6烷基，C3-C6环烷基或C2-C6炔基；R2为C1-C6烷基，C1-C6卤代烷基，C3-C6环烷基，卤代C3-C6环烷基，氟，氯或溴；R3为C1-C3烷基；R4为氢，C1-C6烷基，氟，氯，溴或氰基；n为0、1、2或3；R5为氢，氟，氯或溴；这些化合物的农药可接受的盐和对映异构体可用作杀虫剂，并且可以按照已知的方法制备。
• Pyridazine Compounds for Controlling Invertebrate Pests
  申请人：Le Vezouet Ronan

  公开号：US20120110705A1

  公开（公告）日：2012-05-03

  The present invention relates to pyridazine compounds of formulae I or II and the salts and N-oxides thereof, wherein A is a substituted or unsubstituted isoxazole or isothiazole radical; V is C(R v ) or N; W is C(R w ) or N; with the proviso that either V or W is N; R t , R u , R v , R w are H, halogen, C 1 -C 4 -alkyl and the like; X 1 is S, O or NR 1a , wherein R 1a is selected H, C 1 -C 10 -alkyl and the like; X 2 is OR 2a , NR 2b R 2c , S(O) m R 2d , wherein m is 0, 1 or 2, R 2a is C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl and the like, R 2b , R 2c are H, C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl and the like, or R 2b and R 2c together with the nitrogen atom to which they are bound form a heterocycle, and R 2d is C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl, C 3 -C 6 -cycloalkyl and the like; and R 1 is H, CN, C 1 -C 10 -alkyl and the like. The present invention further relates to a method for controlling invertebrate pests, to a method for protecting plant propagation material and/or the plants which grow therefrom, to plant propagation material, comprising at least one compound according to the present invention, to a method for treating or protecting an animal from infestation or infection by parasites and to an agricultural composition containing at least one compound according to the present invention.

  本发明涉及式I或式II的吡啶嗪化合物及其盐和N-氧化物，其中A是取代或未取代的异噁唑或异硫唑基团；V为C（Rv）或N；W为C（Rw）或N；但要求V或W为N；Rt、Ru、Rv、Rw为H、卤素、C1-C4烷基等；X1为S、O或NR1a，其中R1a为H、C1-C10烷基等；X2为OR2a、NR2bR2c、S（O）mR2d，其中m为0、1或2，R2a为C1-C4烷基、C1-C4卤代烷基等，R2b、R2c为H、C1-C4烷基、C1-C4卤代烷基等，或者R2b和R2c与它们所连接的氮原子形成杂环，且R2d为C1-C4烷基、C1-C4卤代烷基、C3-C6环烷基等；R1为H、CN、C1-C10烷基等。本发明还涉及一种控制无脊椎动物害虫的方法，一种保护植物繁殖材料和/或由其生长的植物的方法，包括至少一种本发明化合物的植物繁殖材料，一种用于治疗或保护动物免受寄生虫感染或侵染的方法，以及包含至少一种本发明化合物的农业组合物。
• Novel Pesticidal Pyrazole Compounds
  申请人：Defieber Christian

  公开号：US20140045690A1

  公开（公告）日：2014-02-13

  The present invention relates to novel pyrazoles of formula I wherein the variables are as defined in the description, a method for controlling invertebrate pests, a method for protecting plant propagation material and/or the plants which grow therefrom, to plant propagation material, comprising at least one compound according to the present invention, and to an agricultural composition.

  本发明涉及式I的新型吡唑，其中变量如描述中所定义，用于控制无脊椎动物害虫的方法，用于保护植物繁殖材料和/或从中生长的植物的方法，包括至少一种根据本发明的化合物的植物繁殖材料，并涉及一种农业组合物。
• PYRAZOLE COMPOUND AND PESTICIDAL MIXTURES COMPRISING A PYRAZOLE COMPOUND
  申请人：BASF SE

  公开号：US20150150257A1

  公开（公告）日：2015-06-04

  The present invention relates to pesticidal mixtures comprising as active compounds 1) at least one pyrazole compound A selected from the compounds of formula I: wherein the variables have the meaning as defined in the description, and 2) at least one further compound B selected from the compounds of the following groups A.1, A.2, A.3, A.4, A.5, A.6, A.7, A.8, A.9, A.10, A.11, A.12, A.13, A.14, A.15, A.16, A.17, F.1, F.2, F.3, F.4, F.5, F.6, F.7, F.8, F.9, F.10 and F.11 as defined in the specification. The present invention also relates to novel pyrazole compounds of the formula I. The present invention also relates to methods and use of these mixtures and novel compounds for combating invertebrate pests such as insects, arachnids or nematodes in and on plants, and for protecting such plants being infested with pests, especially also for protecting plant propagation material as like seeds.

  本发明涉及一种杀虫混合物，包括以下活性化合物：1）至少一种从式I化合物中选择的吡唑类化合物A，其中变量的含义如说明书所定义，以及2）至少一种从以下A.1、A.2、A.3、A.4、A.5、A.6、A.7、A.8、A.9、A.10、A.11、A.12、A.13、A.14、A.15、A.16、A.17、F.1、F.2、F.3、F.4、F.5、F.6、F.7、F.8、F.9、F.10和F.11化合物组中选择的进一步化合物B，如说明书中定义的。本发明还涉及式I的新的吡唑类化合物。本发明还涉及使用这些混合物和新化合物的方法，用于在植物内外对抗无脊椎动物害虫，例如昆虫、蜘蛛或线虫，并保护被害虫侵害的植物，特别是用于保护植物繁殖材料，例如种子。
• Pyridazine compounds for controlling invertebrate pests
  申请人：Le Vezouet Ronan

  公开号：US08937177B2

  公开（公告）日：2015-01-20

  The present invention relates to pyridazine compounds of formulae I or II and the salts and N-oxides thereof, wherein the substituents are as defined in the description, a method for controlling invertebrate pests, to a method for protecting plant propagation material and/or the plants which grow therefrom, to plant propagation material, comprising at least one compound according to the present invention, to a method for treating or protecting an animal from infestation or infection by parasites and to an agricultural composition containing at least one compound according to the present invention.

  本发明涉及式I或式II的吡啶嗪化合物及其盐和N-氧化物，其中取代基如描述中所定义，一种控制无脊椎动物害虫的方法，一种保护植物繁殖材料和/或其生长的植物的方法，包括至少一种根据本发明的化合物的植物繁殖材料，一种用于治疗或保护动物免受寄生虫感染或感染的方法，以及包含至少一种根据本发明的化合物的农业组合物。