(2-phenylacetyl) (Z,12R)-12-hydroxyoctadec-9-enoate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (2-phenylacetyl) (Z,12R)-12-hydroxyoctadec-9-enoate
• 化学式: C₂₆H₄₀O₄
• 分子量: 416.6
• InChiKey: VMFJGRWNUCJOMU-GMLVJLLBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.4
• 重原子数：
  30
• 可旋转键数：
  19
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  63.6
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Modifying taste and sensory irritation of smokeless tobacco and non-tobacco products
  申请人：Altria Client Services LLC

  公开号：US10799548B2

  公开（公告）日：2020-10-13

  Tobacco products comprising smokeless tobacco products and active ingredients, including those that antagonize nicotinic acetylcholine receptors, the TRPV1 channel, and/or the TRPA1 channel are disclosed. Nicotine replacement therapies comprising active ingredients, including those that antagonize nicotinic acetylcholine receptors, the TRPV1 channel, and/or the TRPA1 channel. The active ingredient may reduce or eliminate sensory irritation arising due to use of the product. Analgesic compositions comprising active ingredients. Methods of reducing taste and sensory irritation by employing an active ingredient.

  本研究公开了由无烟烟草制品和活性成分（包括拮抗烟碱乙酰胆碱受体、TRPV1通道和/或TRPA1通道的活性成分）组成的烟草制品。 尼古丁替代疗法包含活性成分，包括拮抗烟碱乙酰胆碱受体、TRPV1 通道和/或 TRPA1 通道的活性成分。 活性成分可减少或消除因使用产品而产生的感官刺激。 包含活性成分的镇痛组合物。 通过使用活性成分减少味觉和感觉刺激的方法。
• MODIFYING TASTE AND SENSORY IRRITATION OF SMOKELESS TOBACCO AND NON-TOBACCO PRODUCTS
  申请人：Altria Client Services Inc.

  公开号：EP2967125A2

  公开（公告）日：2016-01-20
• US20140271946A1
  申请人：——

  公开号：US20140271946A1

  公开（公告）日：2014-09-18
• [EN] MODIFYING TASTE AND SENSORY IRRITATION OF SMOKELESS TOBACCO AND NON-TOBACCO PRODUCTS<br/>[FR] MODIFICATION DU GOÛT ET DE L'IRRITATION SENSORIELLE DE PRODUITS AVEC ET SANS TABAC SANS FUMÉE
  申请人：ALTRIA CLIENT SERVICES INC

  公开号：WO2014151434A2

  公开（公告）日：2014-09-25

  Tobacco products comprising smokeless tobacco products and active ingredients, including those that antagonize nicotinic acetylcholine receptors, the TRPV1 channel, and/or the TRPA1 channel are disclosed. Nicotine replacement therapies comprising active ingredients, including those that antagonize nicotinic acetylcholine receptors, the TRPV1 channel, and/or the TRPA1 channel. The active ingredient may reduce or eliminate sensory irritation arising due to use of the product. Analgesic compositions comprising active ingredients. Methods of reducing taste and sensory irritation by employing an active ingredient.